Skip to main content

Exenatide User Reviews & Ratings (Page 2)

Brand names: Byetta, Bydureon, Bydureon BCise

Exenatide has an average rating of 6.4 out of 10 from a total of 410 reviews on Drugs.com. 50% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Exenatide

  • Alabama...
  • Taken for 6 months to 1 year
  • September 21, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon since Jan 2013. I have been able to stop taking all of my other oral medicines. My blood sugar is great. My doc told me to take the medicine out of the refrigerator 15 minutes before mixing. Has helped with the bumps. Once per week is GREAT."

8 / 10
Was this helpful?YesNo
55 Report
  • Colld...
  • May 2, 2015

Byetta (exenatide) for Diabetes, Type 2 "My endocrinologist gave me a sharp warning a year ago. He told me that if I did not lose weight immediately I would become diabetic and have to go on insulin. Through sheer force of will and terror I lost a lot of weight last year. My blood tests were looking fantastic. Unfortunately I just could not lose more weight this year. My doctor put me on Byetta a month ago. My mind is made up not to eat sugary foods or highly refined carbs. I have lost 4 kgs in a month. Since April last year I am 17kgs lighter and feel so many good effects. I am determined to lose another big chunk of weight this year. The Byetta definitely takes away the appetite. I literally can't eat too much. I think it's great. The side effects are minimal."

Was this helpful?YesNo
47 Report
  • Betsyde
  • Taken for 6 months to 1 year
  • May 24, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon since November 2012 and 2000 mg metformin a day. I am pre diabetic, have hypothyroidism and polycystic ovarian syndrome variance. After much difficulty, this medicine has been a lifesaver! I have lost 51 lbs to date (235 to 184) and am feeling great! My a1c went from 6.5 to 5.7 in three months. I get new lab results next week. I did have side effects in the beginning but I stuck with it and it is fine now. No more nausea. Some diarrhea but I also have Irritable Bowel Syndrome. Good luck to anyone out there dealing with this."

10 / 10
Was this helpful?YesNo
54 Report

Frequently asked questions

  • Anonymous
  • Taken for 1 to 6 months
  • September 8, 2012

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon for approx. 8 weeks now. My morning glucose has gone from 230, down to 105 now. I don't really feel any different with it lower but it is probably helping my kidneys to preform better. As far as the larger needle, I started injecting in my thigh and barely feel it. At first I was ravenous and was really surprised, now sometimes I have to remind myself to eat and eat much smaller portions. I've lost 16 lbs. and I'm at the lowest weight I've been in 35 years. When I first started, I would feel nausea and throw up for no reason when my dose was wearing off, the doctor said she had never heard of that complaint before! My only complaint is that the medicine seems to stick to the vial and I really have to beat on it!"

10 / 10
Was this helpful?YesNo
56 Report
  • UserU...
  • July 6, 2021

Bydureon BCise (exenatide) for Diabetes, Type 2 "I get so frustrated with these pens I almost feel like crying at times! I'm trying so hard to work with my doctor and am fully willing to deal with some side effects with this med in order to give it a fair attempt. But I've gone through so many pens these past 3 months where I follow the instructions exactly as they provide...only for the dang pens to get stuck. The needle's injected, but the plunger does not budge. No (or very little) liquid gets injected. I move the pen around, tap on it, push it further into myself...nothing. And it's not like I can just take it out and re-inject myself. The moment I do so, the liquid then starts to shoot out of the needle and the dose is completely wasted. I feel so defeated! :( I once broke one of the pens apart to gain access to the liquid and tried using my own syringe...however the liquid is way too thick for my syringes and only clogged the needles rendering them useless. 3 months in and I've missed 4 or 5 weekly doses. :( :("

1 / 10
Was this helpful?YesNo
19 Report

Are you taking this medicine?

  • Anonymous
  • April 14, 2012

Byetta (exenatide) for Diabetes, Type 2 "I have been on Byetta for 10 weeks now and lost 18kg. Been on Byetta. It's the best thing that has happened to me. I weighed 150kg in January and was gaining weekly. My endocrinologist gave it to me so I could lose weight for a hip replacement, but now my hip feels 60% less pain, so might not have to have the hip replacement soon. The only thing I can say is get your mindset right as to your portion size with a low carb diet, no alcohol, fizzy drinks or sweets if you trying to diet. Also I am a type 2 and was on Glucovance until Byetta. Now my reading is 5.1 and dropping slowly. Please understand I use it for weight loss hoping to get off medicines...so far so good."

10 / 10
Was this helpful?YesNo
56 Report
  • grate...
  • Taken for 1 to 2 years
  • March 6, 2014

Bydureon (exenatide) for Diabetes, Type 2 "I've been on Bydureon for a year now. My HbA1c is running between 5.5 and 6.6. Every once in a while I will have nausea. But rarely. The diarrhea isn't to bad and counter that with Imodium ad. Weight lose has stopped. Was 295lbs when I first started Bydureon a year ago. I am now stuck at 275. But Thanksgiving and Christmas, I'm sure didn't help any. I'm back on my strict diet. Of salads and turkey and tuna. So I'm sure to lose more weight, from where I don't know because I'm in decent shape. My blood sugars run from as low as 74 all the way up to 200. But mainly stay around 80 to 130. It has gotten more expensive for me. I was paying $20 a month. Now it has jumped to $150 a month."

10 / 10
Was this helpful?YesNo
49 Report

More FAQ

  • flute...
  • Taken for 6 months to 1 year
  • November 3, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon since March 2013. Started initially with Byetta Sept. 2012 but had to make a switch because of nauseousness. Bydureon has been so much easier to deal with and I haven't been nauseous. The differences I found were 1) I feel hungrier with Bydureon (not as much appetite supression) so I just have to make sure I'm using good portion control; 2) I'm not losing weight as quickly as I did on Byetta. It could be that I'm reaching goal weight and it's harder to lose the last little bit. Current loss 82 lbs. As far as BG numbers, I have gone from morning fasting # of 160s/170s before Byetta/Bydureon to 80s/90s now. I've also gone from 2000 mg metformin daily to 1000 mg daily."

10 / 10
Was this helpful?YesNo
50 Report
  • Pilates
  • Taken for 1 to 6 months
  • February 7, 2020

Bydureon BCise (exenatide) for Diabetes, Type 2 "I have used Bydureon BCise for 5 weeks and so far I have had 3 pins malfunction . Very annoying . I spend 30 minutes on the phone answering the same questions and then they send an envelope to put the pin in and mail back by fed x . I have to go to the nearest fed x to mail back and then to the pharmacy to pick up a new pack . This needs to be fixed"

9 / 10
Was this helpful?YesNo
25 Report
  • Deborah...
  • Taken for 5 to 10 years
  • March 16, 2013

Byetta (exenatide) for Diabetes, Type 2 "I have been on Byetta for 5 years. My A1C was 8 when I started Byetta and is now 5.6 the past 4 years. I have been able to lose 63 pounds without any diet plan, just slowly lost this weight. I am now on half the dosage of other diabetic medications I am taking and reduced my blood pressure medications to 1/4 the dose . The only problem I have with Byetta is nausea while waiting to eat."

8 / 10
Was this helpful?YesNo
51 Report
  • Tenicua
  • Taken for 1 to 6 months
  • August 19, 2019

Bydureon (exenatide) for Diabetes, Type 2 "Hey guys! Use it in the lower abdomen. Then rotate each time. This stuff works. And yes there are side effects. It drains energy out of ya. But you will lose 4 pounds each month. And if you are already going thru some drama .. being on this medicine intensifies the feelings you have. Sorry, but it’s the truth. I’ve been on it for 3 months. Start weight 206.. now I am 195. I’m 43 and so glad I’m on something that actually works to get weight off. I cried about this situation and here I am. It works. I wish my insurance would pay for the ozempic tho. Well anyway, have a great one guys! . I’m praying for each and every one of you. Blessings"

9 / 10
Was this helpful?YesNo
26 Report
  • Hulagal
  • Taken for 1 to 2 years
  • July 17, 2013

Bydureon (exenatide) for Diabetes, Type 2 "I was on Byetta for 5 years and switched to Bydureon. Been on Bydureon for almost 1 1/2 years. I usually have some difficulty eating the first day of my shot. I get a funny taste in my mouth and no appetite. I eat so my sugar does not drop too much. I have maintained my weight to about 125 and feel great. Most people don't think I'm diabetic. Walking everyday helps so much. And yes, I do get a lump from the injection. Just make sure you are not injecting into the same area. I alternate each side of my stomach. My Endocrinologist had me put my hand over my belly button and he said I should be injecting on either side. It helped give me a reference since I was doing it too close to the belly button. Also I shake the medicine for about 4 minutes."

10 / 10
Was this helpful?YesNo
48 Report
  • GGirl
  • July 28, 2019

Bydureon BCise (exenatide) for Diabetes, Type 2 "I wouldn't know if the medication works or not because after trying to use 4 different pens from two separate boxes, I have yet to get a pen to work. The medicine either comes out when I take the orange lid off, or it is all over my stomach when I remove the pen. The cost is too exorbitant to have this waste."

1 / 10
Was this helpful?YesNo
26 Report
  • Lani
  • July 21, 2015

Bydureon (exenatide) for Diabetes, Type 2 "I had liver damage from Lisc/hcl so I became type 2 diabetic ..My M.D. put me on Bydureon to take the load off my liver to allow it to heal...I have dropped 18 lbs , my nurse pract/bydur rep taught me how to eat properly WATCH YOUR CARBS...NOT CALORIES!!! I was only eating between 1000-1400 calories a day and gaining weight. My NP taught me about carbs my 120 calorie snack had 110 carbs in it!!! As a diabetic I was only to shoot for 150 carbs a day..I did this... the weight is melting off my liver enzyme test came back perfect! after two years of fighting!!.. the Bydureon is working!! it did give me some heart burn,diarreah ,and lumps at injection site...but I feel this is worth it !! I have been on it for 6 weeks now! count your carbs!"

10 / 10
Was this helpful?YesNo
41 Report
  • Aries...
  • July 21, 2015

Bydureon (exenatide) for Diabetes, Type 2 "My experience has being great. I have lost about 20 pounds in 2 months. Side effects: just mild nausea if I don't eat, loss of appetite. Glucose levels of 107 in the mornings vs 160. I do have the bumps on the injection sites. I chose my belly but I think I need to change sites. I am really happy with the results and would not change it for anything else. I was having a really hard time losing weight before and now it became really easy. My doctor also put me on a lactose free diet and it s working wonders for me. No more upset stomach or bloating."

9 / 10
Was this helpful?YesNo
41 Report
  • Lindt...
  • Taken for 2 to 5 years
  • April 18, 2015

Bydureon (exenatide) for Diabetes, Type 2 "I have used Bydureon for 2 years. It has been a God send. My A1C has went from 10 to 5.2. I watch my diet and exercise daily. Over the holidays I did eat more sweets than usual and my A1C was 5.8. So it has been a wonderful drug for me. I don't use insulin anymore. the only complaint I have is I get hot flashes like menopause. I am well over menopause by my hormone tests. I wonder if I am the only one with these hot flash symptoms? I call them my "Bydureon hot flashes""

10 / 10
Was this helpful?YesNo
42 Report
  • Maril...
  • November 10, 2016

Bydureon (exenatide) for Diabetes, Type 2 "I started Bydueron 10 weeks ago. I was fine the first 6 weeks. On week 7, I became extremely ill. Vomiting, explosive diarrhea, gas pains and bloating like never before, long flatulence every few minutes (how embarrassing!), and sulfur-tasting belching (like rotten eggs). Endo dr. said it wasn't the med. I went to my primary doctor because I wasn't sure if it was a virus. All of my tests came back negative. Third week, same thing. I decided not to take the injection and notified endo. She told me to stop metformin and resume shot. Last week, had shot and condition worsened. She finally told me to stop the injections. It's been four weeks of suffering. Not worth it! This stuff is poison to me!"

1 / 10
Was this helpful?YesNo
36 Report
  • HaydeeC
  • Taken for 1 to 6 months
  • March 9, 2017

Bydureon (exenatide) for Diabetes, Type 2 "I started on the weekly injection after oral hypoglycaemic tablets stopped controlling my Blood Sugar Level (BSL). The effect was pretty much instant. Within two weeks my BSL had normalised and I had lost weight. I am still on track and have lost 6 kegs in 3 months. Some tips from me: Take the injection out of the fridge at least 30 minutes prior to mixing and injecting it mixes better and doesn't hurt to inject. Take an anti-nausea to medication 30 minutes prior to the injection and take the injection at night before you go to bed. Eat small regular food 6 times a day with high fat (fat has no glycaemic index) moderate protein(90gm /day) and low carb (<100gms day). All this has helped me feel and look good, lose weight and have normal BSL."

9 / 10
Was this helpful?YesNo
35 Report
  • ALV
  • Taken for 1 to 6 months
  • February 9, 2014

Bydureon (exenatide) for Diabetes, Type 2 "I started on this medication 4 months ago. Followed instructions and take the Bydureon out of the refrigerator the night before. My wife gives the injection as I would never be able to do this myself. The needle is huge! It burns going in and the nodes take many weeks to go away. To this day heartburn, painful gas in lower abdomen, pain at base of neck, very low energy level where I must lay down about every three hours. I am 5'9" 172lbs. I walk 40 minutes on treadmill every morning and do jumping jacks and burpees for exercise. My A1c went from 8 to 8.3 on third visit to Dr. Waiting to see what the numbers will be next week. Just this last week my nipples got swollen, enlarged and are very painful."

6 / 10
Was this helpful?YesNo
45 Report
  • Tmit
  • January 1, 2014

Bydureon (exenatide) for Diabetes, Type 2 "I have taken 7 shots. My blood sugars have gone from 250 to 140 in the mornings waking up. I do have 2 knots just on each side of my navel. I have experienced the nausea and feeling sick within 24 hours of the shot. I have lost 12 pounds. That's a lot considering I weighed 188 when I started and I'm at 176 now. I'm 6'2" tall and losing that much weight kind of scares me. I feel a lot better taking the Bydureon and I take 2000 mg metformin daily. This medicine has stabilized my sugar levels in 7 weeks."

8 / 10
Was this helpful?YesNo
45 Report
  • Type...
  • Taken for 6 months to 1 year
  • September 5, 2016

Bydureon (exenatide) for Diabetes, Type 2 "On Bydureon about a year. I'm 57, been diagnosed type 2 Diabetic for about 8 years. On Insulin + Metformin. Doc prescribed this for me originally because I just couldn't get my A1C below 7.0 even though my daily numbers rarely climbed over 130 even right after eating. The Pros: A1C dropped into the low 4's and remains at that level. Lost 20 - 25 lbs and the weight has stayed off. Pen device is not difficult to set up and use once a week, takes about 5 minutes max to do the injection routine and I've only had 1 instance total in a year's time of a pen not working properly. The Cons: HUGE needle that hurts. Bad nausea after injection and occasional itchy hard lumps at injection site. One major B/sugar crash - low 50's."

8 / 10
Was this helpful?YesNo
36 Report
  • Bizzle
  • April 18, 2019

Bydureon (exenatide) for Diabetes, Type 2 "I have been on medication for 4 weeks now and my sugar readings are higher than ever. I’m so confused because everyone is saying theirs have dropped. It’s like my appetite has increased! What could be wrong!"

1 / 10
Was this helpful?YesNo
26 Report
  • Dick...
  • Taken for 2 to 5 years
  • May 16, 2016

Bydureon (exenatide) for Diabetes, Type 2 "I have been on Bydureon for two years and have lost over 30+ pounds along with my sugars now under control. I also take Metformin as an oral as well. In reviewing some of the reviews I agree that in the beginning I had so called lumps but as time has gone by I don't seem to get them any longer. No burning and once in awhile a little bleeding but that can be cleaned away just like when you are getting blood taken. After all you are injecting into the skin. One of the things I do before taking my weekly scheduled injection is taking the kit out of the refrigerator the day before and getting it down to room temperature. Not sure if this has eliminated lumps or burning but there seems to be a difference. Bydureon has been good to me."

10 / 10
Was this helpful?YesNo
36 Report
  • LuvCe...
  • Taken for less than 1 month
  • June 24, 2015

Bydureon (exenatide) for Diabetes, Type 2 "Its been a week and took my second injection. My hungry is practically nothing and i need to remind myself to eat. Now my morning reading is 172 from 207 and after two hours its 135-145 range. I have lost 7lbs in one week! No side effects except some diarrhea. Im feeling better day by day. Switched my diet to less carbohydrates so i do not have a rollercoaster of numbers. Feeling less tired also. Will post more in a week."

8 / 10
Was this helpful?YesNo
39 Report
  • FreidaM
  • August 3, 2016

Bydureon (exenatide) for Diabetes, Type 2 "This is my 3rd review. Just had my A1C checked at my 3 month visit. Started this med with an 8.4 in 3 months it's down to 6.2. This drug has been the only thing that has worked for me in the past 10 yrs. I've been on so many diabetic meds. Last year my a1c was 10.2 got it to 8.4 with farxiga. Since my last weigh in at the dr. I actually had lost 10 pounds. Started this med at 184 now im 174. Still took 3 months to lose 10 pounds. Thats better than a gain though. My only remaining side effects are knots under the skin at injection site. They somethings itch really bad too. Other than that ive adjusted really well."

8 / 10
Was this helpful?YesNo
34 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.