User Reviews for Glimepiride
Also known as: Amaryl
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Glimepiride.
Reviews for Glimepiride to treat Diabetes, Type 2
"I havae been on this drug for 6 months, still having problems maintaining sugar levels. My sugar has dropped to 44, 67,70, so I eat something before bed time. Some mornings it is at 130,160 or as high as 235. It seems as though the pill will bring levels down very quickly causing me to eat late to get them up again, only to have them rebound to high by morning."
rdh557 August 2, 2015
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"I was on Glyburide and Januvia for a long time. Then my insurance company decided that I had to take Glimepiride instead of Glyburide because it works better. I have noticed a difference already after just a few weeks. My blood sugar readings are much lower than they were on Glyburide."
blue jean queen (taken for less than 1 month) May 12, 2015
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"I discovered my A1c has crossed the line into the 6's and my Dr wanted to be proactive regarding this. I'm 59 and overweight. Not very active due to a limb amputation (Total knee replacement gone wrong). I saw immediate improvement with my blood sucrose numbers. I also started reading food labels and after reading some diet suggestions, I try to target meals below 55-60 carbs. My pre-meal numbers run from 60 to 120."
Jeff R (taken for 1 to 6 months) May 6, 2015
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"I have been taking Glimepiride for 5 months now and it works great and if I cut the carbs/candy out my sugar is so good that sometimes I don't have to take it at all. My A1C was 8.9 and the Dr said if it goes to 10 then they will put me on insulin. I am praying that my A1C has gone down. I get tested next week. I crave candy everyday and have not stopped eating it."
Love it! (taken for 1 to 6 months) April 16, 2015
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"Rather than reduce my blood sugar, this stuff actually caused a 150-200 point increase over the time that I took it. Needless to say, I'm back to glyburide for much better control."
Bunkwood Boy (taken for 1 to 6 months) March 1, 2015
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"Diabetic for 7 years. Started with Metformin only. Then added Starlix with meals. Small improvement with post-prandials. Exchanged the Starlix with glimepiride. Have been on glimepiride for 2 and a half years with meals. Does not prevent my spikes but does pull them down within a short time. The sudden drop makes me feel low when I am just "dropping" FAST into the normal range. The problem is the time it remains in effect will cause me to be low (50;s) during the night while sleeping if I take with last meal of day. Without it, I skyrocket after eating and slowly come down. My doctor is taking me off of glimepiride because of the lows while sleeping and will put me on another med. My A1C's have been climbing over the past year."
cmin (taken for 2 to 5 years) August 6, 2014
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"I've was taking Glimepiride for almost a year then a new Doctor changed me to Metformin. I see a difference between the two medications in my blood sugar level. I was doing better with the Glimepiride. My sugar levels were lower and my sugar level with Metformin are much higher. I'm going to ask to be put back on Glimepiride."
Cinful May 31, 2014
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Amaryl (glimepiride): "My doctor put me on Amaryl & it quickly lowered my readings. My problem is that I have a SULFA allergy & now I'm broken out in a HORRIBLE RASH & the doc doesn't think it might be the Amaryl."
Flippoo October 3, 2013
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Amaryl (glimepiride): "After 3 months of 2mg four times a day, with no change in glucose levels my doctor and I sat down for a talk. When asked if there was a ceiling for the dosages he said we have plenty of room to adjust (there actually is no recorded max dose I could find in the literature). The typical patient uses about 4 mg four times a day. I have found that I have had to increase as much as 16mg four times a day to see adequate glucose changes. It's ease of use and small size makes it easier to take than some, but I have yet to find it's stable dosage for ME."
Titration worker (taken for 1 to 6 months) August 16, 2013
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"After being on Janumet 50/1000 twice daily my sugar never seemed to drop at all, running very high 200 , A1c got over 12%, my GP added glimepride 4mg twice daily with meals and wow, what a difference. I've never had to worry about low blood sugar until now. My A1c after 2 months is now 7%, sugar runs around 90 in the mornings now. I couldn't be happier with this medication. Some have commented on eating right after you take this and I agree. It will drop your sugar fast, be careful. I also keep glucose tabs in my car now just in case."
Type 2_fr_Fla (taken for 1 to 6 months) August 12, 2013
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Amaryl (glimepiride): "I have been taking it for 2 years now . It will drop your blood sugar levels quickly so you need to eat within 10 minutes of taking it . If I exercise alot that will further drop my blood sugar levels . Be careful at first . I take a soda in the car with me just in case or carry glucose tablets until you see how it affects you . You may need to eat more than you are use to .I have not had any side effects"
Skullkeeper June 27, 2013
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"Been on insulin almost 3 years and metformin. Stopping insulin and taking 4 MG glimepiride 2x daily with breakfast and dinner. Doctor did because A1C was too good 6.2. Only reaction after 6 days is having sweats constantly (but sugar is not low). I cannot see this on any reactions. I am having mild insomnia too."
LeeC. (taken for less than 1 month) March 11, 2013
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Amaryl (glimepiride): "I have had the Amaryl and after 4 month my love life was gone, and another person that I know, he had the same problem. He is still using Amaryl and now even Viagra doesn't work any more."
John 2 (taken for 1 to 6 months) December 28, 2012
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Amaryl (glimepiride): "I have been taking Amaryl for 3 weeks and it has lowered my blood sugars 70 points. I do have stomach problems since taking this medication, I do find that I have to watch my sugars as after about 2 hours my sugar level drops."
cathyr46 March 25, 2012
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"After 10 years on metformin XR, my blood sugars began to creep up. My A1c was now in the mid-7's. Doctor kept me on my 4 tabs of 500 mg each of metformin XR - which I take four times per day, about every 8 hours. He added 1-2mg tablet of glimepiride, 1/2 at breakfast, and half at dinner. The lows about 2 hours after taking the breakfast dose were immediately a problem. I then switched to a 1/4 tab (cutting that tab into 4 parts is a skill in itself), four times per day, and the lows became minimal. And my A1c is back to 6.4. I see that it is recommended to take at breakfast, but my doctor has allowed me to adjust my medications. It has been better that I control the times."
Roamingrock April 15, 2011
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Amaryl (glimepiride): "This is a preliminary assessment after one month on Amaryl. I have always had an active lifestyle, but over the last two years have been disappointed not to be able to maintain an average morning blood sugar reading much below 140 since being diagnosed with Type 2 diabetes. Unlike most reviewers, I did not see an immediate reduction in blood sugar level until the last week, when my average dropped from the high 130s to five straight days between 101 and 108. This drop also corresponded to an extremely active week, tennis six straight days, bowling once and jogging a three-mile course twice. Appetite is great, so must watch weight. No adverse effects so far, even with almost daily use of Aleve as well. Will report back after longer usage."
Bob T March 28, 2011
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Amaryl (glimepiride): "Bif's comments are true. This medicine will drop your sugar levels quickly, but it works too well. Thirty minutes after taking 2mg, I can feel my sugar levels getting low. I don't have the shakes (meaning my sugar levels are in the low 60's), but I probably would in a matter of minutes. After eating breakfast, I must eat again about 2 hours later or I'll get the shakes. I must be conscious of my sugar levels for the first 4 hours after taking a dose. Overall, my fasting sugar level has dropped from 140 to 110, simply by taking 2mg each morning. However, I find I am gaining weight and overeating too."
Almost Jake March 16, 2011
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Amaryl (glimepiride): "This medication works almost too well. When you start this medicine be aware of what low blood sugar symptoms are. I have experienced several episodes of blood sugar down to 52. Heed the warning to carry glucose tablets with you at all times."
Bif May 1, 2010
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Amaryl (glimepiride): "After a year and a half of working hard at exercise and diet while taking Metformin and Actos I was not able to get my blood sugar down below 140 and it was more often between 170 and 200. I was changed to metformin and Amyril just this last weekend and after just two doses my sugars have been between 80 and 108, something I had started to lose hope could happen for me. I am so thrilled."
Anonymous September 1, 2008
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Learn more about Diabetes, Type 2
Micromedex® Care Notes:
- Diabetes Mellitus Type 2 In Adults
- Diabetes Mellitus Type 2 In Adults, Ambulatory Care
- Diabetes Mellitus Type 2 In Children
- Diabetes Mellitus Type 2 In Children, Ambulatory Care
- Diabetic Gastroparesis
- Diabetic Hyperglycemia
- Diabetic Hyperglycemia, Ambulatory Care
- Diabetic Hypoglycemia
- Diabetic Kidney Disease
- Diabetic Kidney Disease, Ambulatory Care
- Diabetic Neuropathy
Drugs.com Health Center:
Mayo Clinic Reference:
More about glimepiride
- Other brands: Amaryl