Unoprostone ophthalmic Pregnancy and Breastfeeding Warnings

Unoprostone ophthalmic is also known as: Rescula

Unoprostone ophthalmic Pregnancy Warnings

Unoprostone ophthalmic has been assigned to pregnancy category C by the FDA. Animal studies have revealed increased evidence of miscarriages, a decreased number of live fetuses, and an increase in the number of stillborns following large subcutaneous doses. There are no controlled data in human pregnancy. Unoprostone undergoes minimal systemic absorption after ocular administration (<1.5 ng/mL). Unoprostone ophthalmic is only recommended for use during pregnancy when benefit outweighs risk.

Unoprostone ophthalmic Breastfeeding Warnings

There are no data on the excretion of topically administered unoprostone ophthalmic into human milk. It is excreted in rat milk after intravenous administration. Unoprostone undergoes minimal systemic absorption after ocular administration (<1.5 ng/mL). The manufacturer recommends caution when administering unoprostone ophthalmic to nursing women.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web5)