Exenatide Side Effects

Brand Names: Byetta

Please note - some side effects for Exenatide may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Exenatide - for the Consumer

Exenatide

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Exenatide:

Decreased appetite; diarrhea; dizziness; feeling jittery; headache; indigestion; nausea; vomiting; weight loss.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; symptoms of low blood sugar (eg, chills, confusion, drowsiness, fainting, fast heartbeat, increased hunger, increased sweating, irritability, nervousness, severe dizziness, tremor, vision problems, weakness); unusual, severe, or persistent stomach pain or vomiting.

Side Effects by Body System

Metabolic

Metabolic side effects have included hypoglycemia.

Most episodes of hypoglycemia were mild to moderate in intensity and all resolved with administration of carbohydrate. Hypoglycemia was rarely observed in patients treated with the combination of exenatide and metformin and was similar in incidence to patients treated with placebo and metformin. When used as add-on to a thiazolidinedione, with or without metformin, the incidence of symptomatic mild to moderate hypoglycemia with exenatide was 11% compared to 7% with placebo.

Gastrointestinal

Gastrointestinal side effects have included nausea, vomiting, diarrhea, and dyspepsia.

Nervous system

Nervous system side effects have included dizziness, headache and feeling jittery.

Immunologic

Immunologic side effects have included the development of anti-exenatide antibodies.

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