Home Drugs A to Z D Di Divalproex sodium User Reviews

User Reviews for Divalproex sodium

Also known as: Depakote, Depakote ER, Depakote Sprinkles

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Divalproex sodium.

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10
   
13%(5)
9
   
29%(11)
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16%(6)
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3%(1)
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6%(2)
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13%(5)
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11%(4)
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8%(3)
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6%(2)

Key Statistics

6.6/10 Average Rating

39 Ratings with 27 User Reviews

Compare all 39 medications used in the treatment of Migraine Prevention.

Reviews for Divalproex sodium to treat Migraine Prevention

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Review by Mantis37: User Rating:  
   
9.0

Depakote (divalproex sodium): Depakote was (and still is) a miracle drug for me with my migraines. I used to get one almost every day, and now it's down to just a few small ones every month!

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March 25, 2008 1:34 AM
Review by handclutch: User Rating:  
   
10

Depakote (divalproex sodium): I've suffered with bad migraines as far back as I can remember and finally after 52 years they got so severe I ended up in hospital. A new doctor took my history and decided to try Depakote (500mg) for 2 weeks and then in 2 weeks double the dose. I started with the 500mg and never had to double the dose. This July 2nd 09 it will have been 2 years without any kind of headache. Not even a little one. THANKS Depakote.

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May 1, 2009 12:22 PM
Review by Chelle6769: User Rating:  
   
4.0

Depakote (divalproex sodium): I have tried Depakote for migraines, as well as Childhood Epilepsy. My son has tried it for Bipolar disorder. It can and does make me and my son lethargic, can cause an increase in salivation, causes massive weight gain (from 105 to 155lbs). In my opinion, the possible benefits are not worth the side effects.

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May 11, 2009 7:17 PM
Review by Maggiebxr: User Rating:  
   
8.0

Depakote ER (divalproex sodium): After trying Topamax for months with no relief, I have been on Depakote ER for three months with GREAT relief! I was having migraine headaches 17 out of 31 days a month, now- maybe one a month (taking Axert when I have pain). The only problem I have had is I have gained 10 pounds in less than three months....this is horrible for me, as I could have afforded to have lost 10 pounds when starting Depakote! My Dr. is going to have me try to mis in 25 mg. of Topamax to suppresse the appetite.

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March 7, 2008 4:54 PM
Review by gregw: User Rating:  
   
9.0

Depakote ER (divalproex sodium): I have been on Depakote ER 1000mg for 2 months and it has almost solved my migraine problem. I still get a few slight nagging headaches, which are easy to treat with ibuprofen. The side effects of stomach upset and fatigue seem to be improving. I think I notice some weight gain, maybe too early to tell. So far so good. I'm happy with this medication. My migraines were threating my ability to earn a living and many days were spent in bed. Things are looking up.

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July 14, 2008 11:53 PM
Review by stefaniekelly: User Rating:  
   
9.0

Depakote ER (divalproex sodium): Responded well to this medicine, after failing everything, including Topamax. I had severe motion component with migraine. Could not stand, roll over or lean over without increased pain/pressure. Depakote finally worked after trying many medicines for 2 1/2 months. just don't like the weight gain

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June 10, 2008 7:28 PM
Review by dfbdar: User Rating:  
   
8.0

Depakote (divalproex sodium): After years of migraines which continued to get worse. I was getting them almost everyday, and ending up in the ER several times Depakote has come to the rescue. I tried Neurontin, and Topamax both did nothing. It's been several weeks and no headache...what a relief this has been for me. I am praying this continues to work.

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November 12, 2009 5:49 AM
Review by Anonymous: User Rating:  
   
4.0

Depakote (divalproex sodium): After having migraines for about a year and trying Effexor which made me vomit, this medicine worked miracles for preventing my migraines. However, it made me extremely depressed and even suicidal. I had to get off and switch to Topamax.

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January 11, 2010 7:12 PM
Review by Anonymous: User Rating:  
   
10

Depakote ER (divalproex sodium): I have been on Depakote ER 1000 mg/day for over 7 years now and my once 4 migraines/months have pretty much subsided to less than 4/year. That's a great improvement for me as I've had them for over 45 years. Nothing worked before, just many pain medicines tried, or shots to put me out for a couple of days and the after effects weren't so fun. I would recommend this to anyone with migraines. Ask your doctor.

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February 3, 2009 9:49 PM
Review by Suzy Q: User Rating:  
   
6.0

Depakote (divalproex sodium): 2-1/2 months of low-grade migraine (from old whiplash accident and cervical spine damage). Saw my neurologist (specializes in migraine) and she put me on a steroid pack. Migraine stopped within a day but then started blotching on face and chest, having allergic reaction. After stopping, got HUGE rebound headache. Went in for my 1st time of Depacon via IV, which made me loopy, nauseous, uncomfortable. This happened for 4-5 hours 2 days in a row. Migraine was pretty much gone. Then put on Depakote at night by pill. Made me feel a little loopy but OK. So first night I was restless, nutty dreams but slept. 2nd night woke up at 2 a.m. awake and cleaned house, folded clothes, etc. Not tired yet at 5 pm.

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July 27, 2009 4:40 PM
Review by csb8136: User Rating:  
   
9.0

Depakote (divalproex sodium): Very good for helping with migraines but if you're prone to weight gain, be careful or reconsider. I have gained about 30 pounds in 5 months. I struggle with depression so gaining weight is not something that I'm dealing with in a good way. It came on very quickly and I was already overweight...(Just a word of warning about the weight gain).

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May 5, 2010 1:41 PM
Review by Anonymous: User Rating:  
   
2.0

Depakote (divalproex sodium): I have been on the medicine for three weeks and the headaches are still there. Sometimes worse.

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August 5, 2009 12:53 PM
Review by SFLDiver: User Rating:  
   
9.0

Depakote ER (divalproex sodium): I have been taking Depakote ER for approximately 4 weeks now with good results. Prior to this medication, I was experiencing frequent dull pressure type headaches, some lasting several days, and occasional short duration sharp migraines. Since using Depakote ER, I have had no migraines and only a couple of very mild and short duration pressure headaches. I realize it's only been a short amount of time on this medication, but the relief has been quite noticeable for me. I have also not experienced any sudden weight gain side effects, however, just prior to starting this medication, I commenced a health eating regimen, which has actually caused me to lose several pounds, and which may be contributing to my weight situation.

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September 8, 2009 12:08 PM
Review by Anonymous: User Rating:  
   
3.0

Depakote (divalproex sodium): Just didn't work.

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November 4, 2009 12:02 AM
Review by Kaye Waverly: User Rating:  
   
1.0

Depakote (divalproex sodium): Depakote worked great as a migraine preventative, but caused a weight gain of over 100 pounds in less than 3 months. It also caused non-alcoholic steatoid hepatitis (aka extreme fatty liver). I also now have Type 2 Diabetes. My body was shutting down because of Depakote. If you decide to take it, please, please, please keep up with the blood tests to check liver function and see your doctor immediately if you have sudden weight gain. By the way, after over 12 years, the last 50 pounds of that weight gain is stubbornly hanging on.

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April 23, 2011 3:08 AM
Review by pinkysmommy: User Rating:  
   
9.0

Depakote ER (divalproex sodium): I have been taking this medication for 3 weeks now. I have not had a headache since I started it. I was getting a migraine 3 times a week previously. Topamax did not help me. I am hoping for no serious side effects! This has improved my quality of life tremendously

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May 11, 2010 11:04 AM
Review by Anonymous: User Rating:  
   
3.0

Depakote (divalproex sodium): Depakote twice a day worked for the headache, but made me so anxious that I could barely function. Once a day is not working for headache. Guess I have to try something else.

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September 30, 2010 10:21 AM
Review by kygent: User Rating:  
   
8.0

Depakote (divalproex sodium): I have had migraines most of my 67 years. 5 yrs ago I found a Doctor who prescribed Depakote 250 mg. My migraines decreased from one per month to maybe five in the past five years. Taken in combination with sumatriptan succinate tablets (only when I feel the onset of a migraine) I have a life mostly without pain.

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November 17, 2010 1:43 PM
Review by Sappo: User Rating:  
   
1.0

Depakote ER (divalproex sodium): I would never recommend this medication because of the horrible weight gain side effect. I gained 70 lbs on this medicine while trying to convince my doctor to change my medicine. It didn't really help my headaches either. I finally had to change doctors to get off this. I got on Topamax and the weight just melted off. Depakote changes your metabolism where everything you eat changes to fat. I took it 18 months too long.

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July 17, 2009 2:30 PM
Review by Anonymous: User Rating:  
   
9.0

Depakote ER (divalproex sodium): For two months now, Depakote ER has cured my migraines, which were occurring approximately two to three times a week, lasting between one to three days each. I had some of the blurred vision and trembling side effects, but the worst has been the weight gain, 10 pounds in two months, when I normally never, ever gain weight. I suppose given the choice, I'll choose the weight gain. Wish I didn't have to choose.

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July 1, 2010 7:52 PM
Review by Anonymous: User Rating:  
   
3.0

divalproex sodium: Works good for migraines, but I experienced hair loss.

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February 5, 2009 5:17 PM
Review by Anonymous: User Rating:  
   
10

Depakote ER (divalproex sodium): I've been on Depakote for 2 weeks now. Not one single migraine. I was having them 2-3 times a week, and less severe tension headaches daily. I haven't even had the tension headaches twice now. I have not gained any weight as of yet either.

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August 9, 2011 5:55 PM
Review by Lucy24: User Rating:  
   
10

Depakote (divalproex sodium): For prevention, I give Depakote a 10 . I was having migraines 7 days a week. Mine began at the age of 4 (at least that's when I was old enough to put words to how it felt in my head. Dr. said I'd probably had them long before that). I have genetic and environmental migraines. Lucky me! I was in a test group that tried Depakote to see if it worked for prevention of migraines. I went 14 days without a headache for the first time in 10 years. That was almost 30 years ago. Then the weight gain started. I already had a yoyo weight problem. My weight (at 6' tall for a female) had never gone over 190. On Depakote it skyrocketed to 262 lbs. Not nice! I told my neurologist who told me it was all in my head. Changed doctors taking Topamax now!

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October 21, 2011 11:02 AM
Review by Anonymous: User Rating:  
   
4.0

Depakote ER (divalproex sodium): Fewer side effects than Depakote but nearly no benefit for migraines.

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November 4, 2009 12:04 AM
Review by Joani S: User Rating:  
   
8.0

Depakote ER (divalproex sodium): I have been on Depakote ER for three weeks. I've had 4 migraines during this time, which is less than before the Depakote ER. My GP had me on three different medicines for prevention but the neurologist switched me to Depakote ER. I've had a little weight gain. The problem is I'm on weight watchers and should be losing weight. There have been times where my hands have felt shaky (similar to too much caffeine intake). I think its also effecting my vision. I'm going to call the doctor and ask to switch to something else. Basically its helped reduced my migraine frequency but not enough to live with the side effects.

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September 7, 2011 12:07 PM
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