Zanaflex Alternatives Compared
Zanaflex | Cyclobenzaprine | Tizanidine |
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Zanaflex (tizanidine) | Cyclobenzaprine | Tizanidine |
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Prescription only
Prescribed for Cluster Headaches, Muscle Spasm. Zanaflex may also be used for purposes not listed in this medication guide. |
Prescription only
Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... View more |
Prescription only
Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. The dosage should be individualized and because it only lasts for a short time in the body, can be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
Popular comparisons
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More about Zanaflex (tizanidine) | More about Cyclobenzaprine | More about Tizanidine | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 13% reported a negative effect. |
Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. |
Tizanidine has an average rating of 6.1 out of 10 from a total of 377 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 30% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Zanaflex side effects in more detail. |
See also: cyclobenzaprine side effects in more detail. |
See also: tizanidine side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Zanaflex prices |
View all cyclobenzaprine prices |
View all tizanidine prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
Amrix, Comfort Pac with Cyclobenzaprine | Zanaflex | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
2.5 hours |
72 hours |
2.5 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 608 drugs are known to interact with Zanaflex:
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A total of 440 drugs are known to interact with cyclobenzaprine:
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A total of 608 drugs are known to interact with tizanidine:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
November 27, 1996 |
August 26, 1977 |
November 27, 1996 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.