The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Compare all 29 medications used in the treatment of Fibromyalgia.
Reviews for Savella to treat Fibromyalgia
Review by Amanda T. (taken for 2 to 5 years):
I first started taking Savella in May of 2009, it had not been on the market long. I used the starter pack from my doctor and noticed positive results right away. Savella interacts with a lot of other medications, so I have to be very careful, especially with serotonin syndrome which I did have symptoms of after taking Savella and Tramadol together. I do get the night sweats and remember more dreams and even have lucid dreams now, both otherwise no other negative side effects. Savella does cause somewhat rapid weight loss for me (1-2lbs a week, but I have it to spare). Decreased appetite as well. It really helps control my fibromyalgia symptoms, Savella is my miracle.
19 users found this comment helpful.
I have taken most everything on the market and we started to think I had been misdiagnosed. My doctor was at a point where she was beginning to think the same thing. Savella was my last hope. I began taking the titration pack with no marked change so she increased the dosage and so far I feel better than I have in a long time. The only drawback (other than decreased sexual appitite) is the cost. My co-pay is $45. It may not seem much to some but when I am taking 9 RXs a month it is costly but worth it.
34 users found this comment helpful.
I was put on Savella shortly after it came out and was on it for 3 months and my blood pressure rose. My doctor took me off of it and added blood pressure medication and I was put on Neurontin. Neurotin did not do anything for my fibromyalgia, I was constantly in pain. Six months ago, I went to my doctor and stated I wanted to try it again, because it had worked before and we had added a blood pressure med. I was depressed and hurting. I told her I did not want to be on narcotics all the time to control the pain. I have been on it now for about six months, we are watching my blood pressure closely and all has been good. It has helped with my IBS, I have lost almost 40 pounds because I feel good and can move and do simple things again.
50 users found this comment helpful.
Review by Victim of Pain (taken for 2 to 5 years):
I'd been treated for fibromyalgia for close to a decade before being prescribed Savella. I wanted to try Lyrica but my Dr said it wasn't a good option for me, not wanting to risk my liver & other side effects of swelling. Savella worked very well for muscle pain. I actually went from Cymbalta to Savella with less side effects. However, after 2 years I could no longer stand the side effect of severe sweating.
36 users found this comment helpful.
I found Savella helpful for my fibromyalgia. I was on 50 mg x day. I was probably on it two years when I began to get high blood pressure, palpitations, drenching sweats and a general feeling of unrest. I stopped taking it and all side effects began to leave. I could not tolerate taking it anymore. I did not think it was really doing much until I stopped taking it and as it left my system I began feeling flare ups of fibromyalgia symptoms. I find I am sensitive to Neurontin, Lyrica, prednisone, many medications.
41 users found this comment helpful.
I have been taking Savella for about 4 weeks, 2 weeks at 50mg morning and night and have been having lots of side effects, almost flu like symptoms. Weakness, shakes, lightheadedness, cold, then hot. I have been reading lots of reviews, because I didn't think it could be this medicine, but I guess it can be. I work graveyards and I think I might try 50 mg in the morning and 25 mg at night and go from there. I was on Lyrica for 9 yrs and it was so expensive and the Savella is half the copay Lyrica was. I'm not ready to give up on it yet, but I am so hot all the time, but the weight gain from Lyrica was the reason I decided to try Savella since my insurance will cover now. I'm hoping for the best. Good Luck.
21 users found this comment helpful.
I visited a rheumatologist the first time about 3 or 4 months ago because my osteoarthritis appeared to have worsened over many months. I had gone to my family doctor but he couldn't understand the reason for my pain becoming so severe with my osteoarthritis. I was frustrated as a nurse because I walk a lot at the hospital. The pain was more than I could stand, starting at my lower back, down my right hip, and on down to my right leg above my knee. I
cried numerous times with this discomfort. I could tolerate the pain with my swollen knuckles, loss of cartilage in the knees or any other pain, but NOT the back pain. I have been taking Savella & the back pain is significantly reduced! I do have heavy sweats and I remember my dreams.
42 users found this comment helpful.
I've been suffering with overall pain for approximately 10 years now. I went to the doctor 9 years ago who said he thought I had fibromyalgia, and I would have this pain for the rest of my life because there is no know medication that would help. Then a month ago the pain was getting so bad I couldn't sleep. I decided to go to a specialist who told me I do have fibromyalgia. I was given a sample of Savella, and it worked right away. I've been taking it for almost a month now and I have not felt this good for years! After reading all the side effects everyone is having has scared me. I don't want to stop taking Savella and get all that terrible pain back. I guess I better count my blessing and enjoy for now.
60 users found this comment helpful.
This is a tough one. I've been taking Savella for not quite a year. I have no known side effects, taking twice daily x 50mgs other than slight drying but I take other meds that also could be suspect.
Here's my report. It mainly helped take the stiffness, pins and needles out of my knuckles in my hands for months BUT know that is coming back. I think my body is getting used to it and its not working any longer, at least not as well. My Doc and I talked about going to 100 mgs but have not.
I still have to take Vicoprofen for my Fibromyalgia. Nothing else takes the overall tiredness and pain away like that.
Even though its not my miracle drug I like it enough to pay my $45 monthly script for it.
34 users found this comment helpful.
I started Savella 2 months ago for Fibromyalgia, I also have DDD, a C-spine fusion from 2-6, chronic spondylosis, sciatica, and migraine. I used 2 titration packages, using the same dosage for day one out of each package before moving to the next day, etc. That way it prolonged the rising of levels. I had been on Neurontin for many years and even though it helped tremendously for a long while, I started having pins and needle feelings in my legs, abdomen, etc. that an increase in dose didn't help. I still have nausea and a tired feeling, but believe some of it might be due to decreasing Gabapentin as I went up on Savella. Having said all of this, I am not having nearly as much pain as before!
37 users found this comment helpful.
I started Savella a little over a month ago and had not experienced any side effects until the last two weeks. Palpitations/ elevated resting heart rate and right sided headaches, which I did not realize were due to this medication because I didn't experience any initial side effects. Overall muscle pain has been greatly reduced, energy increased. Bummed out that I may have to stop due to the new side effects.
27 users found this comment helpful.
Review by CS Drenk (taken for 6 months to 1 year):
I have had a daily chronic migraine on top of the fibromyalgia since November 1999 along with several other problems. I have been on a LOT of different meds over the years. I started taking Savella in October of 2012 and after I had my dose upped to 100 mg 2x daily I realized one day that I was having a bad migraine. I then realized that I had been having many more good days than bad days and very few days spent laying in a dark room praying for overwhelming sleep. I actually have had migraine free days! My mood has been a little better, overall pain is somewhat better and I have had no side effects. So overall I consider it a success. I also still take Cymbalta, Neurontin, Topamax, Oxycodone and a couple of others. Good luck!
23 users found this comment helpful.
I like Savella better than Lyrica. It works well for me, even though I'm in a physical job. I still hurt, but it's better than nothing and there aren't really any side effects. When I first started it, I did tend to get hot really fast, but that has gone away.
34 users found this comment helpful.
After two months on Savella, I feel like I have gotten my life back! Like others, it hasn't really helped with the neck pain, but all of my other pains have virtually disappeared. I did start even slower than recommended taking a full month to reach the recommended dose of 50mg 2 X day. Side effects include brief nausea 30 minutes after I take a dose, but try to always take with food and this helps. The sweating is bad, but not unbearable. Will see how it goes in the summer.
47 users found this comment helpful.
60% improvement in pain. 20 years with Fibromyalgia. 46 old female. 110 lbs. Have not seen one mention of thoughts of death or suicide. I experienced this at the 25mg 2X/day. Experience less depression and crying less though. Found
myself singing at times and noticed pain not as intense and it was normally extreme. Less neuropathy. Had night sweats. Feeling extreme cold especially hands and feet. Had no drive and wanted to just sit or lay down and not complete or attempt chores. Could not focus and forgetful.
I was on Elavil before that made me feel like a zombie but did help with mobility but not so much for pain. The doctor wants me off Savella in two days because of the suicidal thoughts. Says he can't help and sending to pain management.
20 users found this comment helpful.
I started taking Savella in Jan 2013 after years of other meds for my fibromyalgia. I've had it diagnosed since 1997. The worst side effect is the huge sweats. It was like going through the menopause again. Whew....and I've lost weight, which is a good thing. This sweating may be going away, since I only had three sweat attacks this week. Great med for calming down the fibromyalgia symptoms.
46 users found this comment helpful.
I started taking Savella about 7 years ago and still use it today. I started taking it in the drug testing phase before it was released to the public. I started out on only 10 mg 3 times daily and slowly built up to 75 mg in the morning and 50 mg at night. In the beginning the side effects were nausea, dry mouth and headache. After a couple of years..high blood pressure too now managed with meds. The benefits far outweigh the side effects. I ride my bike 3 miles a day and work 40 hours a week at a physically demanding job. Stick with it until the side effects subside. It will be worth it.
70 users found this comment helpful.
I have been on Cymbalta for one year, since G.P. thought I probably have Fibromyalgia. Helped with exhaustion and depression but not so much on pain. Saw a Rheumatologist last week and she confirmed the diagnosis and started me on Savella also. Have only taken 12.5mg for 4 days but my pain is already greatly reduced. No side effects yet, maybe a little bit of a "manic" feeling like I had too much caffeine.
49 users found this comment helpful.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Mar 13th, 2014), Cerner Multum™ (updated Apr 15th, 2014), Wolters Kluwer™ (updated Apr 3rd, 2014) and others. To view content sources and attributions, refer to our editorial policy.