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Zoloft User Reviews & Ratings (Page 5)

Zoloft has an average rating of 7.2 out of 10 from a total of 1,824 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Zoloft

  • Severe...
  • Taken for 1 to 6 months
  • May 6, 2014

For Obsessive Compulsive Disorder "I have suffered with severe health anxiety and obsessive compulsive disorder related to this anxiety for about 6 years. I would spend countless hours a day googling symptoms and doing certain health related rituals, and it was taking over my life. I finally talked to my doctor at the urging of my family and ended up on 50 mg of Zoloft. I didn't want to take it because part of my health anxiety is a fear of any type of medication. After about 3 weeks of it sitting untouched in my cabinet I started to take it. I didn't feel strange - no side effects. Maybe a little more sleepy at night? After about 3 weeks on Zoloft I noticed that I didn't have the urge to Google health symptoms anymore and I would *forget* to do some of my daily rituals."

9 / 10
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  • Mirac...
  • September 9, 2018

For Panic Disorder "I promised myself that I would write a review and try to help someone else if the medicine worked and boy did it!! This is truly a miracle pill. It helped me with everything including my panic attacks, anxiety, intrusive thoughts, and OCD rituals. I’m free again able to live a calm life. I will say the first few weeks were brutal. I had every side effect, nauseous, diarrhea , headaches, dizziness, some minor hair loss and more. I prayed this pill would help me and it did. Before it I had no quality of life and, to me, the side effects were worth it. I stuck it out for 3 months and I’m back to my old self and even better. I had very dark days. The fear was paralyzing and I couldn’t function. I couldn’t get through the day without my Xanax 0.25 frequently and now Xanax free! I started with 50mg for a month and then 100mg for 8 weeks. Today, I’m working, exercising, being the mom I want to be and take stress better. My panic suffering is over. Thank you Lord and Thank you ZOLOFT!"

9 / 10
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168 Report
  • Peach...
  • June 24, 2015

For Depression "I developed depression a few months ago and felt that I had truly lost my mind. I was beyond sad, crying constantly, terrifying intrusive thoughts, lost all interest in hobbies, friends, I thought that was it for me. I didn't feel that I would ever be my normal self ever again. Zoloft has completely eliminated my depression. The first week was almost unbearable but I cannot stress how much better I began to feel after about 2weeks. It is a miracle drug, I truly cannot express how well it has worked for me."

10 / 10
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234 Report

Frequently asked questions

  • JimMb...
  • August 18, 2013

For Obsessive Compulsive Disorder "I went years without getting help until about 8 months ago when I finally broke down, saw a doctor, and was prescribed Zoloft. This pill has given me my life back. I was diagnosed with Obsessive Compulsive Disorder, specifically intrusive/disturbing thoughts and obsessions. This disorder occupied all of my time and energy, to the point where life was unbearable and hopeless. About two weeks after starting Zoloft there were noticeable improvements. After 6 weeks, I was a different person. Anxiety-0, OCD, still there but more of a minor in convenience than life consuming. Side effects were typical at first: nausea, diarrhea, lightheaded, and insomnia. All of which subsided after a few weeks. I highly recommend that if you diagnosed, ask for Zoloft."

10 / 10
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  • Jgano
  • Taken for 6 months to 1 year
  • October 4, 2019

For Depression "Zoloft was life changing for me , for a long time I had doubt about starting anti- depressant. I took a chance and started with lexapro , it was okay but I was always so tired and I felt like something was missing. So I went to my doctor and switch to zoloft and I feel like this drug helped me in so many ways ! I'm no longer worried about everything, I no longer don't want to go to work or school, I'm more social and happy. Zoloft gave me back my normal life and I'm so grateful for it. If you feel generalized anxiety or panic disorder all the time, it is not normal and if you want to take a chance and start medication you will see that its not as bad as everyone thinks !"

10 / 10
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Are you taking this medicine?

  • Anony...
  • January 16, 2019

For Post Traumatic Stress Disorder "I spent a lot of time reading this forum while I was waiting for my medication to work, and I promised myself that I would share my experience once it worked. So here's my story: I was a victim of sextortion 4 years ago. After denying/questioning it for at least a year, I have finally admitted to myself that I have Post Traumatic Stress from this. I would experience intrusive thoughts/memories of the event, every day, all day. I felt depressed for the majority of the day, my anxiety got worse, I didn't think I'd ever get better. I was prescribed Zoloft back in December. I started out with 25mg, and worked my way up to 100mg, which happens to be the effective dose for me. Since being on the medication, I haven't been experiencing the intrusive thoughts/memories nearly as much, and when I do have memories, I don't feel so much shame. My moods have drastically improved overall. I can finally say "I'm fine" and mean it! About a month ago, I never would've thought it to be possible."

10 / 10
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  • Krista...
  • Taken for 1 to 6 months
  • May 12, 2017

For Panic Disorder "Let me start out by saying THIS IS THE FIRST REVIEW I HAVE EVER WRITTEN. I felt compelled to share my story and experience with Zoloft in hopes that it helps someone else. I agonized over the decision of whether or not to go on medication for an anxiety and panic disorder that was ruining my life. I was so fearful of side effects, weight gain, increased anxiety and all the other "what ifs". Finally, I submitted and figured I had nothing to lose. Let me just say 4 months on 50mg of Zoloft and I am loving life. Give this medication a chance, no one was more skeptical of me, to the point that I suffered more than 2 years before finally trying it. This medication CHANGED MY LIFE and I am so happy I decided to try it."

10 / 10
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190 Report

More FAQ

  • Alliey
  • Taken for less than 1 month
  • February 15, 2015

For Depression "I was on Celexa for a year and it wasn't working for me. Then my doctor prescribed me Zoloft and it's my fourth day taking it and I love it. I finally have a clear head on my shoulders. And for the first time in a long time, I don't feel depressed at all. I would highly recommend this to anyone who suffers from depression."

10 / 10
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227 Report
  • Blue...
  • Taken for 1 to 6 months
  • April 18, 2014

For Depression "On 50mg for 4 weeks then increased to 100mg for depression, panic attacks and obsessional thinking. I had few side effects, a slight hand tremor, yawning and difficulty sleeping. The only thing that lingered was the insomnia, but now that has settled down and I sleep okay. I feel so much better, panic attacks gone, obsessive compulsive disorder gone and my mood is lifting daily. I am enjoying life again and this medicine has been so right for me."

8 / 10
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242 Report
  • Wande...
  • March 20, 2014

For Depression "Zoloft. You made me REALIZE, I've been locked out of HEAVEN for too long (I've been dancing and cleaning on this Bruno Mars song all morning). That's how I feel on my medication! I'm on day 4 of 50 mg and I'm supposed to increase it to 100mg after 10 days. I have been having side effects since the first day such as shaking, abdominal pain, insomnia but nothing too major compared too what the "Beast" (yes! I call my anxiety the beast hehe) had me endure before. So I really don't mind those side effects because I know what's ahead of me is going to be spectacular. I've never had so much faith in my life before, at least not that I remember."

9 / 10
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  • MBM
  • June 2, 2020

For Social Anxiety Disorder "Hey there. I started with Zoloft for GAD and derealization. I started with 25mg for one week and then I upped on 50mg, but the side effects were too bad so I went down on 25mg. My God was the beginning terrible! Anxiety was soo much worse, feeling terrified, depressed, feeling guilt, crying, brain fog and nausea. I lost almost 8kg in 2 weeks because I couldn't eat. My Psychiatrist told me to take 0.5mg of Clonazepam till the side effects lift. After exactly 4 weeks I can say that all the side effects are gone. I feel a bit sleepy, but I am much more calm, no anxiety at all, no guilty feeling. Derealization is still here but much less, I don't care about her so she will go away with time too. I went back on work and started socalizing again. I take only 1/8 of Clonazepam. I will up my dose in a few days, but slowly. I PROMISE you that the starting side effects will pass. Trust me! I know how hard it is. This is a reminder for me too if the upping bring back the side effects."

9 / 10
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  • Framous
  • October 25, 2013

For Depression "I just wanted to say that if you find a medication that works well for you, stay on it! The mistake that I have made and others make far too often is to quit the meds once you feel better. If you feel bad before you find the right med that makes you feel better, then you should keep in mind that it is the med that's working. If it's working, stay on it. If you have been diagnosed. With ADHD or Bipolar, or a combination like many have, it's probably not going away...it's there to stay. I will agree that it sucks being labeled with any mental condition, and I know it's no fun taking meds, especially meds for the head....but if they work, and you need them...stay on them! Life is short, so enjoy it as much as possible!"

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  • DQano
  • Taken for 1 to 6 months
  • May 31, 2019

For Social Anxiety Disorder "I started taking this drug 50mg for social anxiety and depression and this has truly been amazing. At first reading some of the negative reviews and not focusing on the positive one I was nervous about trying it, but enough was enough. For the first few weeks yeah there were some side effects but they were not as severe as I thought. They went away after about a month. What this drug will do is meet you half way and provides a better outlook on things. Do I still have anxiety at times, of course, but its no where near what it used to be. This drug will meet you half way. Its nice going out in public and interacting with people, I didn't realize how normal it was. The meds work, but you have to want to change for you to really notice it. Hope this helps ya'll."

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140 Report
  • Nurse...
  • Taken for 6 months to 1 year
  • November 16, 2014

For Depression "I am 39 years old, was a new nurse and struggling with major depression. I had not been to a Dr in years and broke down crying at the first visit. Started 50 mg a day. Felt a little funny first couple days but now feel much better! Everyone noticed a change for the better and even got a promotion at work! Feel so much better and have not had any side effects!"

9 / 10
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226 Report
  • Rosie
  • Taken for 10 years or more
  • September 10, 2019

For Depression "I have been on Zoloft and the generic sertraline on and off for many many years, on 50 mg. Recently I developed symptoms of depression, panic etc due to health issues. I have a great GP who encourages me to manage my depression so with his agreement I increased my dose to 100 mg, and suffered every symptom for weeks. Anxiety, nausea, shaking, insomnia. After 10 weeks these symptoms have all but disappeared. After reading all the reviews I vowed to share my experience too. Remember the symptoms WILL go away. It may take longer for some people than others to feel better. You may feel good one day but not the next. Hang in there. It takes time. I now feel almost ready to go back to 50 mg."

8 / 10
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133 Report
  • Zovy
  • Taken for 1 to 2 years
  • November 29, 2016

For Obsessive Compulsive Disorder "It took a while, but Zoloft has been a total lifesaver for me. I had severe OCD/anxiety and later on depression as well. Anyone who's ever had crippling anxiety knows what mental torture it is. I was so afraid to try Zoloft but finally gave in when I felt like I had nothing to lose. I was on 50mg and the first few days I only felt a little dizzy but nothing else. On day 11, I first noticed some kind of shift. I remember looking at a tree and for the first time in years feeling joy, like I felt as a kid, and just enjoying its beauty vs fearing getting killed by a falling branch. About 6 weeks in I felt less tense overall but still felt it could be better. Started 100mg and my anxiety is gone. I feel normal again! Please give this a try!"

10 / 10
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187 Report
  • George
  • August 23, 2013

For Social Anxiety Disorder "Have struggled all my life with anxiety, worked out 7 days a week to try and control it. Panic attacks- just horrible- no lifts, no planes, no tunnels. Tried CBT, finally I thought I don't want to live this way anymore. Pill phobic, but finally I tried it, a quarter of a tablet for two weeks, then half again, for two weeks. What can I say? It had changed my life completely. I love it. I feel normal! No side effects. It took three months but felt better within weeks. All of you out there undecided, unsure, afraid of what you've read- please do yourself a favour and try it- be positive about it, open and give it a go- you won't regret it. I can fly, drive, amazing."

10 / 10
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246 Report
  • NewUser
  • January 29, 2009

For Depression "I just started Zoloft 3 days ago and the side effects so far have been very clear. For me, I haven't been able to eat. I've never been a good eater but I don't need to lose weight and I am eating maybe half what I used to just a few days ago. Nothing seems to taste very good, and I feel full after very little food. I get nausea for about 10-15 minutes about 4-5 times a day, that I didn't have before. My head feels really weird like I can feel the chemicals running though my brain. It's really weird. I had problems sleeping before taking Zoloft so not sure if that is a side effect. A lot of good reviews - going to stick it out."

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320 Report
  • Gerge
  • Taken for 1 to 6 months
  • August 23, 2013

For Panic Disorder "Ignore all negative comments, it stopped me from taking this medicine for two years. I was unable to work, drive, fly, function. Panic attacks, exhausted all my life. Sporty, lived for exercise, tried CBT. Am pill phobic. My life was a mess so I worked with a great doc starting very slowly and here I am 6 months later and I'm a new person. No panic, mild anxiety every now and then like normal people but I'm manageable. Please do it. It's a wonderful medicine, no side effects and it'll change your life. Start living."

10 / 10
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244 Report
  • Marta
  • October 30, 2013

For Obsessive Compulsive Disorder "Zoloft has changed my life. I used to feel like I wanted to stop living. I had anxiety with racing thoughts, feeling short of breath, social anxiety, and obsessive bad thoughts. I no longer feel suicidal and my irritability has gotten 100% better. I still get short of breath sometimes and worry about things but overall just feel so much more even keeled. I waited a month before taking it after getting the prescription because I didn't want to take meds and felt like it was a cop out. I'm so happy I decided to give it a try. I haven't gained weight and don't feel like my emotions are dulled. I feel happier and more hopeful. Strongly recommend."

9 / 10
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240 Report
  • bride...
  • Taken for less than 1 month
  • November 22, 2019

For Panic Disorder "I was so nervous about starting this Zoloft. I read these reviews over and over for days. I was experiencing extremely bad panic attacks and suffered from depression. I finally bit the bullet and took it. The first day (took it in the morning as directed) I felt really weird, super drowsy and lethargic. Switched it to taking it at night and it was much better. I was still drowsy during the day for about a week though even after taking it at night. I didn't have much of an appetite at first either and lost some weight which I'm not complaining about. lol. Now after almost a month of taking it I am soooo glad I did. I feel like myself again. It might be weird at first but please if you need it then try it, and if it sucks tell your doctor but if you can handle the side effects stick with it, it really does get better and totally worth it! I'm having almost zero negative side effects now and am out and about doing the things I had a seriously hard time doing before."

9 / 10
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  • Anony...
  • Taken for 1 to 6 months
  • October 28, 2022

For Obsessive Compulsive Disorder "For those suffering from OCD, bad thoughts, overthinking, depression, terrible headaches, give ZOLOFT a chance. First month don't expect much. I am on 100 mg. This medicine helped me so much. Get rid of your rituals and ruminating. Find peace with the help of zoloft. You can't make it alone. It is so hard. I had no hard side effects. Just some night urination and less sex drive. But mind peace is so important. I was ready to collapse !! Zoloft helps your neurotransmitters. It is not our fault. Just brain "malfunctioning"."

9 / 10
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56 Report
  • traciii
  • Taken for 2 to 5 years
  • November 25, 2014

For Panic Disorder "After trying just therapy for panic disorder, major depressive, and general anxiety I finally gave in and starting taking Zoloft. THANK GOD! I haven't had a single panic attack in 5 years when at one point I was having them up to ten times a day! I have had zero side effects. I also took it through pregnancy. I'm 28 and I'm fine with taking Zoloft forever, living without anxiety is just amazing!"

10 / 10
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217 Report
  • MMano
  • December 13, 2018

For Premenstrual Dysphoric Disorder "Wish I had started this years ago! I was terrified to start medication, it was the last resort after trying natural ways to deal w/ PMDD for years. Every month, I'd have serious depression/ anxiety/ uncontrollable crying spells/ want to leave my family the 4 days prior to period. As soon as my cycle started, I was completely normal. I thought it was just me, until I started tracking and was diagnosed with PMDD. I resisted using medication thinking I could handle symptoms on my own. Mistake. I started taking zoloft ONLY during my luteal phase and the very first month had relief! Since taking, my PMDD symptoms have almost completely subsided. I have not noticed any negative side effects. I was worried about diminished sex drive, but found that my sex drive has increased during the luteal phase since I'm not suffering from the effects of PMDD."

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  • AnneJay
  • Taken for 6 months to 1 year
  • April 5, 2017

For Depression "My original post was 10/2/16-had great results immediately on 50mg daily. I am able to hold down a full time job that I love, which was impossible prior to Zoloft. Rarely have anxiety anymore, my relationship with my husband has improved, and the constant "internal storm" is gone. At 51, I finally feel HAPPY!!! Keep trying everyone!"

10 / 10
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174 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.