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User Reviews for Exenatide

Also known as: Bydureon, Byetta

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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20%(39)
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17%(32)
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7%(13)
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6%(10)
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Exenatide Rating Summary

7.8/10 Average Rating

195 Ratings with 187 User Reviews

What next?Compare all 155 medications used in the treatment of Diabetes, Type 2.

Reviews for Exenatide to treat Diabetes, Type 2

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Bydureon (exenatide): "4 injections so far and experienced the nausea which initially lasted three days and slowly is backing down. I have no problem with the injection. I don't know if this will help others who develop a lump after their injection but I immediately massage the area on my belly then use ice for about 10 minutes. No rash no pain no lump. I don't know if this is the answer to the lumps or I'm one of the lucky ones but it might be worth a try. My appetite is practically nonexistent. I am experiencing the bloat. I seem to be able to not eat more than seven or eight bites of food without bringing it back up. I also have the most embarrassing huge burps you have ever heard. Also take 2000 mg "Metfartin""

   
8.0

Dillydally. May 23, 2016

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Bydureon (exenatide): "I have been taking Bydureon for several years. Prior to Bydureon my A1C was 9.2. It's now 6.4. It took about 6-8 months but the bumps did disappear. The other side effects are now very minimal. I do get bad GI effects if I over eat...but that's a good deterrent. Over three years and still loving it!"

   
10

Msty May 18, 2016

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Bydureon (exenatide): "I have been on Bydureon for two years and have lost over 30+ pounds along with my sugars now under control. I also take Metformin as an oral as well. In reviewing some of the reviews I agree that in the beginning I had so called lumps but as time has gone by I don't seem to get them any longer. No burning and once in awhile a little bleeding but that can be cleaned away just like when you are getting blood taken. After all you are injecting into the skin. One of the things I do before taking my weekly scheduled injection is taking the kit out of the refrigerator the day before and getting it down to room temperature. Not sure if this has eliminated lumps or burning but there seems to be a difference. Bydureon has been good to me."

   
10

Dick B. (taken for 2 to 5 years) May 16, 2016

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Bydureon (exenatide): "I found the needle extremely thick and the injection painful, some even bled. . After several weeks I began to get one to two lumps at every injection site. These lumps were red warm and extremely itchy. I contacted my physician who lanced one site on my leg. Needless to say I am no longer a Bydureon user."

   
1.0

Suzie G May 7, 2016

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Bydureon (exenatide): "I took my second injection this morning. I have thus far no issue with injection. I do not have a lump like most people seem to have. injection goes well and easy for me. My first side effects after first injection came on day 2 I had terrible nausea for about an 1hr then it went away. I had diarrhea off and on all week and occasional nausea that didn't last long. Im hoping ill adjust to the med and those side effects of away. I did notice a slight decrease in my appetite. I also noticed if i ate to much i would get sick. No weight loss to report yet, but in the first week of injection I notice a big improvement in my blood sugars. Fasting blood sugar was normally 215 it is now 180's. Im hoping for more improvement overtime."

   
5.0

FreidaM46 May 3, 2016

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Bydureon (exenatide): "I took my sixth Bydureon injection yesterday. The great news is my morning BG levels have dropped dramatically, to the 100 range (after being in the 200s). Bad however, I am debilitatingly nauseous 12 to 24 hours after injecting and 4x have thrown up at the 12 hour mark. I am not a fan of the pea sized lumps at each injection area. The first from 6 weeks ago has not shrunk one iota. The three abdomen injections each itched considerably the first week. I switched to injecting front of my legs, which do not itch. My vision, especially computer monitor distance is horrible, but I think that is due to the drop in my overall blood sugar. I am not sure if I can hang with the nausea and would like more info as to whether it will go away in time."

   
5.0

LandofUnland (taken for 1 to 6 months) May 2, 2016

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Bydureon (exenatide): "I am a 360 pound male with borderline type 2 diabetes numbers and no high blood pressure. Kidneys and liver in great shape. Doctor helped me with the first dose on a Friday morning, she walked me through the instructions and injected in my belly. The next morning I was full, no appetite, lethargic, burping rotten eggs, and even got sick (very rare for me). This continued all day andI had to force myself to eat something that night. It is day 3 - sour stomach milder, so so sleep, no appetite, less lethargy but still kind of drained. No bump on my stomach from injection. To be continued....."

   
8.0

Farb in Indy May 1, 2016

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Bydureon (exenatide): "I've been using the pen consistently now for about 10 weeks. I haven't noticed any major side effects. I've only lost about 6 lbs but hey its a work in progress. The best part is my A1C has went down from 10.9 to 9.2 now recently 7.1. Only major issue is the needle is so thick and it hurts, also sometimes the medicine doesn't want to come out so I have to stick myself again and use up another needle tip."

   
9.0

Anonymous (taken for 1 to 6 months) April 30, 2016

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Bydureon (exenatide): "I am on my third injection of Bydureon. The needle is huge and the med burns going in, and bleeds after. No problems with injection site till this week I noticed a small pea-sized bump at the first injection site on my stomach. The first two weeks my morning sugars went up significantly to 190-200. Other side effects are diarrhea (which has resolved this week), bloating and a very uncomfortable full feeling, and some random stomach pain. This week numbers starting to come down to 145-155, but still higher than when on my previous med, Victoza, which made me very nauseous. Not losing weight. In fact, am up 2 lbs. Hope this turns around in the next couple of weeks."

   
4.0

Georgiao55 (taken for less than 1 month) April 27, 2016

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Bydureon (exenatide): "I started this 4 weeks ago, I am ready to quit, my nausea is so bad, it is hard to deal with. I was told it would go away, not! My sugars are running a lot lower and I stopped the actos. I feel like it is a huge rock in my stomach, and looking, smelling, or trying to eat makes me want to gag. I am hanging on one more week. My daughter is a nurse and does my injections, you need to do stomach and pinch up the skin making sure you don't see any veins. I have lost 10 #. and when I lay down to sleep I get heartburn really bad. I can't even sleep, I toss and turn sometimes the whole 8 hours, I am miserable!!!"

   
5.0

taznana April 17, 2016

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Bydureon (exenatide): "This drug is HORRIBLE!!! For the entire month I was on it, my blood sugars were never under 200. I was on Trulicity before this, which is a wonderful medication that is the same type as Bydureon, but my insurance said it wouldn't cover the Trulicity for me anymore unless I tried the Bydureon first (?prior authorization). Well...obviously it sucks so thankfully I'll get to go back on the Trulicity, which made my blood sugars extremely steady (around 110) and I was losing weight...like 2 pounds per week. The Bydureon also hurt horribly to inject and always made me bleed, and the mixing it was a pain in the butt. With the Trulicity, it's all done for you and is almost painless, and I never bled at the injection site."

   
1.0

JenCount (taken for 1 to 6 months) April 6, 2016

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Bydureon (exenatide): "I have been on this for about 5 weeks. The first two weeks, my blood sugars actually increased a bit, then started going down slowly. I was having blood sugars in the 300s after meal and 200s after fasting. They have improved to the upper 100s to low 200s after meals and in the upper 100s after fasting. I know this is still not good, but so much better than it was. I am hoping that these numbers will continue to improve. Alot of people have complained about the shots and side effects. The shots hurt more than the pen needles used with Byetta (which did not work for me), but not that big of a deal. No lumps from them. I've had virtually no major side effects."

   
7.0

123**Valerie** March 26, 2016

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Bydureon (exenatide): "Started Bydureon 2mg in May 2015. It's been 10 months and my A1C is 5.7. I've dropped 60 pounds, went from a size 15 to a size 8, feel great. The nausea realllllly gets me some days and I just can't eat much at all. But, it does do its job. I was on metformin for 2 years before Bydureon and I had constant diarrea. I'll take the nausea over the #2s."

   
9.0

Downwithdiabetes March 18, 2016

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Bydureon (exenatide): "It been taking bydureon for about 4 months. I absolutely love this medicine. After taking metformin for 2 years I requested the switch. So many side effects for me w metformin. The only side effect I notice w bydureon is nausea. In the beginning it was more pronounced but now I just notice it from time to time and it subsides rather quickly. My blood sugars are so much more in control. I have also lost 15 pounds and looking forward to losing more! So glad I switched to this medicine!!"

   
10

Nakita11 (taken for 1 to 6 months) March 14, 2016

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Bydureon (exenatide): "I have only been taking this medicine for two weeks and I love it. My sugars went down right away. from 224-295 to 146-185. I am sure that it will keep going down, My last A1c was 10.6, I can not wait to see the next one. I have some nausea on the day after and a little on day two, but nothing that is horrible. I am still able to eat and I have never thrown up. As for the nodules I rub the area really well after the shot and I do not have any. I use the top of my leg right about my knee and have not had any problems with that either. I love this medicine."

   
9.0

Angela8514 March 4, 2016

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Bydureon (exenatide): "When I can get the pen to work , I get great results.. but I have six pens that won't allow the plunger to dispense the med. This is hopeless."

   
7.0

Pen won't dispense February 8, 2016

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Bydureon (exenatide): "I started taking Bydureon 8 weeks ago. My Blood Sugars were quite erratic. They have been steady at 119 to 154. Four weeks ago I developed a dry mouth. Drinking water all day. I lost 15 lbs. I went to the dentist for my four month clean and a wisdom tooth that was perfectly normal had to be extracted. I stopped taking Bydureon and I no longer have a dry mouth."

   
10

Anonymous (taken for 1 to 6 months) January 31, 2016

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Bydureon (exenatide): "Took byetta for a number of years and started getting sugar "crashes" around 1 to 2 hrs after injecting so had to sugar up to counteract which was rather non productive. There was some fear that I would go low for a week when first starting but that didn't happen. Very stable A1c @ 6.25 like a rock for years. Do not eat full size meals or you can experience pretty nasty nausea when your stomach won't empty and the meal "ferments". I don't call the shot the core drill for nothing. Bleeding should be expected and the time release makes nodules which can work out through the skin surface with a small red bump which lasts up to two weeks. I keep a small led flashlight to eyeball (shine through) the pen ."

   
10

Mulee (taken for 2 to 5 years) January 24, 2016

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Bydureon (exenatide): "This med is horrible! I was on Victosa but my insurance stopped covering it and I was told this was the equivalent. So wrong. This burns horribly going in and uses a large gauge needle. I would rather give myself 5 or more insulin injection a day then this."

   
1.0

Lori j January 20, 2016

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Byetta (exenatide): "As a prediabetic, I am anxious to not hit a "tipping point" into full diabetes. I asked my GP for Vitroza, but could only get insurance to cover Byetta. Three weeks later and 25 pounds less, I am thrilled. I still lap swim 3 times a week and lift weights with no hunger or sweet cravings. Also I inject in my thigh with no side effects. WHEW! Thanks Byetta!!"

   
10

upandready (taken for less than 1 month) December 20, 2015

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Byetta (exenatide): "I used Byetta just to lose weight in 2012. I lost 24pds then and really loved my size. After loosing the weight since I wasn't diabetic I got off of it. So many months later I started to gain the weight back. I decided to start back on it several times but it didn't work with the weight loss . I'm back on it again for a month now and I'm exercising with it but, hadn't dropped any weight. I'm on 10mg. I don't have nausea and when I did it lasted only a couple of days. Any one have any suggestions. Annoynomous"

Annoynomous (taken for less than 1 month) December 19, 2015

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Bydureon (exenatide): "This med is awesome! My a1c and all my other blood work now looks perfect. I have lost 43 pounds in 9 months. The med takes away all of your desire to drink sodas and eat sugary snacks. I found that I got lumps from the shot when I did it in my leg or arm, but not when I do it in my stomach. This is the healthiest I have felt in 5 years. Wish I had been put on this med sooner!"

   
10

Diabetes miracle med December 17, 2015

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Bydureon (exenatide): "I have been on Bydureon for 7 weeks after fighting my doctor about using an inject-able for about a year. I have previously been on Metformin and Xigduo (still taking these) after adding the Xigduo my numbers actually went up. However after adding the Bydureon I have seen an amazing turn around. My fasting glucose has been between 190-210, now it runs between 113-149, depending on what I have eaten the day before. Even better is that I am down about 14 pounds. I told my doctor that I wish I would have agreed sooner, but the medication wasn't available before then. I did have diarrhea in the first couple of weeks but that has gone away. No nausea but I am not nearly as hungry, and most importantly I don't have cravings like before."

   
10

Momotwns (taken for 1 to 6 months) December 17, 2015

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Bydureon (exenatide): "I took this with 3 injections and had the bumps/nodules which were itchy, but with my 4th injection it bled quite a bit and I developed a rash, swelling and bruising. When my doc saw it, she took me off. That night I was very sick in the middle of the night throwing up. I have lost 15 pounds in almost 4 weeks but I do not believe it's the meds...I was still very hungry and it took extreme discipline to do this, in motivation to get off the meds. I will do anything to get back to the weight needed without meds. For now, I'm going to try metformin for the first time."

   
2.0

Mar58 December 16, 2015

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Byetta (exenatide): "Started byetta in mid October 5mgs at first. Moved on to 10mgs from mid November. I almost finished that pen now but I have had no nausea or any other side effects, no weight loss, no difference in my food intake, no diff in my sugar levels. #sad face."

   
1.0

Fatzz December 15, 2015

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