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Pancrelipase User Reviews & Ratings (Page 2)

Brand names: Creon, Zenpep, Pancreaze, Pertzye, Viokace

Pancrelipase has an average rating of 6.7 out of 10 from a total of 80 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Pancrelipase

  • LeeAnn
  • January 23, 2022

Creon (pancrelipase) for Chronic Pancreatitis "I have been taking Creon for about 3 months now and before I started the med I wouldn't eat till a 11am but now it's like if I don't eat every few hours I feel dizzy and lightheaded and I get the shakes real bad and most of the time I feel weak and sleepy and my stomach is still upset time to time does anyone else have theses problems please let me no if you have or are. TY"

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  • scott
  • Taken for 1 to 6 months
  • November 12, 2023

Creon (pancrelipase) for Chronic Pancreatitis "I have a rare autoimmune disease that's given me chronic pancreatitis. I have stones halfway up my pancreas duct and it's dilated. I have to have 4 or 5 hospital visits for stents and to try to get the stones out. Then my head of pancreas removed. I am 53 and have been sick ever since I was in a coma 5 years ago. Didn't know why. Now I do. So Creon has helped me big time. I'm only just diagnosed and have been sick daily for that time. Pains, toilet issues, you all know the symptoms. If I don't take Creon 25000 2 or 3 with a meal and 1 with a snack, I get all the badness back. I'm getting it for cheap as I'm in Australia and we have great Medicare here, so no insurance needed."

10 / 10
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4 Report
  • Lorra...
  • Taken for 2 to 5 years
  • June 29, 2020

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "“I have been persevering with Creon on and off for three years now after Whipples surgery. Every time I started it back on me diarrhea was actually worse. This medication did absolutely nothing to help even with increasing in dosage. I continued to have frequent explosive diarrhea problems. I am told to keep taking it and worry that by not taking it it will do more harm."

1 / 10
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19 Report

Frequently asked questions

  • motguy
  • Taken for 6 months to 1 year
  • June 5, 2019

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "Whether it was the medicine or not, I had abdominal pain after taking Creon for 2 months. I cut the dosage back, had more tests run on abdomen, which showed nothing. Have been taking a dosing capsule of 24,000 units with each meal since February and have had no side effects. No more runny stools or frequent trips to the rest room. Have an appointment and lab work later this month."

8 / 10
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  • wayner
  • Taken for 1 to 6 months
  • January 13, 2023

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "Creon has done nothing to relieve my symptoms. I am still suffering from bloating, feeling like vomiting all day headache, and I have lost 30 lbs in three months. I am going to ask the doctor to switch me to Zenpep. Creon has a 50% approval whereas Zenpep is 74% so I'm hoping it will work for me."

1 / 10
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Are you taking this medicine?

  • Edwardv
  • Taken for 2 to 5 years
  • June 15, 2023

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I've been on Creon 3 x 36,000 lipase units every meal for three years without any issues until recently. About 5 months ago I started having explosive diarrhea, up to 6 times a day. I stopped taking it for a few weeks and got better. I started back slowly with 1 x 36,000 lipase units and over the course of 2 weeks I increased back to 3 pills with meals. Everything was fine for about 3 weeks now my diarrhea is back. Yesterday I scheduled an appt. with my doctor and I am going to stop again."

6 / 10
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  • FlorA
  • Taken for 1 to 2 years
  • October 18, 2023

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I've taken Creon 36,000 units per meal for almost 2 years. It's overall good, but like all meds, there are side effects (headache, blurred vision, sore throat). I have an autoimmune condition, and my sore throat and dry mouth worsened (so not sure if caused by Creon or the AI condition). For me, it works best to take it in the middle of the meal. If I take it before eating, it causes irritation on my throat. I also think it works best to get the lower dose and use it according to the size of the meal; so a single one for snacks, and can double if full meal. I hope my review helps someone. Wishing good health to everyone here!"

8 / 10
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  • Sick...
  • March 15, 2016

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I had immediate problems when I started taking this medication. Honestly, I thought it was a placebo, because I had all of the symptoms that caused me to take the med in the first place. Definitely did not work for me."

1 / 10
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30 Report
  • lg06
  • Taken for 1 to 6 months
  • May 13, 2023

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I was told to take this as lipase was not enough (was discovered through diarrhea/loose stool, greasy.) This has made me feel worse! Abdominal cramps, sometimes bad, and inability to empty bowels enough to safely leave the house for 3 hours. Huge all-over body bloat. I quit it and in 2 days a friend asked me if I had lost weight, even my face looked slimmer, and I thought bam! Water retention, oh! The pain from this is not worth it. Are the others on here mentioning anxiety? Yes!! So bizarre this could cause it but I've had some pretty bad days, had to even take Benzo, no reason why...but perhaps this! What a shame So many bad reviews here, what can help us??"

3 / 10
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  • King...
  • March 30, 2012

Creon (pancrelipase) for Cystic Fibrosis "I'm a 42 year old male with cystic fibrosis. Survived until 38 with no medication but constant diarrhea. Could not tolerate fatty foods or alcohol - made me very nauseous and big weight swings. Creon has stopped all this completely and life is much happier and healthier. The little Creon carry pack makes taking creon 25,000 with meal easy. Very happy."

10 / 10
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37 Report
  • Anonymous
  • January 6, 2017

Zenpep (pancrelipase) for Chronic Pancreatitis "This medication works well for me and I had no side effects. The monthly cost is so expensive!! $1875.72 monthly without insurance! With little to no help from the pharmaceutical company. When my insurance will pay for it it's $240. Monthly"

10 / 10
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21 Report
  • Cheers
  • Taken for less than 1 month
  • May 12, 2021

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I'm on day 3. I feel very foggy on this. A little dizzy, unable to focus, it's like I have a bit of tunnel vision. I'm assuming it's the fillers used (In the ingredient list on the professional information for Creon says one of them is PEG, which I avoid). I will not continue taking this. It's likely I'll go back to OTC pancreatic enzymes, I didn't feel like this on them at all but only accepted the script because my copay was less than OTC."

1 / 10
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10 Report
  • Nana
  • Taken for 1 to 6 months
  • February 6, 2023

Zenpep (pancrelipase) for Pancreatic Exocrine Dysfunction "I was experiencing diarrhea 6 or 7 times a day, had cramps, and a rock-hard stomach and bowels. I had sleeve surgery 8 years ago and my gallbladder was removed about 30 years ago. I was prescribed Zenpep one month ago and feel like a new person. Bloating, stomach pain, and diarrhea are gone as long as I take it with every meal. If I eat without taking it the symptoms return. I am glad I have good insurance as this medication costs $1500 monthly, and I pay $30 for 2 months. It really does work well for me."

10 / 10
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  • Bee
  • Taken for 1 to 2 years
  • July 19, 2021

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I’ve been using Creon on and off for two years and right now I’m up to three 24,000 capsules before each meal but I still have horrible, horrible, horrible cramps and diarrhea. I’m going to my third gastroenterologist tomorrow and hope fully he will have some answers! This is no way to live."

2 / 10
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  • 422
  • Taken for less than 1 month
  • November 19, 2021

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I had whipple surgery 8 months ago. I was doing fairly well and then started having bouts of diarrhea. Diagnosed with Exocrine pancreatic insufficiency (EPI). Just started creon. Stool is loose but not diarrhea. I am lethargic after taking for a couple of days. Anyone else experience lethargy? I'll update as I proceed with using."

6 / 10
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  • Blanca
  • Taken for less than 1 month
  • February 6, 2020

Zenpep (pancrelipase) for Chronic Pancreatitis "Started using Aenpep. No side effects but honestly it does not work. I been in pain ever since I started taking it. I take it during each meal and I am in pain. Pertyze is what really works for me but my insurance does not want to cover it :( it sucks that we paid too much for insurance and I have to beg for my meds. Actually is the only one I take. I eat well - I gave up sweets and red meat, coffee, not to many carbs but I hurt. I go on liquid diets for 3 days if not more. As soon as I eat there is my pain again with this pills."

1 / 10
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  • Christi
  • Taken for 1 to 6 months
  • October 24, 2021

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I was diagnosed with inoperable Stage 4 pancreatic cancer. They started me on 12000 mg Creon, did nothing but make me feel worse. Then the oncologist upped the dosage to 36000 mg, 2 with meal, 1 with snack. Still explosive diarrhea and I had already lost 30 lbs. then the oncologist tripled my dosage and I spent 8 hours on the toilet every day (no exaggeration). I stopped taking it and I’m actually doing better. It’s not worth the sacrifice of my quality of life. Never will I take it again."

1 / 10
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  • adlis...
  • Taken for 10 years or more
  • June 7, 2012

Creon (pancrelipase) for Cystic Fibrosis "Out of all the synthetic pancreatic enzymes I have taken Creon20 is the most helpful so far but I find its best just to not eat fat. Also a normal person needs only 30 calories of fat a day so if you have cystic fibrosis keep this in mind. "

10 / 10
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25 Report
  • Memee
  • Taken for less than 1 month
  • July 3, 2023

Creon (pancrelipase) for Chronic Pancreatitis "I started Creon and felt great for 2 weeks, no side effects... and then I had swelling in my lower legs, ankles, and feet. The doctor told me to stop taking it. I am truly disappointed - less bloating, gas, no pain at all. I hope he has something else in mind."

10 / 10
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  • Ron...
  • Taken for 2 to 5 years
  • December 9, 2020

Zenpep (pancrelipase) for Pancreatic Exocrine Dysfunction "Using Zenpep has made a significant difference in the way I feel having Pancreatic Exocrine Dysfunction (PED). Without this medication I have a difficult time getting through a day without gastric issues."

9 / 10
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  • Hmc
  • Taken for 6 months to 1 year
  • February 13, 2024

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "After reading all these reviews, I guess I'm the lucky one. Had a huge back surgery, 3-day surgery, every other day for 12 hours. Happy to say the back surgery worked great, less pain now than I've had in about 30 years. However, it turns out that massive of a surgery creates issues in your body that you've never had. I began having explosive diarrhea 4-6 times a day, bloating, and horrible gas and flatulence! My doctor said she thought I had EPI and put me on just 3000 units of Creon, and for the first week, it did absolutely nothing! My doctor told me to keep taking it, one before any and all snacks and two before meals. Finally, after about two weeks, I began feeling some relief. Then, thank god, in about one more week of taking Creon, all the other symptoms were gone, and I can honestly say I've had the most regular, normal stomach functions I've had since my surgery 3 years ago! Sorry for all the issues so many of you on here have had, but for me, so far, Creon is a miracle drug!"

10 / 10
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  • CJano
  • Taken for 1 to 2 years
  • July 25, 2021

Creon (pancrelipase) for Pancreatic Exocrine Dysfunction "I have been taking 24,000 units of Creon 3x for meals and 1x for snacks for about a year. Initially Creon seem to work without noticeable side effects. Now, I have developed functional dyspepsia including weight loss, bloating, and hard stomach. The dosage was increased however I still am not able to gain weight. I am very disappointed with this medication."

4 / 10
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  • Reen
  • Taken for 10 years or more
  • January 22, 2024

Creon (pancrelipase) "I have been on Creon for 15 years. I take 22+ tablets a day and live on a low FODMAP diet. I never eat beef or lamb as I cannot digest them. If I don't have tablets with a meal, I am in agony and end up living in the bathroom. I am thankful for the tablets. They have helped me to live."

8 / 10
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  • mammers
  • April 14, 2008

Creon (pancrelipase) for Cystic Fibrosis "Creon has helped my little three year old cousin. She was born with cystic fibrosis and she doesn't understand what it can and what it is doing to her! She is a heathy little girl that is going to survive this birth defect!"

10 / 10
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  • Lea
  • Taken for less than 1 month
  • July 4, 2021

Creon (pancrelipase) for Cystic Fibrosis "Was given this med due to chronic diarrhea PCP wanted to see if would help with it. The same night I took it, I started having horrible mid to upper back pain then pain along the left side that went into the abdomen. I went to ER and told them about meds and they ran test and was unsure. I got labs b4 I left showed infection in blood so now being treated for this rare infection with high dose antibiotics . Make sure to get labs for this since virus can be over looked if there not familiar with Creon"

1 / 10
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5 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.