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Medications for Hypercalcemia of Malignancy

Hypercalcemia of Malignancy is an excessive amount of calcium in the blood associated with malignant tumors.

Drugs used to treat Hypercalcemia of Malignancy

The following list of medications are in some way related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Zometa 4.5 5 reviews for Zometa to treat Hypercalcemia of Malignancy
Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sensipar Rate Add review
Rx C N
Generic name:
cinacalcet systemic
Drug class:
calcimimetics
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
dexamethasone Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Brand names:
Dexamethasone Intensol, De-Sone LA, Dxevo, HiDex
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
cinacalcet Rate Add review
Rx C N
Generic name:
cinacalcet systemic
Brand name:
Sensipar
Drug class:
calcimimetics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
zoledronic acid 5.4 6 reviews for zoledronic acid to treat Hypercalcemia of Malignancy
Rx D N
Generic name:
zoledronic acid systemic
Brand names:
Zometa, Reclast, Aclasta
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Xgeva 1.0 1 review for Xgeva to treat Hypercalcemia of Malignancy
Rx X N
Generic name:
denosumab systemic
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
prednisone Rate Add review
Rx C N
Generic name:
prednisone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
pamidronate Rate Add review
Rx D N
Generic name:
pamidronate systemic
Brand name:
Aredia
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
denosumab 2.7 3 reviews for denosumab to treat Hypercalcemia of Malignancy
Rx X N
Generic name:
denosumab systemic
Brand names:
Xgeva, Wyost
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Reclast Rate Add review
Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Aredia Rate Add review
Rx D N
Generic name:
pamidronate systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
Aclasta Rate Add review
Rx D N
Generic name:
zoledronic acid systemic
Drug class:
bisphosphonates
For consumers:
dosage, interactions, side effects
Dexamethasone Intensol Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
De-Sone LA Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
Dxevo Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
HiDex Rate Add review
Rx C N
Generic name:
dexamethasone systemic
Drug class:
glucocorticoids
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Wyost Rate Add review
Rx X N
Generic name:
denosumab systemic
Drug class:
miscellaneous bone resorption inhibitors
For consumers:
dosage, interactions,

Frequently asked questions

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Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.