Disease Interactions

Esomeprazole Disease Interactions

There is 1 disease interaction with esomeprazole:

Esomeprazole (Includes Esomeprazole) ⇔ Liver Disease

Moderate Potential Hazard, High plausibility

Applies to: Liver Disease

Esomeprazole is primarily metabolized by the liver. In patients with mild to moderate hepatic impairment (Child Pugh Class A and B), little drug accumulation has been observed following once-daily, multiple-dose administration. No dosage adjustments are necessary in these patients. In severe hepatic impairment (Child Pugh Class C), however, substantial increases in plasma drug concentrations have been demonstrated. The manufacturer recommends a maximum dosage of 20 mg once daily in patients with severe liver disease.


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esomeprazole drug Interactions

There are 139 drug interactions with esomeprazole

esomeprazole food/lifestyle Interactions

There is 1 food/lifestyle interaction with esomeprazole

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