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Acetaminophen / hydrocodone for Back Pain User Reviews (Page 5)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 5.8 out of 10 from a total of 393 reviews for the treatment of Back Pain. 48% of reviewers reported a positive experience, while 38% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Loralea
  • September 9, 2018

"Every time I get my RX for my Hydrocodone10/325 at my pharmacy it was by the manufacturer Mallinckrodt and this stuff does NOT touch my pain. I have a serious back condition, a fracture, stenosis and arthritis. I had my doctor change my pharmacy to Walgreens and the first time I got my Rx. it was alright and it was not Mallinckrodt. O.K. the last 2 times it is again this Mallinckrodt, so I had changed my pharmacy for nothing. I swear, I will NEVER again accept a RX of hydrocodone by this manufacturer EVER again. It is absolute junk, honestly is there any active ingredients in it? Does the FDA ever check? It did nothing for my pain, no relief whatsoever, it was like I took sugar pills."

1 / 10
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50 Report
  • Ladybug
  • June 9, 2019

"I have spondylolisthesis, stenosis, scoliosis, arthritis, a fracture, and also a cracked tailbone. I am approaching 60 yrs old and I've worked all my life until I became disabled and could no longer due to my serious back conditions. I had to work with severe pain because I refused to take pain meds. before I was classified as disabled. Due to this so called "opioid epidemic" my doctor only prescribes generice Norco 10/325 mg (acetaminophen a d hydrocodone) and only 3 per day. All I ever get is this Mallinkrodt brand and for a year solid I swear it had NO pain medicine in it, IF it had any it was no more than 2 mgs. OK then suddenly about 5 months ago they started to feel full strength again and worked great for my pain, not taking it all away at all but I felt better. I just got my new months prescription and it's BACK the the placebo ones again, the pure JUNK, it does NOTHING for my pain, you definitely KNOW when it's garbage because it doesn't touch my pain and it just feels like it's all tylenol or filler."

2 / 10
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45 Report
  • Harle...
  • Taken for 5 to 10 years
  • November 7, 2020

Norco (acetaminophen / hydrocodone) "For those saying Watson no longer makes their generic norco...... your wrong. Just picked it up for a disabled friend yesterday and it’s Watson. Don’t know why you’d want it tho. Every time I’ve ever taken Watson norco within twenty minutes I’m vomiting."

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34 Report
  • Fibro...
  • November 18, 2015

Norco (acetaminophen / hydrocodone) "I have Fibro, Spinal Stenosis (severe) and Neuropathy, and occasional migraine headaches. I've been taking the Norco 7.5/325 for five years and it works, along with my 90mg of Cymbalta and 10mg Valium x2 a day. I haven't had to ask for an increase in my meds ever. The pain is always there but manageable. I can grocery shop and do light housework daily. I can drive myself with no danger. I have taken myself off the Norco quite a few times. I might go five to seven days without it just to see if I'm addicted. I hurt a lot but even though I have a full bottle in the bathroom I'm able to resist taking them and not get sick."

9 / 10
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65 Report
  • Bob...
  • September 4, 2019

"OMG. I knew it wasn't just me. Prior RX of 10/325 was fine. Refill on 8/23. Started taking 3-4 days later. (I was ahead last month) Nothing. I've been in severe pain for 5 days. No normal side effects, sleepiness, hot flush feeling ( I did a test today. Took 2 then 30min later took 1 via gums) I don't abuse medication and I was a former MA EMT. So 30mg of this and ZERO effect or side effects. I called Walgreens. They don't care. Called FDA, they don't keep track on these issues. Called drug manufacturer. Like they're gonna do anything if they're selling fake pills. Dr. won't write new RX and take pills back. WTH am I supposed to do now? Check out facebook for groups that support pain groups "

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2019

"I'm so sick of all the "Money Takers" "Healthcare Fakers" I am a 48 year old Black female who has been diagnosed with Disc Degenerative Decease, No Cartilage in between lower back spine, and Osteoarthritis. My Bone Dr. told me, I have the back of a 75 year old man, and he doesn't understand how I'm even walking. I have never done drugs, nor have I even taken pain meds for 6 months straight, since being diagnosed in 2017. Generics of acetaminophen with hydrocodone are not the same in no way shape or form. I'm so sick of being treated like an addict or soon to be addict, I'm not ignorant, and the FDA needs to find a better way of handling it's American People and their Rights... If I want to spend $100 on a brand medication, Insurance or NOT!!! I should be able to, as long as I have a legitimate prescription. AUROBINDO PHARM hydrocodone is nothing more effective than maybe, a 500 mg of Ibuprofen."

2 / 10
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43 Report
  • Spike
  • December 2, 2018

"I've been reading a lot of people complaining about the norco 10/325 M367 the Mallinckrodt Pharmaceuticals brand . I totally agree with what everyone is saying about this manufacturer and how these pills make me feel sick to my stomach and do not work nearly as well as Watson brand , I've asked the pharmacist at Walgreens why they have stopped selling watsons and I've been told they are having a hard time getting them into stock, apparently I'm not the only one complaining to the pharmacy about this issue , I'm also hoping to switch and get away from these bogus M367 pills . After 4 back surgeries and a spinal fusion I'm tired of being in pain from subpar medication and the government not looking into what kind of fillers and dosage issues . Good luck to all looking for Watson brand ."

3 / 10
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  • Norco...
  • August 11, 2018

Norco (acetaminophen / hydrocodone) "I have tons of back issues degenerative disk disease, arthritis, bulging disks, scoliosis and who knows what else as my low back has been killing me so I went to the ER and they of course said I’ll give you muscle relaxers and I laughed and said I know for a fact this isn’t muscle related and in the past had Norco for broken bones and when my back gave me severe pain, Thing is I’m on Xanax which I let them know and I just space the two at least 2 hours apart up to 6 hours apart even breaking the 5mg Norco apart. Today I’m reading about being careful if your on Xanax which I take a low dose of .5mg even break them in half to maybe 3/4 of a pill and take it. I’ve never had a problem with either pill, abusers ruin it for us that need these."

9 / 10
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48 Report
  • Pls...
  • Taken for 10 years or more
  • September 10, 2019

"I made the mistake of filling my script at CVS (as opposed to Walgreens, they were out of it, not my regular Walgreens)& ended up with a LUPIN brand of acetaminophen/hydrocodone . Watson worked best, but they are well & truly gone. So, after having taken 1/2 of my 7.5mg (which is typical, I manage this way throughout day) I thought I was coming down with something, feeling nauseated, severe headache, hot/cold sweat, & didn’t associate this with using different brand. My blood pressure was going up & down. I haven’t had a severe adverse reaction from anything before, & have been taking since 2008. Anyone else???? Am I having withdrawals?"

2 / 10
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41 Report
  • Monroe
  • Taken for 10 years or more
  • September 18, 2018

"***Please Read this if you got switched on brands. I have been taking 10/325 Watson brand for 10+ years, I have a serious lower left back herniated disc , L3 The worst pain is in the morning and standing too long. I have been taking 4-6 tablets a day as needed. Walgreens suddenly stopped carrying Watson brand and switched to Mallinkrodt or whatever. I can honestly say first hand, these do NOTHING for my pain but make me mad and wanting more. I know people will say its the same, but its not. A real pharmacist told me the filler is different and may not be as effective for someone like me who has had one brand for 10+ years. I quit going to walgreens and I literally drove from pharmacy to pharmacy all over my city until I found one who said they will always carry Watson. Do not bother calling pharmacies, because they will all lie to you over the phone and not tell you what they use for brand, because its some violation. Just drive around, that was my best advice."

8 / 10
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47 Report
  • Whats...
  • Taken for 10 years or more
  • December 15, 2020

"always got acetaminophen/hydrocodone m366's worked great for managing my pain. Then wally world filled my last RX with these t258 junk medication and snake oil. In the future we all know we have two choices find a drug dealer for relief or the alternative."

3 / 10
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32 Report
  • silly...
  • November 12, 2019

"After just 3 days of being on NORCO 10MG I have to admit that the Mallinckrodt version is flawed. Equal MG dosage does not translate across brands.I was doing fine on Vicoprofen 7.5 Qualitest Brand (AVOID AMNEAL!!!! Like my review above it is not effective).Problem was I need eight of 7.5s a day.My Doctor thought that insurance would not cover that amount of pills so he prescribed the Norco 10 MGs. I would feel relief from the Vicoprofen within 10 minutes. It takes the NORCO at least 45 minutes to start reducing pain. On top of that once it has started working it seems to wear off within 2 hours not the 4 hours it was made to cover. I'm finding that many Pharms are buying these LOWER COST Brands. I have been told that there can be variation of % in doses.I believe that's what we are seeing in many of these brands...where there SHOULD be 10mgs...there might only be 7. Do not accept these cheap imitations."

8 / 10
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39 Report
  • AngieDJ
  • May 26, 2016

Norco (acetaminophen / hydrocodone) "I have herniated disc, osteoarthritis, degenerative disc disease, spinal stenosis, bone spurs, and more...I have been taking Norco 10/325 for 3 months now and have surgery coming up in June...spinal fusion and laminectomy of lumbar L4 L5. Without this medication I would not be able to get out of bed most of my days and am very thankful to have somewhat of a quality of life. I only take the entire 10 occasionally and break them in half to manage my pain. I do occasionally get light headed and nauseated but I have found that I can avoid this by eating small meals throughout the day and drinking lots of water."

8 / 10
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60 Report
  • Happy...
  • Taken for 2 to 5 years
  • October 14, 2018

"I've taken Watson brand Norcos for a few yrs. Spinal fusion and both full knee replacements in last 2 yes. I'm in constant pain daily and w Watson's, it def helps and takes the edge off. Since Walgreens is no longer carrying Watson brand and is now carrying Melencodt brand, I know longer deal with them for pain meds. They are awful! Make me jittery and doesn't last more than an hour of minimal relief if any! I don't know why they did that but they will lose a lot of customers because of it! I wish I knew which pharmacies carry Watson. "

1 / 10
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45 Report
  • Missy
  • Taken for 5 to 10 years
  • July 31, 2019

"Before I was severely injured on the job in 2012, I would hardly take even an ibuprofen. Now my pain meds do include Marco 10/325. I get the yellow ones made by Par Pharmaceuticals. (Endo Co.)HEB carries these. I have had others tell me the yellow ones are better and I thought they were crazy. Until HEB ran out of the yellow narcos and had sum white hydrocodones. I hurt so bad after taking them that I couldn't function the way I need to. HEB had the yellow ones the next time. I asked the pharmacy tech about this and she told me that several of their patients complain of more pain when they run out of the yellow narcos, so HEB decided their patients comfort is more important than saving a few dollars. Now every time I fill my script, if their out of the yellows they make sure to tell me n ask if its ok. Thank u HEB for being so patient centered. I think because of the addiction outbreak, if u complain about the medicine, its in your head or your an addict."

8 / 10
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40 Report
  • DrFee...
  • Taken for less than 1 month
  • July 6, 2019

"I have been taking generic Vicodin for my back pain for 15 years. Once the Government shut down Watson everything is inferior. The only ones that compare to Watson is PAR and RHODES. I was taking TRIS and it was okay but the last 2 times I took them they were rubbish also."

5 / 10
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  • hanging...
  • May 21, 2013

Norco (acetaminophen / hydrocodone) "This little pill saved my life. I fell off a roof 14 years ago and been on Norco for 6 years and they have been great I can almost work normal, I'm an air conditioning man. I can perform almost all my tasks, great pill. Would recommend for anyone."

10 / 10
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74 Report
  • Rusty...
  • Taken for 1 to 2 years
  • April 24, 2021

Norco (acetaminophen / hydrocodone) "I have had work related back and neck pain. I have had surgeries before and generic vicodin worked great. I haven't had any luck with Lupin generic norco. I have half a bottle left and won't take anymore because it doesn't work. I worked in the pharmaceutical manufacturing for decades and have learned that 80 percent or more of all generics are now made overseas. FDA rarely inspects plants and have no legal jurisdiction there. If you want to know more about the quality of your prescriptions, check the book Bottles of Lies or look online for one or more of her interviews."

1 / 10
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  • Phyll
  • Taken for 2 to 5 years
  • November 27, 2018

"The M367 by Mallinckrodt Pharmaceuticals don't work . Most are drugs are outsourced to other countries but keep the US name. The Watson branded 10/325 only ones that work even though bought out couple yrs ago n made in Japan. The Malincrodkt are worthless it doesn't even show up on a drug test. FILED FDA COMPLAINT"

1 / 10
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43 Report
  • Rgano
  • Taken for 1 to 6 months
  • January 12, 2019

"This brand is worthless. Caused vomiting and no pain relief. I’ve been taking hydrocodone’s for 29 years and I had so many different generic brands and never had an issue with any of them but this one. I wouldn’t wish this brand on my worst enemy. Walgreens and CVS has really screwed up by carrying this brand only..."

2 / 10
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42 Report
  • Kkano
  • Taken for 5 to 10 years
  • September 13, 2019

"I came here looking for an answer as to why my pain may have escalated. I noticed a strikingly different effect to these new acetaminophen with hydrocodone tablets. I'm feeling nauseated all the time. I've heard that some opioid manufacturers are changing the excipient, so I figure that is what happened here. I plan to ask my pharmacist. I'm not withdrawing, but my pain is awful lately and I'm noticing a huge change. These don't seem very effective."

2 / 10
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38 Report
  • Roger
  • November 14, 2019

"Have had several different medications for back pain. The gambit of steroids for nerve pain and even tramadol with no success. Received a prescription for this acetaminophen and hydrocodone medication and had it filled at CVS. I was naive upon receiving it and didn't think there would be a difference between generic, and name brand. CVS only provides the Aurobindo Pharma version, (whether you're self pay or insurance), of this medicine which had no affect. I'm self pay so the only factor is price and whether a pharmacy provides a medication. I've heard anecdotal information about how this type of medicine should work for my condition but considering this one didn't I can only assume this Aurobindo manufacturer is failing to produce a quality medicine. I've never heard or read of this manufacturer's version of acetaminophen/Hydrocodone working for anyone. I would not recommend it considering how difficult it is, even with legitimate reasons, to receive a prescription for pain medications. There are other generics with better stories of success"

1 / 10
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37 Report
  • Anonymous
  • Taken for 2 to 5 years
  • April 26, 2015

Norco (acetaminophen / hydrocodone) "I had suffered Degenerative Disc Disease with two bulging discs at L4 and L5 with Annular Tear and Spinal Stenosis since May 2006. No injury or accident. Right side leg went completely numb on me and sent me to the ER; Within a week I had an awesome Dr helping me with this med, Flexeril and Naprosyn. As well as Physical Therapy and Chiropractic Care. I became pain free in November 2006. Then I got pregnant and in December 2010 the pain was so severe that I had to go on Norco & do Physical Therapy again for two months. Needless I went into Pain Mgmnt with an Awesome Dr and of course tried and failed Morphine, Fentanyl, Oxycontin with OxyIR, Neurontin, and this was always reverted back to Norco. Had Spinal Fusion and Norco was what worked."

10 / 10
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62 Report
  • Kanu
  • October 24, 2013

Norco (acetaminophen / hydrocodone) "I'm a former parole officer who suffered a back injury from a parolee assaulting and escaping from jail back in 1989. I had tried everything for relief of severe back flare-ups that occur and the resulting pain I have in my back, legs and neck frequently. Norco was prescribed by my doctor about 3 years ago and I cannot believe the results from this medication. I am very happy that this medication has allowed me to carry on a normal life again."

9 / 10
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69 Report
  • queen...
  • Taken for 10 years or more
  • January 17, 2021

"On this drug for 15 years for nerve damage. No problems until I received a fill with Mallinckrodt. Little relief, lots of side effects. Found "better" brands--these brands are just not the same as in the past (where did THEY go??), but at least they helped. Anytime something helps, it disappears at some point(?) Now I got a fill with Amneal -I hadn't tried those. (I NEVER paid attention to "brands" until Mallinckrodt! Any change before was seamless!!) Amneal has 0 pain relieving properties! Nothing but side effects in a bottle! Cannot take these for another 30 days! Nausea, sweating, HEADACHES- side effects++! What works--anyone??? I have NEVER lost a script, lost my meds, sold my meds, had my meds stolen & I am writing this, so obviously I haven't OD'd!!! Does it matter? Apparently not. Living like this is NO life."

1 / 10
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29 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.