Glimepiride for Diabetes, Type 2 User Reviews (Page 2)

• Ginny
• Taken for 1 to 6 months
• August 24, 2019

"I was taking Januvia and Invokana but it wasn't quite enough so my doctor added glimepiride. I started taking it 3 months ago and it really worked! My A1C dropped to 6.7 and I average 120-130 blood sugar. My blood sugar bottomed out a few times since starting it but I just have to plan snacks and eat properly. My only complaint is I gained weight since starting it and I'm hungry more often."

• MaryMJ
• Taken for 1 to 6 months
• April 20, 2016

"I have been on this medicine for about a month and do not like it at all. My new insurance does not cover kombiglyze so this was what my Dr. chose. I eat breakfast and take this medication. Not more than two hours later I am getting hungry, I start getting anxious and cranky and start shaking. My blood sugar reading will be in the 70 but I have to eat right then or I will get a splitting headache. It takes me about an hour and a half at least to get my blood levels back up but for the rest of the day I feel lethargic and almost like I'm half drunk. I have to get off this medication, I feel like my emotions are on a roller coaster! I don't have time for this!!"

• LeeC
• Taken for less than 1 month
• March 11, 2013

"Been on insulin almost 3 years and metformin. Stopping insulin and taking 4 MG glimepiride 2x daily with breakfast and dinner. Doctor did because A1C was too good 6.2. Only reaction after 6 days is having sweats constantly (but sugar is not low). I cannot see this on any reactions. I am having mild insomnia too."

• Roami...
• April 15, 2011

"After 10 years on metformin XR, my blood sugars began to creep up. My A1c was now in the mid-7's. Doctor kept me on my 4 tabs of 500 mg each of metformin XR - which I take four times per day, about every 8 hours. He added 1-2mg tablet of glimepiride, 1/2 at breakfast, and half at dinner. The lows about 2 hours after taking the breakfast dose were immediately a problem. I then switched to a 1/4 tab (cutting that tab into 4 parts is a skill in itself), four times per day, and the lows became minimal. And my A1c is back to 6.4. I see that it is recommended to take at breakfast, but my doctor has allowed me to adjust my medications. It has been better that I control the times."

• Love...
• Taken for 1 to 6 months
• April 16, 2015

"I have been taking Glimepiride for 5 months now and it works great and if I cut the carbs/candy out my sugar is so good that sometimes I don't have to take it at all. My A1C was 8.9 and the Dr said if it goes to 10 then they will put me on insulin. I am praying that my A1C has gone down. I get tested next week. I crave candy everyday and have not stopped eating it."

• granny
• Taken for 2 to 5 years
• August 22, 2019

Amaryl (glimepiride) "Amaryl gave me horrible stomach pains. I finally had to quit taking it. I did a very strict diet, which worked until I got an infection, and had to go back on it. I had to quit again for abdominal pain. The dr put me on insulin, tresiba once a day. It worked well at night, but had to go on a sliding scale of regular during the day. I feel so much better now, and after 6 months, I am finally getting my digestive system back to normal. I have a friend on 4 different oral meds, and still struggles. I've known insulin dependent diabetics for years, my son has it for 45 years and no complications from meds or diabetes. He does follow the diet he is supposed to, and enjoys food. I say food was my enemy, until I started on insulin. I also am trying to straighten out my liver, after Amaryl caused a problem with it, too."

• Lilly
• October 23, 2019

Amaryl (glimepiride) "Two weeks ago my sugar levels were running anywhere from 500 to even getting a reading of HI on glucose meter, my doctor started me on Amaryl 2mg in morning and 2mg evening. My levels have came down to to an average of 450. I just recently started with the Ozempic shot once a week. No more decrease with numbers doing this. I am hoping it continues to come down..But my feet still burn and sting severely...Any other suggestions?"

• Panda
• Taken for 2 to 5 years
• July 31, 2019

"Been taking this for 2 years and no change at all A1C stays around 7.6, I also have been on a diet to reduce blood sugar and walk 2 miles a day. Big issues is I can't lose weight and my A1C is better when I don't take it. Did an experiment first A1C test when I have not been taking it 7.0. Second A1C test 3 months later and taking glimepride twice a day total 8mg A1C was 8.3. Told my doctor this and he said just keep taking it and we will retest in 3 months. I would love to get this under control."

• mikea...
• Taken for 1 to 2 years
• March 31, 2020

"I take two- 6.25 in the morning for the last year and am also on alogliptin 1 time a day and still can't get my blood sugars down below 160-180. I can't exercise except walking with walker because of neck surgery and bad back (three disc missing in lower back. L-1 to L- 4 is bone on bone) so the typical exercise I can't do i can't bend over. I watch my diet. (I used to weigh 300 now. I lost down to 180 ) I just can't understand I use to be on insulin when I was heavy but since I quit taking metformin and switch to alogliptin and gliapride my sugars can't get to 100 -130 anymore. Any ideas? I would have gave it a 10 if it would lower my sugars a little more. No interactions no side effects no problems at all with the other 12 medications so I have just that slight problem"

• Marsu...
• Taken for 1 to 6 months
• August 19, 2018

"I was put on Glimepiride because I could no longer afford my other medication. I was on it four months, gained ten pounds in seven days, and my A1c jumped way up. Befroe this I was reaching my next goal weight...only two pounds away...so this sudden gain was devastating. I thought, well, if my A1c improves, I will just deal with the weight issue, but it got much worse."

• Jeff...
• Taken for 1 to 6 months
• May 6, 2015

"I discovered my A1c has crossed the line into the 6's and my Dr wanted to be proactive regarding this. I'm 59 and overweight. Not very active due to a limb amputation (Total knee replacement gone wrong). I saw immediate improvement with my blood sucrose numbers. I also started reading food labels and after reading some diet suggestions, I try to target meals below 55-60 carbs. My pre-meal numbers run from 60 to 120."

• Chatusa
• Taken for 1 to 6 months
• March 15, 2019

"I’ve had nothing but stomach pain and diarrhea as side effects from glimepiride. I didn’t take it for 2 days just to see what would happen. My tummy felt better I could finally eat. Then on the third day I took it with dinner bam up at 5 a.m to the bathroom. I was given two new pills at the same time so it’s got to be one of them causing this. Amaryl (glimerpiride) I believe is what’s doing it. My sugar levels are great taking only 1/2 mg daily. But the side effects are just not working for me"

• Honey
• Taken for less than 1 month
• November 11, 2018

"I just started glimeperide 2mg 3 days ago so far no effects just hungry... I was on metformin 500mg at first it gave me real bad side effects diarrhea urinating all the time and losing 2lbs a day. Glimepiride seems to work better for me."

• MaryAT
• February 6, 2018

"Medication makes my sugar go low below 70 I take it in the mid afternoon because I don’t want it to do it at night. My sugar is spiking and dipping all day long. I feel like a zombie and then the next day I feel like I have a hangover! I've be been on it for 6 months and I can’t do it anymore. I want my life back!"

• Sha
• Taken for 1 to 2 years
• December 9, 2017

"After a rare side effect from Metformin, my doc put me on this. It's worked really well at getting my numbers down. I will get tummy aches if I try to take it with too little food. It can also make me munchy or my blood sugar dip an hour or two after taking. But as long as I have something on hand for it, it's not major for me. I agree with comment that a mid-morning snack is probably a good idea with this. Also, I noticed that when I eat things that are sugary, my body is better at saying "enough" and an aversion to things too sweet. That's a good addition. Overall, I can't complain. Seems to do the job with minimal interference in my life."

• kennedy
• Taken for less than 1 month
• February 17, 2017

"After two weeks on this medication I got severe stomach pains and feelings of fullness. The pains went away about three days after stopping this medication but three months later still have the fullness. Now I have to have a camera put into my stomach to see what's going on."

• Rose
• Taken for 6 months to 1 year
• July 19, 2022

"BE VERY CAREFUL WITH THIS MED! Took it for 6 months and it was working well then started having seriously low blood sugars of 50-55. Reduced the dose and it did not matter. Happened to me while on vacation walking on the beach with no phone. I had a difficult time making it back to my family. For some reason my body started reacting badly with super low sugars from it, even with a reduced dose. Scary drops from 190 to 50 in a few hours. I had to stop taking it. Dr. had no idea why it starting happening. No change in my diet or exercise. These diabetic meds are all scary except for Metformin."

• glime...
• Taken for 1 to 6 months
• September 4, 2021

"I have been on metformin and have tolerated it well. Glimepiride was added since my AIC were at 8.4, after 3 months of taking it, there was no difference. I also gained 10 pounds. This medication does give you an appetite but I didn't expect this type of weigh gain. No good for me. Unfortunately there are no other options for those without insurance. Investing which other one I can take without it being $500 per month."

• lordo...
• Taken for less than 1 month
• January 7, 2023

"I am Type 2 diabetic. I was on Metformin and during covid season my A1C went to 8.5. My doctor prescribed me glimepiride 2mg dose once a day in the morning with food. It so happened that I had BG Sensor on me that time, and I checked in night and it started dropping sugar level to 70. Next day it went to 45. I was not sure if my sensor was bad or something else was causing the problem. I stopped taking glimepiride and reading started showing me around 100-110 (fasting). Be careful with this medication unless you have a way to check daily twice a day or so, sugar level could go down dramatically and you end us having low blood sugar level, condition you did not have before which is very dangerous. What I find is if you have sensor, try different combination of diet and pills and see what works better for you. I ended up going on low-carb diet (careful on bread and rice) and I am able to manage my sugar level with one pill a day of Jardiance. Note: Jardiance did cause me UTI once."

• HEH
• Taken for 1 to 6 months
• January 22, 2022

"I was put on Glimiperide 1mg since my A1c was over 7. I take it with 2 metformin pills in the morning. My blood sugar has been 140-170 in the morning. It did not work for over 2 months then suddenly one day I was shaky after work. Blood sugar dropped to 68. It has never been near 100 or under in over 15 years. I was feeling bad eating low carb with no results at first. Now I need to check my sugars more often. I also take 2 metformin at night and Ozempic 0.5 once per week. Strange that a low dose works that well all of a sudden. But happy I do not need insulin!"

• krsyko
• Taken for 1 to 6 months
• April 21, 2024

"I have added this to my metformin regimen. I have dropped from 15 units long-acting and prandial fast-acting 5 units per meal. I am no longer on meal shots; I have dropped to 4 units long-acting. I have dropped my A1C from 10 to 6.5. Real talk, this has been good for me."

• Donna...
• June 24, 2008

Amaryl (glimepiride) "Amaryl has worked for me beautifully."

• Flippoo
• October 3, 2013

Amaryl (glimepiride) "My doctor put me on Amaryl & it quickly lowered my readings. My problem is that I have a SULFA allergy & now I'm broken out in a HORRIBLE RASH & the doc doesn't think it might be the Amaryl."

• vin1z
• November 16, 2011

Amaryl (glimepiride) "Very effective medicine, get gastric issues though as side effect. Using since 1 year."

• ladybug
• January 2, 2015

Amaryl (glimepiride) "Stomach pain and loose stools."