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User Reviews for Divalproex sodium

Also known as: Depakote, Depakote ER, Depakote Sprinkles

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Divalproex sodium.

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User Ratings

10
   
21%(33)
9
   
9%(13)
8
   
19%(30)
7
   
17%(26)
6
   
4%(6)
5
   
5%(7)
4
   
5%(7)
3
   
11%(17)
2
   
3%(4)
1
   
12%(18)

Divalproex sodium Rating Summary

6.5/10 Average Rating

161 Ratings with 133 User Reviews

What next?Compare all 85 medications used in the treatment of Bipolar Disorder.

Reviews for Divalproex sodium to treat Bipolar Disorder

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Depakote ER (divalproex sodium): "I've been taking this for a few years and I have severe headaches often along with suffering with low back pain which is constant on my left side and nothing is soothing it. Laying down is excruciating and I'm in the process of running test. This started about 4 months ago and I have been trying to deal with it and hope that it would eventually go away. It's becoming unbearable."

   
4.0

Langelle23 (taken for 2 to 5 years) May 19, 2016

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Depakote (divalproex sodium): "Noticed that depakote improved stability of mood and reduced depression. However, it did not help with mania mood swings. This drug also totally removed my libido. I have never experienced such an inability for sexual activity than while taking this drug. A week after stopping the drug and sexual libido is back. I would avoid this drug if male."

   
4.0

Manuel231 May 15, 2016

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Depakote ER (divalproex sodium): "Depakote has worked great for me. It totally helps with mania. The only medication that clears up my head and makes me feel normal. Also it gets rid of my migranes. The only bad thing is a few side effects. I gained weight and my hair fell out. And I was pretty lathargic at first. Takes a while but once it kicks in I felt like a whole person. I was off of it for a long time and recently was put back on it so going through side effects again but felt a difference rite away."

   
9.0

jamel102065 (taken for less than 1 month) May 13, 2016

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Depakote ER (divalproex sodium): "Honestly this medicine has saved my life! I went from having multiple long lasting episodes of mania to none. Ya i still get the thoughts but im relaxed and able to make conscious choices now that im on it. The only negative side affect is the hair loss but its temporary, but so worth it. Nothing is better than feeling like you are in control of yourself, and this medicine does this for you dont be scared to ask your doctor about it!"

   
10

Susyg (taken for 6 months to 1 year) April 27, 2016

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Depakote (divalproex sodium): "Really intense side effects. Weight gain, zombie like behavior, etc."

   
1.0

rxqp89 (taken for 1 to 6 months) April 22, 2016

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Depakote (divalproex sodium): "I took Depakote 500mg for a week then increased my dose to 1000mg after the next week. The next day I began having terrible stomach pains and pains in my kidneys, especially after eating. I emailed my doctor and he told me the side effects would subside but they didn't. They actually got worse and the abdominal pain would linger all day and night. I also had a hard time sleeping, I would wake up every 1-2 hours and sleep less than 6 hours a night, along with having very vivid dreams. The dreams later got more and more violent/terrifying and I began to fall into a very deep depression, one I had never felt in my entire life. I stopped taking this medication after three weeks. I will never take this medication even if it saved my life."

   
1.0

Bipolar2 April 2, 2016

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Depakote ER (divalproex sodium): "Have been taking this med since 1992 w/ some breaks here and there. I too have been on, what would seem, every med for Bipolar diagnosis. I take 1750mg and also take 400mg of Lamictal (another mood stabilizer which seems to help with the depression) My only issue had been weight gain which remains a problem. 10 years stable, after being hospitalized for 8 months due to manic episode and psychotic break (was only taking Topamax at that time). Would highly recommend."

   
9.0

blessed5# March 11, 2016

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Depakote (divalproex sodium): "Diagnosed 6 years ago as Bipolar 2 after 20 years of being all over the place. crazy ups/back downs but only ever treated for depression, I was put on a variety of medications in the first year that made me so ill, weight gains/losses, irrational thoughts/ideas, constantly felt ill with colds/flu had to keep changing medications and doses to see if they would work, then given Depakote, wow I felt human again within 2 weeks, settled, calm, clear head no side effects, its done wonders for me that no other got close to, I have my life back"

   
8.0

Ekomoon (taken for 2 to 5 years) February 20, 2016

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Depakote (divalproex sodium): "I am not very fond of Depakote. When I took it it didn't improve my moodswings that much. In the beginning it made me nauseous & caused my hair to fall out. No, I didn't go bald, but it thinned out my hair enough that my hairstylist noticed. Eventually, my hair stopped falling out, but I gained a lot of weight & I had very bad tremors & bad coordination. If you do decide to take this medicine make sure your doctor tests your blood regularly. I think you are supposed to have your blood tested every 6 months."

   
3.0

~*Melanie*~ (taken for 6 months to 1 year) February 2, 2016

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Depakote (divalproex sodium): "I have been on depakote for about six months for bipolar II after being taken off lithium, I am feeling more like myself but still feel a slight emptiness and falseness, I am also taking lamotrigene and pregablin for extreme anxiety. I have put on nearly a stone in six months, I am also being tested for ADHD, I am 48 yrs old and have had this from when I was a child, when you have grown up with this you do not know any different until you become very ill, sorry for the rambling not sure if it makes sense. x"

amsay January 15, 2016

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Depakote ER (divalproex sodium): "This drug took me out of a downward spiraling mixed episode, for that I'm thankful. However, being BiPolar II, the initial dosage of 1750 mg. which was never recommended to lower after its effectiveness had been reached, almost put me right back to where I was. I wouldn't recommend this drug if you're on the depressive side of BiPolar, or for any length of time/dosage that the medication isn't even recommended to be used for. I've since switched to Lamictal, will see how it goes."

   
5.0

HappytoB (taken for 1 to 6 months) January 13, 2016

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Depakote (divalproex sodium): "I am honestly the happiest person ever since my Psychiatrist prescribed Depakote for me, NO MORE RAPID CYCLING!! I take two 500mg tablets about 20 minutes minutes before bed and I sleep throughout only waking up when my back aching in pain; I'll save that for my Baclofen and Prednisone post. I do not experience the manic highs as I was once did; however I still have my low days but everyone does! My low days are no where near the days when I on Trileptal or any SSRIs. I was taking Ability and Lithium for a week (this is my experience) I started seeing the world in two-dimensions, sort of like the early Nintendo characters. I freaking out!! That was it. Make sure to get blood tests every months to ensure your Depakote are in line. A "

   
10

dsran87 (taken for 2 to 5 years) December 23, 2015

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Depakote (divalproex sodium): "Best medicine I've been on !!!! Focused,low anxiety,sleeping well no night terrors ."

   
8.0

Happyintexas (taken for 1 to 6 months) December 11, 2015

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Depakote (divalproex sodium): "My doc switched me from Prozac & Abilify to Depakote ER 500mg at bed time. I've been taking Depakote ER 500mg for almost 4 months now. Everyone in my life has noticed a positive change in me. I feel so calm within. My anxiety & insomnia are very much under control now. I'vw suffeerd with bipolar since my teens. I am 38yrs old. Depakote ER 500 has saved my life! I was done with psych meds & ready to just give up! I'm so glad I have such an amazing doc. No more changing my meds. Depakote ER 500mg in combo with Xanax 1mg 3x's per day has me back to feeling like myself again. Also, I don't need to take the xanax everyday or 3x's per day anymore. The Depakote ER 500mg works for numerous disorders I suffer from. I could go on about the pro's of this med."

   
10

Surviver (taken for 1 to 6 months) December 9, 2015

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Depakote (divalproex sodium): "I was recently diagnosed with Bipolar II. This medication has been a life saver (literally) for me. It has helped keep my emotions in check. I took another medication lamicital that caused one continuous headache that never went away. My psychiatrist started me on a low dose of that medication so I wouldn't get a deadly rash. My emotions were all over the place and I was miserable. My psychiatrist put me on Depakote. At first this medication made me sluggish and hungry. I gained 5 lbs in the first 2 weeks. Since then I have laid off the snacks and beverages and have since gotten adjusted to the meds (also taking Zoloft). Three pounds have come off without trying. Each person is different, but this has really worked for me."

   
10

clemsontigergrl (taken for less than 1 month) December 8, 2015

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Depakote (divalproex sodium): "I've taken a lot of meds in 19 years and took Depakote for around 1 yr. Weight gain about same as Lithium. This drug gave me hallucinations at night and freaked me out big time. Beware. I didn't hallucinate before the drug and now that I've stopped it 6 months ago - no Depakote = no hallucinations"

   
3.0

Medbag December 2, 2015

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"I think it works some what. Still feel a little crazy towards people but a little bit more calmer but makes me tired very tired. I was supposed to be on Seroquel but even with good insurance still 500 dollars! But only been on this a week will give it a chance Thanks"

   
6.0

John from Appleton November 13, 2015

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Depakote (divalproex sodium): "I honestly don't know how many stars to give this medication as much as I've never had such an experience. I was in a coma light sleep when my therapist came, I heard myself say "we need to go to the airport" when actually I never said anything at all. I felt drunk waking up, started losing my hearing, it got cloudy. I only took it a month but being in that state of mind frightened me.I gave it up and my hearing is mostly back about 98 percent but my balance and coordination still suffers from the medication but has improved since I stopped it. I was so upset that I called the FDA and reported my experience, I would hate for anyone to go through that.On the plus side? When I was awake and aware and not "drunk" it did help my manic episodes."

   
2.0

Gage Goliath October 6, 2015

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Depakote ER (divalproex sodium): "I've been taking Depakote ER 500mg at night for 2wks now. I'm Bipolar 1. It's amazing! I've slept great! No side effects. No mood swings. I feel very balanced. I've taken many psych meds over the past 13 yrs. Finally! The right med! I say. Give it a chance if U suffer from severe Bipolar, mood swings, anxiety/panic attacks, sleep disorder...etc. This is working. People close 2 me say I'm a lot calmer now. More rational. Were as b4 I'd quickly lash out! Not now."

Jamie STL (taken for less than 1 month) September 9, 2015

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Depakote (divalproex sodium): "I was diagnosed as bipolar 2 20 years ago and use lithium as mood stabilizer. After a period of discontinuation of drug I switch to depakote and after that I have disk herniation problem and ear pain ."

   
1.0

ehsandro September 9, 2015

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"I was just put on divalproex about maybe two weeks ago I found it really helped with my sadness. Before this one I was on tegretol and it was the horrible it made me wanna kill myself my mood swings were out of control. I felt hopeless unwanted and I was raging out of control I almost lost everything cause nobody could or wanted to be around me. So I hope this one helps me now so I can live a somewhat normal life."

   
5.0

den2002 (taken for less than 1 month) August 28, 2015

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"My dose was increased to 500mg. I started out great on the 250mg. I think the 500 is too much for me. I gained 13lbs again, irritable a lot, etc."

   
8.0

aspergirl (taken for 6 months to 1 year) August 28, 2015

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Depakote (divalproex sodium): "I have to say this drug did more harm then good and my body is very dependent on it. In only a year span I started having serious weight and back issues. I have never had any issues with my back but all of a sudden my bones started to get brittle. Then the disc herniations started happening, and like a domino effect entire spine was damaged. I see along of info on children or babies effected with their spine but apparently it can do the same for a grown adult. I was put on this med for anxiety and what my dr thought was bp. Turns out as time goes by dr lowers my depakote and cAme to the conclusion I do not have bp. Great.. Damage done.. Abnormal EEG. , spine damage, and severe chemical dependency .. Lost my hair , my looks, weight ."

   
3.0

Chrissyanddan (taken for 1 to 2 years) August 19, 2015

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Depakote (divalproex sodium): "This was my first medication for Bi-Polar, I'm a 40 year old woman and a long distance runner. This medication was great because it made the rapid thoughts and anxiety go away. However if you're an athlete like I am, I found this difficult as it caused extreme fatigue to the point where I was a couch potato not wanting to do anything. I gained 10 pounds in the first month and found it exhausting to run even a mile where I'm accustomed to running much more. My doctor is switching me to Topamax, today will be my first day taking it and I'm praying for good results."

   
5.0

BellaSN40 July 22, 2015

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Depakote ER (divalproex sodium): "I took this at night per my doctor, and about the 3rd week I noticed a huge change in my energy and I started having severe muscle cramping and weakness. I woke up in the morning feeling beat up and muscle soreness everywhere. It didn't really help with my issue either. I stopped taking it, and 3 days later the muscle soreness was completely gone"

   
3.0

AlliGibby July 7, 2015

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