Also known as: Depakote, Depakote ER, Depakote Sprinkles
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Depakote (divalproex sodium) for Bipolar Disorder: I've been on this for 3 weeks now. It has definitely helped my mania. But I'm still very depressed. I've been having very vivid nightmares. Which is strange because I take medicine for those. I also take Ambien and citolopram. I feel like that's a lot of chemicals in my body. I am a drinker but that hasn't seemed to affect anything. My side effects are pretty much exactly what I've been told and read up on. With the exception of the bad dreams. Blood work must be fine. Doc hasn't called. So far so good.
Review by chandlaaz (taken for less than 1 month):
Depakote (divalproex sodium) for Epilepsy: I take this medicine for unexplained seizures. The doctor said they were caused by severe panic attacks. I don't know. It has helped a lot. But the side effects are terrible. Stomach burning, nausea, itching, drowsiness, and much more. I take 1000mg dose.
Depakote ER (divalproex sodium) for Migraine Prevention: Medication was very effective at controlling silent migraines but long term use (more than 10 years) has resulted in a 60 pound weight gain, hair loss and shakiness. Recently have felt very fatigued and confused.
Depakote (divalproex sodium) for Bipolar Disorder: I've been on Depakote for almost a year now. I also take Paxil and Wellbutrin. I gained around 10lbs right from the start. My weight has seemed to have stayed steady the last few months. It's extremely hard to lose it. I have been through a lot of different medications to try and treat bipolar disorder. Even with the medicines I'm on, I'm still depressed and like I don't matter. I'm very sleepy and can lay down and take a nap at any time. I started taking B Complex because I stay so sleepy. My new concern is memory. I can't think of words and dates or names like movie stars very fast and it concerns me.
16 users found this comment helpful.
Depakote (divalproex sodium) for Migraine Prevention: I've always suffered from migraines. I take 500 ER twice a day and gained 16lbs in less than 3 weeks. Since I'm already overweight this caused severe back pain in which I can barely walk and my legs are numb. Works wonders for my migraine but the side effects aren't worth it!
Depakote (divalproex sodium) for Migraine Prevention: I went on Depakote 10 weeks ago. My migraines are no different, but I've gained 25 pounds. That's just crazy! Just switched to propranolol and I think my headaches are getting better.
Depakote ER (divalproex sodium) for Bipolar Disorder: I was recently hospitalized during a manic episode. I have been treated for bipolar going on 20 years ( I'm 41). I have been on Zyprexa and other medicines for anxiety. I am a rapid cycler (frequent manic episodes). I have tried all the meds from A-Z. It's been a awhile since I've tried Depakote, but it's the first thing they put me on in the hospital. It's been 15 days I think it's ok, but when I lay down I feel like weights are holding me to the bed and I seem to get disorientated as to my location in the house ( weird right??). When I get up all is fine again. If anyone has experienced this please share, it would really help. Let's face it "regular" people would freak just having this discussion.
Depakote ER (divalproex sodium) for Bipolar Disorder: Depakote ER is the only medicine I can take for my bi-polar. I have side effects to every medicine I've been on for bi-polar. I can't take the generic. It really bothers my stomach. It doesn't do much for depression. Anything I take for depression makes me manic. I have been on almost medications on the market. I have to learn to live with depression and work my hardest to accept it. I've been living with bi-polar for 38 years. I wish that the brand name wasn't so expensive. It's very hard for me to afford but it must come before food if necessary.
Depakote (divalproex sodium) for Bipolar Disorder: I am on the 500 X 2 ER and people tell me I'm alot more calmer and they see the change, I guess I was on the depressed side of the spectrum. It may also be that I am on Celexa as well. At first I was severely drowsy, but after about seven months in it kicks in. As far as weight gain goes same there no changes. Hair loss? Was already losing it. I have been on lithium and that didn't work, tried Tegretrol as well, come to find out I am allergic, so if I can feel normal and blood tests on liver and kidney comes back fine, hey I will give Depakote 2 big thumbs up with a normal life.
19 users found this comment helpful.
Review by MANIC MISTY :) (taken for less than 1 month):
Depakote (divalproex sodium) for Bipolar Disorder: I have to say some of side effect's to DEPAKOTE ARE TOUGH! But the SIDE EFFECTS TO MY CONDITION IS & could be way worse- So I've been sticking to it & working through The SIDE EFFECTS. It's DEFINITELY a miracle pill- I am only at 3 weeks but I've never felt calm- NO racing thoughts & I feel HAPPIER- & I only have LITTLE anxiety at this time. Before, most weeks I'd end up in ER 3 x's DUE TO A PANIC ATTACK. SIDE EFFECTS: headache, staring, head feels funny like a electric shock, nauseous. My lips & tongue are twitching. Instant cold & clammy feeling.
BUT I LOVE THE CALMNESS & all theses side effects have gone away & I feel like I am living like I've never lived! This medicine is AMAZING.
28 users found this comment helpful.
Depakote ER (divalproex sodium) for Bipolar Disorder: It did help a bit, but you really have to watch out for side effects. I recommend starting a mood journal if you haven't already while taking this medicine. It made me very violent without realizing it.
Depakote (divalproex sodium) for Epilepsy: I have been on Depakote for 15 years, I have epilepsy juvenile myoclonic. No side effects for me. I really like this medicine. It makes me feel safe all the time.
Review by Lindalouthenoo (taken for less than 1 month):
Depakote (divalproex sodium) for Bipolar Disorder: Just been diagnosed with Bi Polar Disorder after goodness knows how many years of episodes. Took my shrink the best part of 2 years to finally diagnose me after many different anti depressants, sleepless nights, racing thoughts, and wild partying till the early hours (sometimes on my own!!!). Just started on Depakote 3 weeks ago initally on 500mg per day which didn't help my mania, now on 500mg morning, and 500mg evening which calms me down, helps me sleep, deals with my irritability and mania, and generally slows me down. I have found that I get eye jolts ... fuzziness, but for the first time in 3 years (when it all started back up!), I am beginning to feel "NORMAL". We'll see how it goes. My consultant has mentioned Lithium also.
24 users found this comment helpful.
Review by Anonymous (taken for 6 months to 1 year):
Depakote (divalproex sodium) for Migraine Prevention: Before Depakote, I've tried vitamin B2, verapamil, and Topamax, but for one reason or another none of them have worked. About 6 months ago, my doctor started me on Depakote. Once I started using it, my daily headaches became a lot more tolerable, but haven't gone away completely, and my severe migraines are at about once a month. However, like many others, there was a noticeable weight gain--about 20 pounds--soon after I started, and it's been pretty steady since. I've also had a bout of depression recently, but it's hard to tell how that's related to the medicine because it isn't my first time. As of right now, I'm not sure the minor benefits are worth the side effects.
divalproex sodium for Bipolar Disorder: I have bipolar 2. Been on this medicine at 500 mgs 2x daily for 12 years. I have not experienced weight gain. I have experienced some hair loss (not enough to be that noticeable as my hair is short and thick. I have experienced hand tremors. My treatment regimen includes gabapentin 200mgs 2x daily, Wellbutrin 150mgs morning and Imovane 0.75mgs at night for sleep. Apart from 2 major crashes approx. 5 years apart from each other this treatment regimen has kept me sane. I do still struggle with bouts of depression and anxiety but am able to cope. Up until past year I have been able to work full time and go to school part time. My treatment plan works for the most part. Tried other Meds but keep coming back to this.
divalproex sodium for Migraine Prevention: Have had migraines for over 20 years. Frequency had increased to more than 15-20 migraines a month. Some would go away with Imitrex or Amerge, some would not. Finally went to see a neurologist (who was a migraine specialist) and we tried several medicines which did not work. She recently prescribed Divalproex Sodium 500 mg, and I have only had one migraine in 4 weeks. Gained 5 lbs but a life without almost daily terrible pain is so worth the possible related weight gain. It is life changing.
Depakote (divalproex sodium) for Bipolar Disorder: This medication has kept me stable for 4 years. I am now 23 and was on 1000mgs at night. I recently went down as my bloodtests came back to high. So I went back down to 700mg and had another manic episode. I am now in the process of finding a antipsychotic to go with it. I have managed to stay 110 lbs for 4 years with a healthy diet and exercise. The only side effects I had were major hair loss, slight tremors, and nausea. All of which have passed within a year
19 users found this comment helpful.
Depakote (divalproex sodium) for Bipolar Disorder: I am a female, first diagnosed at age 19 with bipolar disorder. They first tried Zyprexa which I had a horrible reaction to. The Depakote made me feel like a zombie for months, until it brought me back down to "normal". I stayed on approx 500 mg/day for almost 6 years, then backing down to 250mg until I stopped. I had started to feel depressed at 31 and was put on Lexapro, this led to a manic episode within a few months. Alas I am back on Depakote 500mg/ day. It has saved me. Luckily no significant weight gain besides 10 lbs I lost being manic!) but I do work out and try to eat healthy.
21 users found this comment helpful.
Depakote (divalproex sodium) for Bipolar Disorder: Depakote has been a life saver for me. I take 250mg in the morning and 500mg at bedtime. Weight gain was minimal. 5 lbs that I have lost recently by going on the South Beach Diet. I also take 200mg Zoloft. I sleep okay, but usually need a nap in the afternoon. I look forward to my life now instead of just existing.
24 users found this comment helpful.
Depakote ER (divalproex sodium) for Mania: Depakote has really helped to get me out of the fog of mania. By the same token, so has lithium. I have found, though, that taking both together (by a doctor's suggestion) keeps the number of episodes pretty low. I don't know about anyone else, but sometimes when I get manic, I spiral out of control and actually experience psychosis ( which is terrible). Good medicine though...better with other medicines.
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