Unoprostone ophthalmic Disease Interactions
There is 1 disease interaction with unoprostone ophthalmic.
Unoprostone ophthalmic (applies to unoprostone ophthalmic) renal/liver disease
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Unoprostone isopropyl is hydrolyzed by esterases in the cornea and conjunctival epithelium to the active free acid form, which is absorbed systemically and metabolized by the liver. The metabolites are eliminated by the kidney. Unoprostone isopropyl has not been adequately studied in the treatment of patients with impaired renal and/or hepatic function. Therapy with unoprostone isopropyl ophthalmic solution should be administered cautiously in such patients.
Unoprostone ophthalmic drug interactions
There are 7 drug interactions with unoprostone ophthalmic.
More about unoprostone ophthalmic
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- During pregnancy
- Drug class: ophthalmic glaucoma agents
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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