Paliperidone Pregnancy and Breast Feeding Warnings

Paliperidone is also known as: Invega

Overview

If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Paliperidone while you are pregnant. Paliperidone is found in breast milk. If you are or will be breast-feeding while you use Paliperidone , check with your doctor. Discuss any possible risks to your baby.

Paliperidone Pregnancy Warnings

Paliperidone has been assigned to pregnancy category C by the FDA. Animal studies have revealed increased pre- and post-implantation loss, a slightly decreased number of live embryos, and decreases in serum testosterone, sperm motility and sperm concentration. There are no controlled data in human pregnancy. Use of first generation antipsychotic drugs during the last trimester of pregnancy has been associated with extrapyramidal symptoms in the neonate. Paliperidone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Patients should be advised to notify their physician if they become pregnant or intend to become pregnant during treatment with paliperidone. The extrapyramidal symptoms are usually self-limited. It is not known whether paliperidone, when taken near the end of pregnancy, will lead to similar neonatal signs and symptoms.

Paliperidone Lactation Warnings

Paliperidone is excreted into human milk. The manufacturer recommends that patients should be advised not to breast-feed an infant if they are taking paliperidone.

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