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Letrozole User Reviews & Ratings (Page 5)

Brand names: Femara

Letrozole has an average rating of 6.5 out of 10 from a total of 354 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Letrozole

  • Anonymous
  • November 18, 2011

Femara (letrozole) for Breast Cancer, Adjuvant "After reading of so many negative side effects of Femara I was hesitant to start. Since it decreases my chances of recurrence by 25% I felt I must try it. I've been on it for 1 year now and have had very few if any negative side effects. My hair regrowth has been spotty and slow, whether due to the Femara or just the general effects of chemo and radiation I'm not sure. I switched 2 months ago to the generic formula, have noticed no changes. I feel very fortunate not to have suffered many of the effects other women have reported."

10 / 10
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  • Julie
  • January 20, 2020

For Female Infertility "I have done 4 cycles of Femara 5mg from day 2 to 6 with no luck, even though I ovulated on my day 15. My Dr. has increased the dose to 7.5mg a day, hoping for the ultrasound to show number and size of follicles. Please wish me luck, been trying for 5 months to get pregnant."

10 / 10
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  • amari
  • Taken for 1 to 2 years
  • November 29, 2023

For Female Infertility "I got pregnant with letrozole after 1 year and a half of trying to conceive. My 1st OB prescribed me with clomid, and I took it for 3 months, but it did not work. My 2nd OB prescribed me with letrozole, but I had no luck for 3 consecutive months. The 2nd OB then gave me clomid for 2 consecutive months, but still no luck. The 3rd OB gave me clomid for 1 cycle and gave me trigger shots, but still no luck. For the next cycle, we tried again with no medicine intake and experienced a chemical pregnancy. I then transferred to a 4th OB, and they prescribed me with letrozole again with 1 hucog trigger shot for the 1st try of IUI, but still no luck. The 5th OB gave me another cycle of letrozole before the IUI procedure, but still no luck. The next cycle came, and I was still prescribed letrozole, but this time we returned to timing method. I am now 20 weeks pregnant!!! God bless all women praying for a baby. We can do this!!"

10 / 10
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Frequently asked questions

  • Laika
  • Taken for 10 years or more
  • May 26, 2019

For Breast Cancer, Adjuvant "Diagnosed 22 years ago with invasive lobular breast cancer, and 45 out of 48 lymph nodes contained cancer. (Really.) But after mastectomy, chemo, radiation, more chemo, 5 years of tamoxifen, a complete hysterectomy, a couple of years of anastrozole and exemestane ... I've been on letrozole for well over 10 years. I have experienced most of the usual side effects, but I've lived to complain about them. :-) No recurrence so far, although I did develop another breast cancer and had a second mastectomy 10 years ago. Overall, I eat healthy and work out, I do have energy, not much pain anymore, and I still work FT at age 66. Clearly I've been lucky. No one expected me to live (least of all me). But statistics do not determine what will happen to the individual. Life is good!"

10 / 10
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  • Anonymous
  • December 13, 2009

Femara (letrozole) for Breast Cancer "I am 52 years old and I too feel older than I am. I already have problems getting out of bed and I suffered with Sarcoidosis which affect the organs and causes joint pain, sending me constantly to different Specialists. Now I am taking Femara and it's not only causing me more pain, but it's causing my hair to fall out or thinning! I also notice that my vision is impaired sometimes when I'm driving and I only drive when I have too, but sometimes I find myself trying hard to focus. This is scary! I am calling my Oncologist tomorrow morning first thing. "

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Are you taking this medicine?

  • minne...
  • September 12, 2015

Femara (letrozole) for Breast Cancer "Hi everyone, in 2011 I was diagnosed with stage 3A invasive ductal breast cancer - I went through chemo for 4 months and had double mastectomy in March 2012 - followed by 6 weeks of radiation. I was put on tamoxifen for a year and then femara which I currently take now. The biggest thing with femara is being like I am constantly tired and "foggy" - I can handle the hot flashes ( we live in Minnesota - where the winter lasts for 6 months) - I just walk around outside with a t shirt on and I'm good to go! Lately, I have been experiencing hair loss and I don't know if its due to the femara? Anyone else have this problem? Please let me know. Hang in there beautiful ladies (& men)"

7 / 10
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  • april
  • March 21, 2016

Femara (letrozole) for Breast Cancer "I have been on this drug for about 3.5 months now. I was on Aromasin (exemestane) for 2/5 years prior to starting letrozole. I was so hopeful that some of the horrible side effects would not affect me like they did on the exemestane...and for a while, it was not too bad. Now, in month 3, the side effects of severe joint pain, brain fog and shortness of breath are back with a vengeance and the last 3 times my blood pressure was taken, it was inching back up even though I started BP meds after the exemestane raised my BP. I never had any issues with my BP prior to taking these aromatase inhibitors. I guess my PCP will have to raise my dose of BP meds. I am also peeing constantly on letrozole and my hair is coming out more on my brush! UGH!"

2 / 10
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More FAQ

  • Sheila...
  • Taken for 2 to 5 years
  • September 13, 2019

For Breast Cancer, Metastatic "I was diagnosed with Metastatic breast cancer 2-9-2016. I am ER and PR Positive Her2 Negative, I am still on my first line of treatment (Letrozole 2.5 daily.(Bone Metastasis only!) Zometa infusions every three months Letrozole has been a wonderful drug for me. Very Minimal side effects. I am currently in month 43 of Letrozole (Femara). I am very thankful for the makers of this drug..."

10 / 10
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  • Hails
  • Taken for less than 1 month
  • November 23, 2019

For Breast Cancer "I didn't take this medicine, but my grandma did. I lived with her and have seen how this medicine affected her. She started letrozole on a Friday and by Thursday she was in ICU. Before she was hospitalized, this medicine caused her extreme discomfort. She was in bed all day every day. She has fatigue, weakness(so bad she couldn't sit up by herself), hot flashes, throwing up, joint and muscle pain, fever and dizziness. Thursday she got so bad to the point she was struggling to breathe. In the hospital they discovered a blood clot, which is a side effect. 2 weeks before she started this medicine she went to the dr and had a MRI and a CAT scan. There was no clots. This medicine made her miserable. Now she is in ICU, and we was told she probably will not be coming home. She was fine until she started this medication."

1 / 10
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  • deepa...
  • Taken for 2 to 5 years
  • October 21, 2020

For Female Infertility "I took letrozole 2.5 mg last month and one egg got matured as well but did not conceive. This time doctor increased dose from 2.5 mg to 5 mg and given the shots as well. I am 11 DPO and hoping for the best. Baby dust to all of you"

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  • Cassy
  • Taken for 6 months to 1 year
  • February 27, 2020

For Female Infertility "Hi All. I would like to share my experience. I've been in TTC since July 2019 and tried letrozole for a couple of months now. Got my period at November 20, December 20 and January 20. However, as of this time I still don't have period yet. Base on my period tracker I ovulated at February 9. Technically, more or less i'm now 18dpo. I took a pregnancy test multiple times but still negative. I will visit my OB this coming Saturday to check why my period is late."

8 / 10
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  • Caner...
  • Taken for 1 to 6 months
  • August 18, 2015

Femara (letrozole) for Breast Cancer "diagnosed May 2014 with Stage 3 Breast cancer after chemo, removal of the tumor & lymph nods, radiation I started Femara been on it almost 6 months and I have daily joint & muscle pain, fatigue, hot flashes, and most of all weight gain, Im really trying to eat healthy and exercise, but working a full time job its a tough routine to keep up with everyday, (55 and post menopausal). But hey Im still here and hopeful the medication does the good job of keeping the cancer at bay. Doing my best with the symptoms."

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  • too...
  • November 11, 2015

For Breast Cancer "The pain to my shoulder and right arm are so intance that I can not function. I have problems taking care of my chores to the point that I just can not do them. My arm has become immovable due to stiffness and the profound pain. I can't sleep at night unless I double on a sleeping aid. I can't live this way. My life is depressing."

1 / 10
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  • Cryst...
  • Taken for 1 to 2 years
  • September 21, 2015

Femara (letrozole) for Breast Cancer "I have been taking Letrozole for one year now after a diagnosis of hormone related breast cancer. Initially my consultant (UK) said I would need a right sided mastectomy. However two weeks later when the biopsy results were back he said he did not think surgery was possible because the tumour appeared to be attached to the muscle. However, CT scan and MRI revealed a 1mm plane between the tumour and the muscle - phew! Letrozole was so effective that it shrank and softened the tumour and by January 2015 I was able to have a bilateral mastectomy. Lymph glands and bone scan were clear. Side effects: persistent hot flashes, so I always wear blouses with buttons and carry an ordinary fan in my handbag; it is a life saver."

8 / 10
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  • TTCJo...
  • Taken for 1 to 6 months
  • November 14, 2021

For Female Infertility "I wanted to post on here to share my story and give women who are currently TTC hope, as I was in their shoes not only a few days ago. My partner and I had been trying to conceive for over a year and due to my PCOS condition we knew it would be more difficult. We followed all our doctors orders, first we went to a GP who then referred us to a fertility specialist who prescribed me with 2.5mg of Letrozole taken cycle day 2-6. The first cycle I ovulated (confirmed with blood test) but no pregnancy. 2nd cycle I kept track of my BBT and cervical mucus. I only noticed one day where my CM was egg white and stretchy. I recorded everything on Fertility friend app. I started testing from 7DPO. One each day- sometimes two cause I have no self control. Finally my first BFP arrived at CD15. Please don’t lose hope. It does work. May this story inspire you to hang in there and keep at it."

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  • Cavam...
  • March 30, 2015

For Breast Cancer "I'm not sure how to rate this drug. If it keeps cancer away, it might get a 10. Almost 4 years later, it appears to have done so. However, the jury is still out. I am literally counting the days until I can get off this drug. The joint pain has become almost unbearable and completely affects any quality of life. I find I don't want to do much of anything because of the pain, yet know I have to or be almost bedridden. It has become progressively worse in the last year. So I push myself daily and have tried almost everything to help the pain, but nothing really works. I am grateful to be cancer free, and really feel conflicted even complaining about it. But most days are just very hard. I am 63, yet feel like a 90 year old."

5 / 10
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  • Sexy...
  • Taken for less than 1 month
  • February 25, 2020

For Breast Cancer "I have been using this drug letrozol for almost a month.. I have chills so bad I can't warm up. Headaches can't sleep and have diarrhea and dizziness.. I am also have muscle spasms and pain in my bones. Help"

1 / 10
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  • H For...
  • Taken for 1 to 2 years
  • September 27, 2016

For Breast Cancer "I've been on letrozole for a year. After doing preliminary research about it, I really didn't want to go on it, but felt I had to give it a try. The most serious SEs for me were severe joint pain and feeling frail; mood swings, and strong hot flashes. The first 2 were bad enough that, after being on the drug for 8 months, I decided to take a break from it. I went off for 3 weeks, then started back, but now I take it at night before bed. I also started walking to keep weight gain at bay. Since making those 2 changes, I've had no more joint pain or mood swings, and I feel healthier than I have in a long time. Still have hot flashes, but they're tolerable. I'm not sure why those changes would make that much difference, but they do."

8 / 10
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  • MVR
  • March 3, 2012

Femara (letrozole) for Breast Cancer, Metastatic "After a year on Femara I am beginning to experience severe hair loss, bald patches on top of my head and the hair is turning thin and brittle. Insomnia for the last 2 months, pain in my joints, I was diagnosed with Glaucoma and am very forgetful, i.e. find it defficult to concentrate. But, if Femara stops the recurrence of cancer, I'll keep taking it. If it just were not for the hair loss. "

5 / 10
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  • Bus...
  • Taken for 5 to 10 years
  • February 26, 2020

Femara (letrozole) for Breast Cancer "Caused me weight gain, serious hot flashes, did not have joint pain, headaches, or dizziness before starting this medication. I know these are listed possible side-effects, however, these do cause some functionality issues."

7 / 10
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  • Sarah...
  • January 25, 2017

For Breast Cancer "Yesterday I completed five year on Letrozole! Over the past two years I have had awful joint pain in my knees, outers thighs and wrists. My body aches all over and I feel exhausted every day. I wake in the morning with stiff hands and fingers. My oncologist has now taken me off letrozole as I have completed my five years and told me that my aching body and joints should gradually get better."

5 / 10
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  • Bren
  • Taken for 1 to 2 years
  • May 2, 2018

For Breast Cancer "I had a mastectomy after finding a small lump (with prd caber cells) in breast tissue. No rounds of chemo needed. Lymph nodes clear. I have been on Letrozole and Anastrozole for a year and a half. Both gave me pain in my joints and muscles. Mostly in my hip, legs and hand. I couldn’t walk far as my legs were weak. Made me tired. I decided to stop them altogether. They were making me disabled and unable to do my job properly. I felt eventually I would be in a wheelchair and unemployed. My consultant looked at a graph and said because I was a low risk of cancer returning I decided to stop taking them. I told him I prefer quality of life over quantity. I’m now hoping I get back to normal. It’s been a week now and already the pain on waking is better."

2 / 10
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  • Rocky...
  • Taken for 2 to 5 years
  • January 23, 2016

For Breast Cancer "Dec 2011 bilateral mastectomy stage 1 infiltrating lobular breast cancer rt breast 64 yrs old - no lymph node involvement I am in my 4th year of hormonal treatment with Letrozole. So far so good some joint and muscle pain but it could be my age. I exercise more - take more vitamins - eat more vegetables - shun all dairy products (cows are always pregnant and full of cow hormones) - eat very little meat (chicken or fish) - always shop organic - and get at least 7 hrs of sleep a night. Some people think I am crazy."

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  • flginny
  • January 9, 2016

For Breast Cancer "I would give a lot to have NEVER taken Femara! It aged me 20 years in a few months. I took it for more than six years before I told my oncologist I would not take it any more. It was killing me! I was sleeping an average of two hours a night......a "good" night was five hours every ten to fourteen days. The other side effects were awful! Femara did NOT keep the cancer from coming back! It is KNOWN to weaken the bones, and the cancer is now rampant in my bones!"

1 / 10
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  • cmmomof
  • August 6, 2015

For Breast Cancer "I have stage 4 breast cancer and the looks at the hospital were not pretty-it did not look good for me. I have been on Letrozole for 6 months and it is working. The tumors are shrinking or disappearing and I feel so much better. My hands feet and legs are stiff but so what- I stretch them to loosen up, my hair is thinning but so what, there are other things I can use to cover my head. If God put this drug to cure me, I can take these small inconveniences. I am happy to know that this joint pain is caused by the medication. I would like to know if the medication actually heals and makes you cancer free and it can end or if medication is needed for my life. I am 54 almost 55 and if this pill can give me life, small side effects are ok"

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.