Relistor for Opioid-Induced Constipation User Reviews

Relistor has an average rating of 6.4 out of 10 from a total of 22 reviews for the treatment of Opioid-Induced Constipation. 64% of reviewers reported a positive experience, while 36% reported a negative experience.

Relistor rating summary

6.4/10 average rating

22 ratings from 23 user reviews.

Compare all 8 medications used in the treatment of Opioid-Induced Constipation.

10		36%
9		14%
8		14%
7		0%
6		0%
5		0%
4		0%
3		5%
2		0%
1		32%

Reviews for Relistor

Gio
Taken for less than 1 month
August 17, 2018

"I have the most hardest time going to the restroom after taking norco / I would stay in restroom for hours pushing and pushing to the point blood would come out . I was super constipated I went to my doctor she gave me 150 mg 3x in morning 30 min before meal . Within 20 min I got horrible stomach cramps 1 hour after waiting I was able to poop like a normal person and a lot came out ! The stool was solid and didn’t have to strain and after I use restroom the cramps are gone ! It’s weird after taking meds I could feel everything being broken down and everything move down to my rectum sorry of that is TMI just wanted to share honest option ."

9 / 10

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118 Report

fathe...
February 5, 2019

"My father has terminal acute myeloid leukemia and his life is very much winding down. He's ingesting high doses of opioids on a daily basis which has caused him severe constipation. We didn't keep track exactly, but at one point he must've gone 3 weeks without a bowel movement and had the god-awful experience of vomiting feces due to a blocked bowel. Enemas did not work, nor did Colase, senna, milk of magnesia, miralax, etc. After being prescribed relistor, he injected himself with the shot for the first time a few nights ago. No exaggeration, it was maybe twenty minutes, no more than a half an hour after he took the shot that everything that had backed up inside him over the past several weeks let loose and came out. And I mean, everything. My mother and I were dumbfounded and could not believe that this drug worked so quickly, softening hard stool to mush and helping it out of him. It is a miracle product for cancer patients suffering from severe constipation due to opioid use."

10 / 10

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84 Report

SMano
September 18, 2019

"Relistor worked one time and one time only, but I did find something that works and could help a lot of other people. I take two full caps of Miralax into a full glass of water with one teaspoon of Metamucil and take a couple of Senna pills I do this process every other day and 90% of the time the next morning I go. It also helps eating Raisin Bran and fruit when you can. The Miralax and Metamucil I get at Walmart equate brand and CVS has a senate s CVS brand pills 180 for $23 which is the best deal. I bet that will solve the majority of people out there trying to figure this out I've been on opioids for 15 years and always had trouble even having a bowel movement when I was a kid so try this process good luck"

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48 Report

Frequently asked questions

Which drugs cause opioid-induced constipation?

James
Taken for less than 1 month
July 7, 2018

"I took my dose of relistor at 3pm by 11:15pm I started with the clean out. I thought it was done by about 1am but found out different and then got worried because by 9 am I was still on full clean out, the only thing no one said is that this takes 12 to 24 hrs to get out of your system."

10 / 10

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50 Report

Scott
May 21, 2020

"I've been on opiates for 20 years and have struggled with constipation. It seems to be getting worse all the time. I drink Milk of Magnesia throughout the day in an effort to produce a bowel movement. I've tried Movatnik and Linzess, Dulcolax, Miralax, Senna and Colace with no luck. Last night I went to the ER because I hadn't pooped in 5 days and I was in pain. They gave me Relistor and within 20 minutes I exploded, but it was just brown water and no poop. I had about 5 bowel movements, about every five minutes, but none produced any poop, just water. I also experienced cold sweats and severe cramping and back pain, which passed quickly. I was home in two hours after the injection and I didn't have any more bowel movements, so my problem wasn't solved. I'm still constipated and I'm afraid I might be obstructed or impacted. So I guess I'll be headed back to the ER when I can peel myself away from my heating pad and comfy bed. This is miserable!"

3 / 10

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32 Report

Are you taking this medicine?

Kimbo...
Taken for less than 1 month
August 24, 2020

"I just started yesterday, and literally 30 minutes after taking Relistor, I had a complete normal BM. I was so excited, I even called my mom to share the good news. I have suffered with severe constipation for years, taking opioids 10+ years. I will write again to let you know if it continues to work. I also feel like this may help me loose a bit of weight. I never eat, but never poop, so my weight stays same, because I never had BM’s. I am excited about my first results. Reading reviews, it seems like the Tablets work much better than injections."

10 / 10

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27 Report

poppy...
Taken for 2 to 5 years
October 4, 2018

"I have been on sustained release morphine for several years for chronic pain from MS and Fibromyalgia. I also have a neurogenic bowel and bladder from MS. I have to do a lot to make sure my bowels stay regular. Relistor definitely makes things easier. I can usually have a bowel movement with 1 shot although not always. The down side is sometimes it works too well and I have diarrhea for a few hours. The injections themselves are easy and relatively painless."

8 / 10

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35 Report

JB50
Taken for 1 to 6 months
April 2, 2017

"This medication is a lifesaver, for me. It works very well, with no side effects at all, for me. It was very expensive $1800.99 before insurance and the assistance card from the drug maker. If you have OIC like I do, try Relistor."

10 / 10

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40 Report

works...
Taken for 6 months to 1 year
March 20, 2018

"After injection within 5-15 minutes it will produce a movement and will clean you out completely. It can be taken anytime you want to take it. Very little side effects will make you a little warm for about 1/2 hour then passes. Works great for me but can be pricey without insurance."

10 / 10

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28 Report

Kmarie
Taken for 1 to 6 months
April 25, 2023

"I have been constipated for longer than I realized. I was managing but then 6 years ago my constipation controled my life. I’d be backed up for 3 weeks. I tried everything on the market. Relistor saved my life. I go every day now. Amazing."

9 / 10

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7 Report

Bandita
Taken for 1 to 6 months
January 30, 2020

"This medication is super expensive and does not even work. I’m unsure how it even got approved for OIC. At the time last year, Relistor was the only drug my insurance would pay for so I tried it. I have been on opiates for over 10 years, first in pain management and now Subutex for recovery. Even at the highest dose it did nothing and I still was only going once a week. On my new insurance I now take Linzess which works a bit better but I have to drink a cap full of Miralax as well. It also makes me super nauseous. Wish they could make a drug for this with less side effects."

1 / 10

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20 Report

Dennis
Taken for 6 months to 1 year
June 2, 2023

"I've tried all the meds made for opioid-induced constipation. I've had the problem for 10 years. I tried every prescription drug. I went to the E.R. once and they gave me a Relistor injection. Now that it's available in tablet format. The quality of my life has improved. I urge anyone to try this."

10 / 10

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6 Report

Jane
January 18, 2020

"I couldn’t believe how expensive this medicine was, so I figured it must be worth the bang. I have only been on pain meds a short while from a car accident. I have been taking this medicine for a few days now, and it’s done absolutely nothing. It certainly wasn’t worth $700. I am very surprised. I thought it would be a godsend. I finally went back to OTC medicine to help me. I won’t be buying another prescription of this."

1 / 10

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17 Report

Anonymous
July 24, 2019

"I have been experiencing OIC and have been using every otc and natural remedy available. The issue has been ongoing for several months. I took my first Relistor injection 5 hours ago without success.I added some suppositories, magnesium citrate and a fleet enema and expelled some gas and a few pellets of poop. Why have I not experienced a bowel motion and What can I expect with another injection tomorrow? This problem is totally incapacitating."

1 / 10

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16 Report

Kdmedic
Taken for 1 to 6 months
August 17, 2021

"I was given samples of Movantic and Symproic, both of which caused withdrawal of a level 6 on a scale of 1-10. Finally my insurance after 2 denials for Symproic stated a list of meds I had to try 1st, incl Amatiza, Lactulose, Linzess, Miralax, Senna, and at the bottom was Relistor. I had used all the above for years with no effect. Injured in a patient lift in 2003 I have 8 herniated discs, torn rotators, spinal stenosis, ect... I tried relistor 3 giant pills at 1 time. Researching I found take it 30 min before food or as I did initially, 6 hours after last food and last Oxycodone 15mg. Now I do as recommended, get up, no oxy (unless as usual I can't move from pain and I take 1/2 a 15mg). I take my 3 relistor 45 minutes before food. 2hrs later I'm on the toilet and I have less withdrawal than Symproic or Movantic. I thank my GI MD for pursuing this with verifications from my PCP as to previous meds. I give Relistor tabs 9/10 due to size."

9 / 10

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9 Report

Moggi...
Taken for less than 1 month
September 11, 2021

"With the first dose of resistor I had a moderate bowel movement with some straining. Later that day, I had severe nausea, stomach pain, and intense forceful vomiting. I was so dizzy that I could not stand up. These symptoms lasted for a couple of hours. The side effects were bad enough that I will not take another dose."

1 / 10

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7 Report

Bee
Taken for less than 1 month
January 11, 2021

"So I took a shot of Relistor and I've been backed up for over a month . I could feel it helping out but it takes some time so I gave it 24 hours and then I went to get a colon irrigation and let me tell you it was almost painless. I say it works. No adverse effects and I finally felt like things were working again because before it felt like everything was closing down whenever I tried to poop. I feel like a new man . Get some help guys try an enema after a while if relistor doesn't work. Watering the dry stool will make it almost painless. Goodluck:)"

10 / 10

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8 Report

Leila
Taken for less than 1 month
July 16, 2021

"I've just started taking this medication so I can't say about the longevity, whether it'll always work the same, etc. BUT so far it works great. I take 3 of the 150 mg tablets and in about 2 hours I have a bowel movement. I've been on morphine and dilaudid for about 12 years and I've always had issues with painful constipation. The OTC laxatives usually cause so much pain I'd avoid them, only using miralax every now and then. I really like the relistor because the stomach cramps are minimal compared to laxatives. The poops were still kind of hard but maybe I just have to get the hard ones out before they start forming softer. I wish more came out but maybe if I take it longer it will get better."

8 / 10

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6 Report

Funsi...
Taken for less than 1 month
February 6, 2021

"So I was injured in car wreck in 2018, herniated a couple of disks in my back and I also have an issue where my disks are disintegrating. So after the wreck I was on pain pills for about 9 months talked to my dr because I was scared of being physically dependent on them. Dr put me on belbuca started low now up to 750 twice daily. Never had any issues going to the bathroom until all the pain meds. Dr gave me a few samples of relistor yesterday, took my first dose this morning nothing yet, I hope it works eventually....Was hoping for the 30 minute miracle lol.."

1 / 10

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5 Report

Bob
Taken for less than 1 month
July 24, 2019

"I have been experiencing OIC and have been using every otc and natural remedy available. The issue has been ongoing for several months. I took my first Relistor injection 5 hours ago without success.I added some suppositories, magnesium citrate and a fleet enigma and expelled some gas and a few pellets of poop. Why have I not experienced and What can I expect with another injection tomorrow? This problem is totally incapacitating."

1 / 10

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5 Report

LarryDC
April 27, 2017

"Worked fine at first and then after about 6 months when I took the shot, it would take 2 hours for any thing to happen."

8 / 10

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25 Report

Curdc...
Taken for less than 1 month
May 17, 2017

"Been on the tablets for a week and only went one time and it was difficult to pass. Not happy"

1 / 10

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22 Report

Dennis
April 19, 2024

"It's been a big help. It generally takes a few hours to work but is effective almost every day."

10 / 10

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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.