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User Reviews for medroxyprogesterone systemic

Also known as: Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about medroxyprogesterone systemic.

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Amenorrhea 5 review(s) 28 medications
9.6
Endometriosis 6 review(s) 153 medications
7.6
Abnormal Uterine Bleeding 12 review(s) 151 medications
7.1
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6.1
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Sort by: Reviews for medroxyprogesterone systemic

MemberTinaR. said:
User Rating:  
7.0
Depo-Provera (medroxyprogesterone) for Birth Control: I've been on the shot for about 9 years on and off. What I mean by on and off is that I take about 3 shots instead of 4 shots a year. I started doing this because after the 1st year of being on the shot I found out I had precancerous cells in my cervix. Not positive that the shot caused this but I give my body a break for several months before I start again. Every time I start the cycle again I get a different side-effects. I usually have a very high sex drive during the 1st month and 1/2, I always have acne, always have mood swings and depression, sometimes I get headaches, and I gain weight continuously regardless of diet and exercise.

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November 19, 2009 9:37 PM
MemberBeyond the Pink Ribbon said:
User Rating:  
9.0
Depo-Provera (medroxyprogesterone) for Endometriosis: I've been on the Depo-Provera injection since the 1994 inception of off-label use for Endometriosis. For the last few years I've started having some side effects over the two - four weeks prior to each injection including severe fatigue and hot flashes. I'll take those side effects any day compared to how I lived when my "Endo" ruled my day to day life. I've been pain free for years as a result of the 15 years of Depo injections. Other side effects? I guess we will see.

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November 7, 2009 1:15 PM
CAIT (unregistered) said:
User Rating:  
4.0
Depo-Provera (medroxyprogesterone) for Birth Control: WELL I'VE BEEN ON DEPO FOR ALMOST 8 YEARS NOW, AND THE ONLY BENEFIT IS I HAVE NO "THAT TIME OF THE MONTH" BUT I'VE HAD MAJOR WEIGHT GAIN, NO SEX DRIVE, AND I BREAK OUT MORE THEN I HAVE WHEN I WAS IN HIGH SCHOOL! IT'S A GOOD BIRTH CONTROL, BUT THIS LAST SHOT I HAD IS MY LAST. NOT GOOD FOR MY HEALTH, YOU WOULD HAVE TO TRY IT YOURSELF AND SEE IF ANYTHING HAPPENS TO YOU. I SUGGEST WATCH IT CLOSELY.

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November 3, 2009 12:08 PM
Memberpb2 said:
User Rating:  
8.0
Depo-Provera (medroxyprogesterone) for Birth Control: Been on the shot for 6yrs Doctor told me I've been on it to long so I didn't get my last shot in July, still waiting for my period and they don't know what to tell me when I ask how long. Never had acne before, now I do and definitely gained weight. As a birth control I love it. Never had a period and don't remember to have to take daily pill.

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October 30, 2009 9:57 PM
kmcmumof3 (unregistered) said:
User Rating:  
5.0
Depo-Provera (medroxyprogesterone) for Birth Control: I am 29 years old and I have had 3 jabs of the depo in the last year and a bit, MY PRO'S: No period pain every month. No babies ( three is enough for us ). No worries about tampons etc. My CONS: headaches alot, Mood swings - am a little depressed and snappy at the kids, I don't want to get intimate with my poor husband at all, and my face is covered in acne (not really, but for me YES). I have gained weight!! (5kg) I was supposed to have my next jab in June this year and I didn't go for it and I still don't have my period 5 months later!!! I think for me personally, It is no good.

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October 29, 2009 7:45 PM
Anonymous user said:
User Rating:  
4.0
Depo-Provera (medroxyprogesterone) for Birth Control: Depo Provera was the first hormone birth control I used. I only got it once. Pros: no pregnancy; no weight gain; no period; didn't have to worry about taking a pill everyday. Cons: was in tears for basically 3 months straight; sharp decline in sex drive; increased acne (probably from crying all the time); bleeding for 4 weeks straight when I got off it.

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October 28, 2009 4:07 PM
undecided (unregistered) said:
User Rating:  
8.0
Depo-Provera (medroxyprogesterone) for Birth Control: I have been getting the shot for a little over a year now. At first I loved it. I never got a period, no mood swings, a little weight loss, it was amazing. The only thing I am considering switching for is that I got really bad acne. I asked the nurse that gives me the shot if that was from the shot and she said no it does not cause acne, but I never had acne like this before. Other then that it was great.

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October 5, 2009 8:11 PM
MemberAngelicurse said:
User Rating:  
5.0
Depo-Provera (medroxyprogesterone) for Endometriosis: I have taken Depo-Provera now for 4 years. It took care of the severe pain, cramping, and hot flashes. I have also not had a period since or even spotted. Although it has helped positively with these things there are negative side effects. I gain and plateaued at a whopping 57 pounds. I gained the first 25 pounds in the first 3 months, keeping in mind that I had not changed eating habits or exercise, and now I have stretch marks from the rapid weight gain. All I can say is to try it yourself, this is just how it affected me.

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September 26, 2009 10:40 PM
Anonymous user said:
User Rating:  
1.0
Depo-Provera (medroxyprogesterone) for Birth Control: I became pregnant with twins, as I was not informed to refrain from sexual activity for 2 weeks.

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September 26, 2009 12:00 AM
Anonymous user said:
User Rating:  
3.0
Depo-Provera (medroxyprogesterone) for Birth Control: Been on the Depo for 3 1/2 years now. No periods. Terrible weight gain. Mood changes. I'm looking to get off of it.

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September 23, 2009 8:42 PM
Anonymous user said:
User Rating:  
8.0
Depo-Provera (medroxyprogesterone) for Birth Control: I was on the Depo for about 2 1/2 years, and after some initial spotting (about 9 months) I loved it. Super easy, nearly painless, very effective. If it weren't for the bone loss controversy, I'd still be on it. I didn't notice any side effects, my period was replaced by light spotting about 3 weeks before I was due for my next shot.

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September 15, 2009 2:04 AM
Anonymous user said:
User Rating:  
7.0
Depo-Provera (medroxyprogesterone) for Endometriosis: I had been on Depo for 5 years as a birth control method. I knew that there was always something wrong with doctors. They just told me that I had bad period cramping and basically to deal with it. It is only now after I stopped the Depo, to try and fall pregnant, that doctors have now tested me for and confirmed that I have endometriosis. The pain that I am in now is crazy, but I am not going to go back on it in the hope that I may just by chance perhaps fall pregnant! It worked really well for me when I was on it though, had no cramping as my periods had stopped completely.

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September 14, 2009 10:39 PM
rissriss (unregistered) said:
User Rating:  
10
Provera (medroxyprogesterone) for Amenorrhea: Stopped getting my period so I took this and it worked right away. It didn't bring back my monthly cycle but it brought on a cycle after the last pill.

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August 28, 2009 12:32 AM
Anonymous user said:
User Rating:  
9.0
Depo-Provera (medroxyprogesterone) for Endometriosis: Depo has been great for relief of pain from endometriosis. I am on my 3rd shot. No more period, but I do spot the whole month before the next shot is due. I am hoping that will stop as my body gets used to it more. The shot is painless, the only side effect I have noticed is minor weight gain and my sex drive has decreased a bit. I am okay with that at least the pain is gone. I got scared reading what everyone had to say about this drug and almost didn't get it. I am glad I took the chance to see how "I" reacted to it. Everyone is different. I am very satisfied with it.

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August 27, 2009 12:55 AM
FRUSTRATIVE (unregistered) said:
User Rating:  not submitted
medroxyprogesterone for Abnormal Uterine Bleeding: It helps to regulate my menstrual cycle that lasts approximately 1 to 2 months straight, with huge blood clots.

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August 26, 2009 3:25 PM
Member351 said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Birth Control: I love it

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August 19, 2009 11:00 PM
Membercmtimm said:
User Rating:  
1.0
Depo-Provera (medroxyprogesterone) for Birth Control: I had been using Depo for about 3 years. I spotted for almost a year and then my period went away all together. I had a 5lb weight gain, which isn't so bad. I had a decreased libido. But I think worst of all was that I had terrible acne. I've never had acne like this. I've been off the shot now for 8 months and I just got my period back (though irregular) about 2 months ago. My acne is still there but seems to be getting a little better. As a birth control, it was easy and it worked.

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August 10, 2009 11:24 AM
Anonymous user said:
User Rating:  
1.0
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I have been bleeding for six months now! I was on the Depo for three years then, I went off of it. I am 35lb heavier and my eating habits and work outs never changed. I felt horrible all the time, headaches, back pain. As birth control it sure works great.

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July 30, 2009 8:52 PM
Select Members have provided additional information by completing the member surveytammccoy said:
User Rating:  
9.0
medroxyprogesterone for Birth Control: I have been using this since the birth of my second child 14 and 1/2 years ago. I love it. No periods. No daily medicines to try to remember. I have had a bone density scan and it was normal so worries there either. I think it is great!

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July 29, 2009 7:10 PM
Anonymous user said:
User Rating:  
5.0
Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: Multiple cervical polyps: I have been taking this medication for 3 months, for 14 days each month. Side effects include increased hunger (actually I am pleased about this as I am rarely hungry and don't really enjoy food). I have read that it can cause depression, but for me it is the opposite. I am far less depressed and have more energy and feel less overwhelmed. The effects only last for the 2 weeks that I am taking it each month. My body seems to love this medicine. It is too soon to ascertain whether my polyps have shrunk/disappeared. I am going to be re-tested in three months. If it hasn't worked then I am going to try the Mirena coil.

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July 1, 2009 5:35 AM
Anonymous user said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Birth Control: I have been on Depo-Provera for 11 or 12 years and love it. I started out with very few periods and all of them were very light. Now I normally will lightly spot or clot before my next shot is due. Now I never have any periods so it's been great. The only problem I've had is just recently, for my last shot I went to a different doctor and they gave me the generic version which caused me to bleed very heavily and severe cramping so I know to never use the generic form again.

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July 1, 2009 12:24 AM
Membersaugustsays said:
User Rating:  
3.0
Depo-Provera (medroxyprogesterone) for Birth Control: It started off great, for the first month. But then by the second month, my period became a monster. It lasted for so long and started on a very random day that wasn't even close to my regular period cycle date. Also, I'm on an emotional roller coaster ride and almost constantly angry at something or someone. I don't like this at all.

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June 8, 2009 4:31 AM
Anonymous user said:
User Rating:  
5.0
Depo-Provera Contraceptive (medroxyprogesterone) for Birth Control: Depo is a great contraceptive but side effects included weight gain for me, irritability, moodiness and loss in sex drive.

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June 4, 2009 4:02 AM
Anonymous user said:
User Rating:  
3.0
Depo-Provera (medroxyprogesterone) for Birth Control: I tried Depo for almost a year before finally switching to the pill due to repeated irregular bleeding. And the symptoms I experienced were incredibly heavy and painful like I've never experienced. It worked great as birth control though and I didn't ever get pregnant but there was no prediction or pattern to my irregular bleeding and the pain of the cramps was something I've never experienced since.

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May 28, 2009 3:14 AM
FormerDepo (unregistered) said:
User Rating:  
4.0
Depo-Provera (medroxyprogesterone) for Birth Control: After 2 years on Depo-Provera I decided to stop because I was concerned about not having my periods. My period didn't come back to normal until after 7 months, during this time off Depo I realized that suddenly my mood had improved and I wasn't sad all the time anymore. I switched to Alesse and now realize how bad Depo was for me. It made me moody all the time.

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May 9, 2009 6:53 PM
tzigane88 (unregistered) said:
User Rating:  
8.0
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I first started Depo-Provera due to irregular and heavy menstruation. The first month was the worst, with several side effects that did go away after the second shot. I had severe breast tenderness, with some lymph node swelling, mood swings, and constant spotting for the first month. After the inital shot, I never had a period again, barely any spotting, and felt well. I did go off the shot for a while and now I am on it again. I am having no side effects except for the initial moodiness and decrease interest in sex. But I would still recommend this product for someone! No periods - Sign me up.

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May 3, 2009 10:36 AM
Anonymous user said:
User Rating:  
10
medroxyprogesterone for Endometriosis: I have used Provera for four years and have never suffered from any side effects. The only draw back is that my doctor insists that I have a period every 3 months. I take 10mg 3 times a day and this stops my periods and therefore all the problems that are associated with endometriosis. I only wish I could take the pills permanently.

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April 20, 2009 2:50 PM
Anonymous user said:
User Rating:  
3.0
Depo-Provera (medroxyprogesterone) for Birth Control: I had nothing but negative effects from the Depo shot that are continuing even after the duration of action of the Depo. I am now experiencing terrible migraines (I rarely, if ever had even minor headaches). They have been occurring multiple times per day including nausea and diarrhea. I experienced these same symptoms for the first time after I received my first shot. I also experienced neck stiffness, severe mood swings, bouts of depression that seemed to arrive from nowhere, no sex drive what so ever, and worst of all menstrual bleeding for an entire month straight which was only counteracted by a high dosage of birth control pills.

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April 12, 2009 12:33 AM
ashgoldman601 (unregistered) said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Birth Control: I am 17 and have been on the shot for a year now. I already have 2 kids and this form of birth control seems to be very effective. I can't remember to take the pill so the shot is great for me. The only problem I have with it is I can't seem to lose the pregnancy weight from my second child. But I rate it a 10!

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March 29, 2009 2:41 PM
SassyKay (unregistered) said:
User Rating:  
8.0
Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I am 47 and this is my second time on Provera. The only side effects I have noticed are intense night sweats. I am hotter than usual. The day after my first dose, I was nauseous and had a headache like a hangover, it has happened a few other times during the 10 days. I do think, that I can live with 10 days a month of the Provera because I was bleeding a lot. I was stuck at home. At least now, even if I don't feel good I can still leave home.

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March 25, 2009 4:54 AM
Anonymous user said:
User Rating:  
1.0
Depo-Provera (medroxyprogesterone) : I have been on Depo for 18 years and until just recently would have rated it a 10. I have never had a period or any other complications that I knew about. I have always taken calcium along with a multivitamin. Why the 1? Because while sick with bronchitis I fractured 2 ribs, coughing and I am only 32. Come to find out, my doctor has attributed it to the Depo. My advise, make sure to talk to your doctor about a bone density test.

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March 19, 2009 3:54 AM
MemberJane F said:
User Rating:  
6.0
Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I am a 51 year old female. In January 2008 I had a light period that lasted for 4 days and then stopped. Five days later I started bleeding again. I had such a heavy flow with clotting that I had to change every 2 hours. After the 14th day, I began to get very weak. My mother convinced me that this was not normal and to see a gynecologist. On day 16 of this heavy bleeding I went to the gynecologist. She told me I was going through menopause and prescribed Provera. On the next day, I was to take 20mg for 10 days. After 2 days, I stopped bleeding. On day 12 my doctor told me I needed to do this for the next 3 months and each month would get better and it would help me through menopause. I do not feel good at all when I take the Provera.

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March 14, 2009 11:13 AM
Anonymous user said:
User Rating:  
3.0
Depo-Provera (medroxyprogesterone) for Endometriosis: I had extreme nausea and vomiting within a week of getting my first and ONLY shot of Depo-Provera.

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March 5, 2009 5:01 PM
No depo for me (unregistered) said:
User Rating:  
1.0
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I was on Depo for about 6 months and started having a period for months on end. I'm also a kidney failure patient so that doesn't help things. But everyone I talk to says they have a period for a long time.

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February 21, 2009 8:30 AM
Amy in Vegas (unregistered) said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Birth Control: I have used Depo-Provera since I was 16. It started to control my period as it was irregular, and ended up years later as birth control. I have never had a period since my first injection, also never had any side effects. This is an awesome idea for someone who is irregular or just hates that time of the month. The only bad side to this medicine is I have lost a lot of bone density in the 8 years I have used it. My advice is take lots of calcium while using this drug. Other then that it's great and I have recommended it to others in my years of using it and will continue to.

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February 6, 2009 1:00 AM
D. Marie (unregistered) said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: Using the product has really improved my quality of life. I can once again be the active person I meant to be without the constant worry and inconvenience.

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January 20, 2009 1:38 PM
Anonymous user said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) : I was on Depo Provera for almost 3 years, after I had my daughter and didn't have a period the entire time. I've been off for a year now and still didn't see my cycle. I want two more kids so I told my doctor and she prescribed me medroxyprogesterone. It took a month (almost two months) to get my cycle but I finally saw it and it has been on ever since. Now I'm interested in Clomid so I can get pregnant.

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January 13, 2009 8:15 PM
max618 (unregistered) said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I have used Depo for years for Birth Control and to help with other uterine issues (heavy bleeding, etc). I have never had side effects and it's wonderful..no periods! Talk about convenient. I'll never switch.

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January 11, 2009 11:15 PM
Anonymous user said:
User Rating:  
10
Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I have not had a period from the first shot. I had ZERO side effects and lost 5 lbs. I think it is an amazing product.

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January 6, 2009 4:41 AM
Anonymous user said:
User Rating:  
10
Provera (medroxyprogesterone) for Amenorrhea: I took Provera about two years ago for 10 days and it worked great for me. I also had to take Clomid on day 5-9 of my cycle and got pregnant on my third cycle. They both worked amazingly. I am now going to try again hoping to have the same luck.

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December 19, 2008 12:58 AM
LamaDaLlama (unregistered) said:
User Rating:  
8.0
medroxyprogesterone for Amenorrhea: Induced a period around a couple of days after the 10th pill was taken. Caused upset stomach, but otherwise worked well.

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December 18, 2008 9:26 PM
Anonymous user said:
User Rating:  
10
I really loved it, but after using it for 3 years I started bleeding alot. My gynocologist said that I needed to take a break for about a year. Although I love Depo Provera, I have gone back to pills to have a period on a regular basis. If you use it, you should take a break every couple years or so, but otherwise, I loved it.

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December 17, 2008 3:49 PM
Anonymous user said:
User Rating:  
10
Provera (medroxyprogesterone) for Amenorrhea: I took Provera for 10 days as per doctor's order to induce a period. On the 11th day I had a period. The medication works alright. I didn't experience any side effects.

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November 26, 2008 1:25 AM
Anonymous user said:
User Rating:  
8.0
medroxyprogesterone for Abnormal Uterine Bleeding: I am taking this medicine so my period can come. It's the second month I am taking it. It worked just fine in the first time.

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November 16, 2008 7:38 PM
hanna1984 (unregistered) said:
User Rating:  
10
Provera (medroxyprogesterone) for Amenorrhea: Medication works by inducing a period. After taking this medicine I had to take clomid and I conceived on my 4th round of medication. It works. Be patient and good things will come. I am now trying again to conceive and yes I am taking provera again and I just started my 1st round of clomid.

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October 22, 2008 4:02 PM
Anonymous user said:
User Rating:  
10
Depo-Provera Contraceptive (medroxyprogesterone) for Birth Control: Best birth control I have ever had.

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July 3, 2008 3:23 PM
aries81us (unregistered) said:
User Rating:  
10
Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: I had abnormal uterine bleeding and I didn't know why. I started passing clots & was bleeding irregularly. I thought, at first, that I was having a miscarriage. I went to my GYN. She prescribed Provera 10mg once a day for 10 days. I just finished my prescription & the only problem that I'm having now is sensitive breast. Other than that, my bleeding has completely stopped.

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March 8, 2008 11:36 PM

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