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Zoledronic acid for Osteoporosis User Reviews (Page 5)

Brand names: Reclast, Zometa, Aclasta

Zoledronic acid has an average rating of 4.9 out of 10 from a total of 239 reviews for the treatment of Osteoporosis. 34% of reviewers reported a positive experience, while 45% reported a negative experience.

Reviews for Zoledronic acid

  • Joe
  • Taken for 1 to 6 months
  • February 29, 2020

Reclast (zoledronic acid) "I can't speak to its effectiveness as I had it infused only about 4 weeks ago, but the side effects mostly went away in about 1 week. What is left, is skin irritations, general tightness of my body and extra sweating. All seem to be going away soon. If it works, I will take it again."

8 / 10
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  • Kim...
  • Taken for less than 1 month
  • May 21, 2023

Reclast (zoledronic acid) "On 12/6/22, I received my first (and only) Zoledronic Acid Injection (Reclast) to prevent osteoporosis from coming back (currently osteopenia) after taking Prolia shots for 2 1/2 years. I don't know whether or not Reclast injection worked to prevent osteoporosis yet, because I'm not scheduled for a bone density test until June. What I do know is that I have been in chronic pain every day since that day! There was literally ZERO warning from my rheumatologist about potential side effects or things that it could possibly trigger. And, I foolishly did not research it myself. Within 6 days of the injection, I was limping and in intense pain. They had me come in the next day. Long, story short, it is their belief that the Reclast triggered Psoriatic Arthritis that was already in my body (never had it before, but I did have mild psoriasis. I've have 2 BAD flares since the original flare, been in PT, on multiple medicines. In pain every day of my life. NEVER AGAIN will I have Reclast!"

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 31, 2023

Reclast (zoledronic acid) "I had the Reclast infusion. Not one side effect. Day before and day of and some the day after the infusion, I took Tylenol extra strength every 8 hours and drank lots of water. I believe this is the key to no side effects."

10 / 10
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9 Report

Frequently asked questions

  • Avara
  • Taken for 2 to 5 years
  • November 13, 2016

Aclasta (zoledronic acid) "I have Osteogenesis Imperfecta. After getting Aredia for years and not seeing much improvement (maybe it prevented deterioration), I received Aclasta for 2 years and my bone density went from very fragile to just below average. That was 2 years ago. No side effects and no deterioration as of yet. I'm very happy to be repaired."

10 / 10
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  • Renee
  • Taken for 6 months to 1 year
  • June 25, 2023

Reclast (zoledronic acid) "I recently turned 67 and had my second annual dose of Reclast five days ago. After the first infusion in 2022, I developed body aches and night chills for perhaps up to one week. My second infusion experience has been quite worse, although I read that it's uncommon to feel side effects after the second infusion. My symptoms began the evening of day 2, with mild head and neck achiness. By nighttime, I had severe flu-like chills and more severe aching radiating to my arms and shoulders. Day 3, aching in legs, calves, big toes, areas where I have mild arthritis in my joints, milder night chills. Day 4, yesterday, extreme aching, now upper-mid back on both sides, radiating through my breastbone, actual spasms. Excruciating to roll over at night in bed. Today is day 5, and upper back pain and spasms are only on the left side but quite painful. Still spasming. I've been taking Extra Strength Tylenol, but it is not really helping. I decided to discontinue Reclast in the future."

4 / 10
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Are you taking this medicine?

  • lanadee
  • Taken for less than 1 month
  • October 19, 2019

Reclast (zoledronic acid) "I had the Reclast infusion on Thursday and first my vein collapsed and fluid built under my skin. Perhaps a poor choice of veins. I am 68. My arm hurt the rest of that day of course. Then the next two days I have had the "flu" like symptoms. (Fever, muscle aches and pains, weakness). I am HOPING this subsides soon. I have things to do, places to go, people to see. Ha The jury is out as to whether or not I would take it again."

5 / 10
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  • Wedding...
  • Taken for less than 1 month
  • April 23, 2017

Reclast (zoledronic acid) "Had my first Reclast IV on Thursday morning. After a couple of hours started hurting all over and feeling terrible. By evening started running a fever of 100 - 101, had chills, nausea, pain all over and couldn't get out of bed until Saturday evening. Took Tylenol every 4 hours. On Sunday still did not feel a lot better but fever was getting better. Hope this gets better really soon."

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  • Yami...
  • Taken for 5 to 10 years
  • May 21, 2018

Reclast (zoledronic acid) "I have been reading the other comments about side effects that happen months later. I have been taking Reclast once a year since 2009, after my cancer treatments were over. I have never had any side effects or bad experiences with it. It's cool as heck to me. I will definitely continue to use it for as long as my oncologist seems it necessary."

9 / 10
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  • Disgu...
  • Taken for 6 months to 1 year
  • February 3, 2021

Reclast (zoledronic acid) "I WOULD NEVER TAKE THIS HORRIBLE DRUG RECLAST AGAIN! I experience severe itching which I was prescribed Cetirizine and Pepcid. But the worst part of this was I had just spent hundreds on my teeth with a new bridge/crown. A few months after the RECLAST my bridge came loose, when they removed it the teeth were broken off, flush with the gum, nothing to adhere it back to. Only a few months later the crown next to it started wiggling and it came and was also broken off at the gum. Counting the teeth that was replaced with the bridge, I have five teeth missing (the front tooth til the last tooth in the back. It could continue on with my front teeth, I'm praying it doesn't but time will tell. I would NEVER, EVER, take this HORRIBLE, DANGEROUS, drug EVER AGAIN. I am looking into a class action law suit ?? I found a lawyer that accepts this type claim but they have so many they can't accept anymore right now."

1 / 10
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  • Tilla
  • Taken for 1 to 6 months
  • April 8, 2020

Aclasta (zoledronic acid) "I had no side effects. Before the dose of Aclasta I had a typical tennis elbow. It is still painful at times. What I only experience now is hair loss since getting tis in Feb. I'm aware that you do shed a couple of hairs before a season change. But this is different. After a hair shampooing the hair came loose as if I'm having cancer treatment. Where I walk. All over in the house you will find hair on the floor. Did anyone else experience this same effect?"

5 / 10
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  • Bev
  • October 13, 2019

Reclast (zoledronic acid) "I had an Reclast infusion last Thursday and felt fine the rest of the day. I was tired and went to bed waking up with severe nausea and bone pain which created anxiety on top of that. The pain was intense and I felt like a truck had been dropped on me. This is day 3 after the infusion and the pain has receded some. The doctor said take ibuprofen on Tylenol. That didn't do it for me. I took Tramadol to get some pain relief. My doctor said I only had to have it once every 3 years and that will be soon enough to decide if I want to do it again. Today I'm a little unhappy over how sick I was and reading other comments, I hope I don't residual effects."

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  • Nick
  • Taken for less than 1 month
  • May 4, 2019

Reclast (zoledronic acid) "Horrible experience. First infusion and after this terrible pain I'm not sure I would do this again. Extreme joint and muscle pain. This is my third day after treatment and the pain just moves from one place to another. I doubt that I would do this again. I want my life back."

5 / 10
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  • Stell...
  • Taken for less than 1 month
  • February 4, 2019

Reclast (zoledronic acid) "I received a Reclast infusion 1/10/2019. Within 6 hours post infusion started to have elbow pain and within 12 hours post infusion pretty deep bone pain in sternum along with flu symptoms. Fevers spiked to 102 at times for over 48 hours. All joints were painful. Day 3 and 4 post infusion severe pain in ankles and feet - unable to get out of bed independently but once I was moving around, things got easier. While the side effects may sound bad (and they were at times) if this increases bone density then I have no problem sacrificing a week or two of side effects."

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  • NGano
  • Taken for less than 1 month
  • October 13, 2019

Reclast (zoledronic acid) "Reclast IV last week, and I had side effects of sore throat, chills, headache, fever, severe bone, joint and muscle pain, in bed for the past 8 days. I originally was going to cancel the IV after reading all the side effects but the nurse talked me into it. Never again! I can’t really rate the drug as it’s only been a week."

3 / 10
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  • Maest...
  • Taken for 5 to 10 years
  • November 29, 2020

Zometa (zoledronic acid) "The Zometa was almost then end of me. I was 70yrs old when doctors in Sardinia gave me the Zometa for only a broken rib. They gave it me for 1 year. Meanwhile my bones were becoming weaker and weaker every day. My jaw become painful and was almost impossible to talk, to eat and chew. My bones started to have fractures without any particular accident. Doctors gave me Zometa for 6 years. After 1year, the Zometa caused me bone cancer. If Zometa is good for bones, then why after 1year of infusions I've had bone cancer ?"

1 / 10
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  • Tracey
  • May 14, 2020

Aclasta (zoledronic acid) "Had 1st Aclasta Feb 2019 for Osteoporosis and I also have OI type 1. Had a fall and smashed knee cap in June then had 2nd Aclasta infusion in Feb this year with bone density test which went from Osteoporosis back to osteopenia. So its working. I was also given pamphlets to read about pros and cons b4 hand. So knew side effects."

10 / 10
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  • Candi...
  • September 17, 2016

Reclast (zoledronic acid) "I am 41 with Crohn's disease causing my lack of vitamin absorb. I had my monthly entyvio infusion and right after my first reclast infusion just yesterday. I was just fine until about 5 hours after when I started having diarrhea. It later turned into severe watery diarrhea shooting out into my Ostomy, chills, sweating, fever, aches, and weakness. I was told it may happen but was hoping not to me. If this helps me a few days of this is worth it and I will do it again. Like on Harry Potter "growing bones is a nasty business!" Lol"

3 / 10
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  • NiC
  • June 1, 2023

Reclast (zoledronic acid) "The WORST side effects - one week later still suffering from bone pain. The first night after IV - all side effects hit at once - fever, chills, nausea, dizziness, and the worst bone pain - it was even painful to take a deep breath or to yawn. I do not know how this passed FDA approval for humans. Totally unprepared for the horrendous side effects with no guarantee that it will be helpful for bone density. It was the worst experience and I would totally advise against taking this medication. If there was an option to give less than “1” I would do so."

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  • Pat...
  • Taken for 2 to 5 years
  • January 21, 2024

Reclast (zoledronic acid) "I had my 2nd Reclast infusion a week ago. Drank plenty of water before and after. Took precautionary acetaminophen for two days after. No side effects whatsoever. There was an improvement in bone density after 1st time (3 years ago)."

10 / 10
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  • Emhi
  • April 29, 2015

Aclasta (zoledronic acid) "I had my first Aclasta infusion in October 2014 on the recommendation of my Oncologist. I had been on Arimidex for breast cancer for 10 months. As yet I have no idea how effective it has been for my bone density. I took two days off work in preparation for any side effects - but am happy to report that i had ZERO side effects, nothing, not even a sniffle!! :)"

8 / 10
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  • Belm
  • Taken for 2 to 5 years
  • December 18, 2017

Reclast (zoledronic acid) "I’ve had the Reclast infusion two times now. I’m 68 and my osteoporosis is not severe, and only in a couple of areas. I haven’t experienced any side effects at all. No improved energy either, as some report. But, my doctor says my bone density has improved following another test. So, I’ll likely continue with what he recommends."

10 / 10
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  • JPano
  • Taken for 1 to 2 years
  • August 13, 2019

Reclast (zoledronic acid) "My first infusion of Reclast was September 2018. I had very minor side effects that lasted a few days. On 8/12/2019, I had my second Dexa Scan and my bone density in my spine has increased from 0% to 4%. I fractured my left femur January 2018, so the left leg was scanned the first time yesterday and no surprise I have Osteoporosis in my left leg, as well as my right femur. I'm still a high risk for a fracture. I've been going to the gym and taking many supplements to increase bone density. Not as much gain as I was hoping to see. I may try something else. I'm online searching today. I wish everyone good luck!. I'm 62 1/2. God bless."

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  • McGan
  • Taken for 1 to 6 months
  • January 28, 2023

Aclasta (zoledronic acid) "I had a 15 minute infusion 5 days ago. For about 16 hours I felt fine. The following afternoon I began to feel a headache, tiredness and generally felt ill. Tried sleeping it off. The next afternoon my chest felt sore, I had severe pain, like indigestion for most of the night. Day three, my joints have swollen and I have arthritic symptoms, my wrists are extremely painful, it hurts to even press the toilet button. I still have headaches. I regret having Aclasta. I am not prepared to recommend it at this stage."

1 / 10
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  • Jane
  • Taken for less than 1 month
  • June 20, 2023

Reclast (zoledronic acid) "I had my first Reclast infusion two weeks ago and I am suffering from back pain, chest pain, and a lot of gas. I am hoping it will go away in time. I almost went to the hospital as I thought I was having a heart attack. I would use this medication again if the side effects are temporary and it helps my osteoporosis. I'm praying these side effects are not long-term. I do not know yet if this is helping or not, should know in about a year."

5 / 10
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  • Chapm...
  • Taken for 1 to 2 years
  • January 9, 2020

Reclast (zoledronic acid) "My first Reclast was last January after I had a round of radiation treatment from dcis breast cancer. Oh, I am cured, Dears. I had only minor reactions.. a little fluish for about 12 hours and then freedom! I feel great and I am truly looking forward to this cancer checkup and another infusion. GlesFallsHospital the best ofr cancer recovery!"

10 / 10
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31 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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