Skip to Content

epinephrine (Ophthalmic route)

Pronunciation

ep-i-NEF-rin

Commonly used brand name(s)

In Canada

  • Epinal

Available Dosage Forms:

  • Solution

Therapeutic Class: Antiglaucoma

Pharmacologic Class: Adrenergic

Chemical Class: Alkylarylamine

Uses For epinephrine

Epinephrine solution is used for mydriasis (dilation or widening the pupil of the eye) during eye surgery.

Slideshow: Measles 101: What You Need To Know

epinephrine is to be given only by or under the direct supervision of your doctor.

Before Using epinephrine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For epinephrine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to epinephrine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of epinephrine solution in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of epinephrine solution in the elderly.

Pregnancy

Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving epinephrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using epinephrine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Dihydroergotamine
  • Isocarboxazid
  • Linezolid
  • Phenelzine
  • Tranylcypromine

Using epinephrine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amitriptyline
  • Amoxapine
  • Bucindolol
  • Carteolol
  • Carvedilol
  • Clomipramine
  • Desipramine
  • Digoxin
  • Dilevalol
  • Dothiepin
  • Doxepin
  • Entacapone
  • Halothane
  • Imipramine
  • Iobenguane I 123
  • Levalbuterol
  • Levobunolol
  • Lofepramine
  • Metipranolol
  • Nadolol
  • Nortriptyline
  • Opipramol
  • Oxprenolol
  • Penbutolol
  • Pindolol
  • Propranolol
  • Protriptyline
  • Rasagiline
  • Sotalol
  • Tertatolol
  • Timolol
  • Trimipramine

Using epinephrine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Labetalol

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of epinephrine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Allergy to sulfites or
  • Asthma—epinephrine contains sodium bisulfite, which can make these conditions worse.
  • Angina (severe chest pain) or
  • Arrhythmia or
  • Diabetes or
  • Heart or blood vessel disease or
  • Hypertension (high blood pressure) or
  • Hyperthyroidism (overactive thyroid) or
  • Parkinson's disease or
  • Pheochromocytoma (adrenal disease) or
  • Stroke, history of—Use with caution. May make these conditions worse.

Proper Use of epinephrine

A doctor or other trained health professional will give you epinephrine. epinephrine is used as an irrigating solution during eye surgery.

Precautions While Using epinephrine

Your doctor will check your progress closely while you are receiving epinephrine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.

epinephrine Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known
  • Blurred vision or other changes in vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

The information contained in the Truven Health Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.

Copyright 2015 Truven Health Analytics, Inc. All Rights Reserved.

Hide
(web1)