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Paliperidone User Reviews & Ratings

Brand names: Invega, Invega Sustenna, Invega Trinza, Invega Hafyera

Paliperidone has an average rating of 4.5 out of 10 from a total of 587 reviews on Drugs.com. 32% of reviewers reported a positive experience, while 53% reported a negative experience.

Reviews for Paliperidone

  • Anony...
  • Taken for 1 to 6 months
  • June 21, 2021

Invega (paliperidone) for Schizophrenia "I have been diagnosed with bipolar with psychosis in June 2020. I got 2 loading doses of invega then two others doses in two months , total of 4 doses. Now I am 10 months since the last dose still suffering from weight gain ( 20 Kg ), erectile dysfunction with numb penis and shrinkage, less semen volume. This drug is a awful , DO NOT TAKE THIS MEDICATION AT ALL Unfortunately , I did not have the choice to accept or refuse the drug because I was admitted to hospital at that time , they took the consent from my parents who did not know what this drug is .... This is a post for humanity, please do not use this drug, it ruined my life totally."

1 / 10
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  • Phyc...
  • Taken for 6 months to 1 year
  • November 21, 2020

Invega (paliperidone) for Schizoaffective Disorder "If you are looking for the worst time of your life this is the medication for you! Do you want to gain 100lbs? Lose all your friends and be made into a vegetable? If so Invega will do the job. Don’t take this, its terrible you will gain weight, everything nice will gone from your life, you will feel sick and foggy all the time and your life will basically be over. It reduces you to like a fraction of the person you should be and its messy and unpleasant. No one should take this."

1 / 10
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  • Maryc...
  • April 19, 2021

Invega (paliperidone) for Schizophrenia "Do not take this drug! I was given two injections and don't want anymore, I'm severely depressed because of this stupid horrible drug, cannot concentrate, it literally ruined my brain caused severe brain damage, DO NOT TAKE THIS DRUG! THESE COMPANIES SHOULD BE SUED!"

1 / 10
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Frequently asked questions

  • Dolla...
  • Taken for 1 to 6 months
  • November 5, 2020

Invega Sustenna (paliperidone) for Schizophrenia "I got this shot by doctors that had no clue and I had no idea what I got. This shot gave me lower IQ, worse memory, slower thinking, loss of emotions, depression so to say, high level of prolactin, erectile dysfunction, no sperm at all and also anxiety. My memory used to be extremely good and also I had high IQ, but now I have a hard time to remember things and my IQ dropped significantly on IQ tests. Im going to report them to the police and throw a law suit. All of this by a shot I shouldn't have got at all. Ban it please and don't let others go through the same hell as I did."

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  • Grant
  • Taken for 1 to 6 months
  • May 23, 2018

Invega (paliperidone) for Schizoaffective Disorder "My son started Invega and the drug made his symptoms worse. He couldn't sleep he became very agitated. He had hospital admission after hospital admission. I am sorry to say he killed himself about three months after starting this drug. Please don't let anyone you love start this drug, it is a very bad drug."

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Are you taking this medicine?

  • Ira
  • Taken for 1 to 2 years
  • November 7, 2020

Invega (paliperidone) for Schizophrenia "Put on thos medication for two years. I don't hear voices or anything, but yet I was diagnosed schizophrenic. Made me forget words, feel stupid, impotence, erectile dysfunction, sexual problems overall decreased ambitions, decreased confidence, felt swollen, my life turned upside down. Got off the medication two months ago and increasingly feel better. I hope all the side effects wear off and I go back to normal. I hope."

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  • TheNu...
  • December 31, 2020

Invega Sustenna (paliperidone) for Schizophrenia "This drug rendered me bed ridden with no interest in life. I went from being an opinionated funny guy that could read your emotions and make just about anyone laugh, or at least smirk. I've always been very emotional and this drug sucked my soul, will to live and emotions right out of me. I'm left an empty shell of who I was. This drug is referred to as a chemical lobotomy for good reason. It shuts down all free thoughts, the voice in your head, your conscience disappears. With nothing to say, no interest in anything, no thoughts, no emotions, you as a person just about stops existing. No feeling of gratitude, accomplishment, satisfaction. Your thought process and basic decision making skills are destroyed. I've been off this drug for about 5 months now and I'm not seeing too much relief. The fear of "being like this forever" is a constant fear that never lets up, since this isn't a life this is merely existing. My plea and advice to you? Stay away from this medicine."

1 / 10
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More FAQ

  • Solar
  • April 14, 2021

Invega (paliperidone) for Schizophrenia "This is the worse medication ever. I was 120lb when I started on this and I gained 80 lbs. My boobs went up from A cup size to D. It has been so hard to lose the the the weight. I don't take the meds anymore and I'm still trying to lose the weight and it cost me other health problems on top of this. I would not wish this this medication for anyone. I did not feel better on it at all. In fact I felt dizzy and was sleepy and all I wanted to to do was eat. I repeated myself constantly while on this med. I blame the manufacturer s for all the damages."

1 / 10
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  • Anya
  • February 1, 2020

Invega (paliperidone) for Schizoaffective Disorder "I’m currently writing with trembles in my hands and muscle stiffness. I had a nervous breakdown and classified bi-polar NIGHTMARE BEGAN. I have extreme paranoia , lost my job because Invega destroyed my hand coordination, TD, (I believe I have permanent brain damage), sexual dysfunction, muscle stiffness, tremors in my whole body, hands shaking, face twitching, curling fingers, I can’t hold down food, severe anxiety, depression, suicidal, anti-social, no emotions, removed from relationships, no periods infertile at this point, no sleep in 3-months, pacing, blurry vision, absolute chemical lobotomy - fear of body deteriorating. 39 years old hard to find the energy just to stay alive. Everything in my body is dry. I’m a nervous wreck. Detoxing: I was trying to restart body- No change in 2-months. Instead have early signs of Parkinson’s. "

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  • SadCa...
  • Taken for 1 to 2 years
  • April 17, 2021

Invega Sustenna (paliperidone) for Schizoaffective Disorder "I was prescribed Invega Sustenna on my 5th hospital stay for bipolar and schizoaffective episodes. I wasn’t responding to the oral medications and I have compliance issues with taking oral meds anyway. Like most people who have already commented, my experience with this drug have been horrible. Yes, it stopped the hallucinations but it has robbed me of my emotions, I feel flat all the time, I gained weight, my hair fell out, I lost my sex drive and my ability to orgasm, I have anhedonia and avolition, I cannot socialize anymore, I can barely contribute to a conversation, I’m barely caring for myself (not cooking, not cleaning)....I am like a child. This medication is terrible in my opinion, I would not recommend it. I’d rather live with the occasional hallucination, then all of the side effects Invega has caused."

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  • Deano
  • Taken for 1 to 6 months
  • January 5, 2019

Invega (paliperidone) for Schizophrenia "I got diagnose with schizophrenia and bipolar in the hospital. I was taking respidone which was helping me a lot but then I start taking invega. This medicine has ruined me. All of the things that I've loved doing now sucks. I was on it for 4 months but I've been off of it for 3 months now but I'm still dealings with side effects. I can't sit still or lay still. I'm always tired my tongue is always numb my speech is off. I can't have a simple conversation I can't sleep at night. I hate waking up in the morning, my thoughts are all confusing and I feel weak. My body is really sensitive......I just miss the old me."

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  • 123
  • Taken for 1 to 6 months
  • June 4, 2020

Invega (paliperidone) for Schizophrenia "NIGHTMARE! I do not recommend this drug. I was taking it for 6 weeks (3 weeks to get me on 900 mg and 3 weeks to get me off). Terrible vivid nightmares that seemed more real than reality. I was wondering if I am dreaming or is it real all the time. My mind was empty. My muscles were in pain, I couldn't properly move my body because of "hard" muscles. I had a feeling of being pregnant - smell and taste changed, I had contractions and I produced milk. Only when this happened doctors decided to put me off that drug. Thank God for body side effects, because doctors don't take serious when you tell them that a drug is bad for mind, emotions etc."

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  • Skano
  • Taken for 2 to 5 years
  • March 20, 2021

Invega (paliperidone) "I had pychosis for a week and was put in ward and the idiots diagnosed me with schizophrenia . Made me have invega injections for 2 years . Off it now I told them no way no more . Invega ruined my life and has given me permanent brain damage ."

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  • Dade
  • Taken for 1 to 6 months
  • June 30, 2019

Invega (paliperidone) for Schizophrenia "I started taking this medication for 3 months after I was diagnosed with schizophrenia and it has ruined my life. I now have trouble speaking, I'm always anxious, I can barely concentrate on anything, I'm depressed and sleeping a lot, and I no longer get erections and have trouble producing semen. I have been off of it for 2 months and I'm still dealing with the side effects. This is the worst thing I have ever been on and I wouldn't recommend it to anyone."

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  • Jesus
  • Taken for 1 to 6 months
  • November 15, 2019

Invega (paliperidone) for Schizoaffective Disorder "I'm so depressed on invega that I cry multiple times a day, can't maintain any friendships, too tired and demotivated to work out or play my guitar like I used to. I lay in my bed every day no motivation for anything"

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  • Remi
  • October 14, 2019

Invega Sustenna (paliperidone) for Schizophrenia "I took 6 injections over a 6 month period. I didn't notice much in the first couple of months. It helped with the paranoia, I still heard voices to a lesser extent. Around the 5th month, I had noticed I gained 50 lbs (115 to 165) It happened so rapidly. I also began to lactate. That was all horrible but the worst of it was the severe anhedonia. They wanted to slowly taper me off the injection but I refused to take any more after the 6 month period. I felt mentally slower. I got no pleasure from listening to music, or watching TV. I stopped laughing. This is just my personal experience, but if you look up this medicine you will find there are many people that have gone through a similar experience. It's been 14 months since my last injection and I think I have mentally fully recovered. I think this drug is too potent. I am almost certain it gave me some sort of brain damage. One of the biggest regrets of my life is taking this drug, I was better off before."

1 / 10
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  • bobby...
  • Taken for 1 to 6 months
  • March 25, 2021

Invega (paliperidone) for Schizophrenia "I was sent to the hospital this January, with a plan of suicide after a big meth bender where they basically said, "stop using drugs and stop bothering us" (been admitted to psychiatric care multiple times). My GP became infuriated with how they just simply dismissed me and put me back on Invega. Within a week, my mood improved majorly, my tendencies left, I haven't been using illegal drugs, my life has completely turned around. I have zero sex drive, but I'm back at Uni studying my Bachelor of Science. My parents are super proud of me, my attitude has changed, I'm happier, I have accepted my shortcomings, and finally have a goal in life. I think zero sex drive is better than cutting stuff into my face."

9 / 10
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  • Ethan
  • Taken for 1 to 6 months
  • January 31, 2020

Invega (paliperidone) for Schizophrenia "So, I was high energy and a lovely person before taking this drug. After my second shot of 234mg, I became so tired and depressed like all the life had been sucked out of me. No longer bubbly and energetic I would just lie down all day with no energy to move. Very sad. Very very sad."

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  • Momof...
  • Taken for less than 1 month
  • April 3, 2018

Invega (paliperidone) for Schizophrenia "My son (23 year old) got the Invega shot. It's the worst thing ever. It's making him cripple, still hearing voices, shuffling when he walks, insomnia. This drug needs to be taken off the market I am going to write to the FDA it's very expensive and does nothing to help. Where are our tax money going? Why isn't there a cure? The insurance companies are blood suckers. The poor mental health patients cannot get any help. I am so sick and tired of this disease right now I just want my child back."

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  • Anonymous
  • September 7, 2019

Invega (paliperidone) "Worst experience of my life. I have absolutely no thoughts and no emotions. The doctor that gave this to me said it’d only last a month. Well he lied. It lasts 300 days. I’m hoping with all my heart I will get better.."

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  • CianR...
  • Taken for 1 to 6 months
  • August 9, 2021

Invega (paliperidone) for Schizophrenia "Tricked into this at the mental ward because of psychosis caused by Bipolar 1 and I absolutely don't like it. I am unable to think and retain information, I get no joy out of music, food, books, or TV anymore. I am a visual artist who no longer has inspiration. I can barely remember my characters or their stories. I can't think or write with any regularity. I can no longer laugh regularly or feel most emotions. It has been a miserable experience. I can't imagine what kind of sadism it takes to create a drug that makes people so empty inside. I am missing memories and all kinds of pieces of my old self. I can deal with not having a sex drive. I can't deal with the rest of the side effects. I want my brain back."

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  • Eano
  • May 17, 2019

Invega Sustenna (paliperidone) for Schizophrenia "Worst experience of my life. I can't describe all of the side effects I had on invega Sustenna in 1000 characters, but my mind was disturbingly blank on this medication. It was as if all of my conscious thoughts were gone. I gained 25 pounds even though I just got the initial dose & lost muscle. My delusions did go away so it worked for that, but it felt like it was because my thoughts stopped. I've gotten 4 sprains and one pulled muscle since I got injected with this poison at the end of August last year. My skin started flaking off and and my hair was falling out. I couldn't feel any emotions. I was unable to orgasm for the first month. There were more side effects, & I don't think I fully conveyed the desperation I felt on this medication. I would like to let people who have gotten on it & hate it that there is hope & you will get better - once you are off it"

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  • Unicorn
  • April 13, 2021

Invega (paliperidone) for Schizoaffective Disorder "I've been on invega for 3 years. The beginning was bad. I had so much energy I couldn't sit still or get comfortable. I gained weight but it got better. I started to see the benefits for example less tension and edginess, better decision making, sleep improvements, and feeling less scared and paranoid. Then I got diagnosed with high levels of prolactin. It has been over a year and they still can't get it in control which means I'm always itchy and fat. Now I was diagnosed with pre-diabetes because of meds. I was told to eat right and exercise everyday for the rest of my life. And then he laughed!! It has been about a month since pre-diabetes diagnosis and I have only lost 1kg. That's with healthy eating and exercise. My dr thinks the benefits still outweigh the risk so there constantly pushing the drug on me but I'm itchy, pre-diabetic, and fat."

6 / 10
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  • Nseyet
  • Taken for 1 to 6 months
  • November 28, 2018

Invega (paliperidone) for Schizoaffective Disorder "I was forced to take invega after a spiritual emergence was diagnosed as schizophrenia, bipolar, and schizoaffective disorder. I had the initial dose of 256mg I believe, then 150mg for four months. My last shot was in aug 2018. By the second shot my thoughts had stopped. I could no longer think. It shut off my consciousness. My memory and retaining information has been effected. I developed anhedonia. I can no longer feel any emotion. I have no libido or menstrual cycles. I haven't had an appetite in 4 months. I have no desire to eat or get pleasure from it. I have insomnia. I believe this medicine has caused brain damage. Other drugs have reduced or no effectiveness such as cannabis, nicotine, caffeine, alcohol and sleep medication. This drug has a half life of 25-49 days. So its gonna take at least a year before it is completely out of my system."

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  • Kano
  • May 14, 2019

Invega (paliperidone) for Schizoaffective Disorder "It's been 3 years since I took Invega but I still think about it often because I have never been as depressed as I was on Invega. I would literally cry upon waking because I couldn't bear being conscious. I was sleeping ~13 hours a day for a few months. It made me catatonic a few times as well. I was so depressed there were times I couldn't lift my head or stand up or even talk. It was an actual nightmare and my psych insisted it was just initial adjustment side effects, but I have never been on a medication that harmed me as much as Invega. I would have taken the psychosis over the Invega any day. I stopped taking it without permission and I kid you not--the next day, I felt normal. I physically couldn't get out of bed and my limbs felt like lead; it was ridiculous. I was in such a dark dark place and started giving away my belongings, but stopped almost immediately once I stopped the medication."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.