Acetaminophen / Hydrocodone Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Pain

Tablets:
Recommended dose:
Acetaminophen-hydrocodone 300 mg-5 mg: 1 to 2 tablets orally every 4 to 6 hours as needed
Acetaminophen-hydrocodone 300 mg-7.5 mg: 1 tablet orally every 4 to 6 hours as needed
Acetaminophen-hydrocodone 300 mg-10 mg: 1 tablet orally every 4 to 6 hours as needed
Maximum dose:
Acetaminophen-hydrocodone 300 mg-5 mg: 8 tablets daily
Acetaminophen-hydrocodone 300 mg-7.5 mg: 6 tablets daily
Acetaminophen-hydrocodone 300 mg-10 mg: 6 tablets daily

Liquid:
Recommended dose:
15 mL (acetaminophen-hydrocodone 325 mg-7.5 mg) orally every 4 to 6 hours as needed
Maximum dose: 6 tablespoonfuls daily

Comments:
Dosage should be adjusted according to severity of the pain and the response of the patient. Tolerance to hydrocodone can develop with continued use and the incidence of side effects is dose related.

Approved indication: For the relief of moderate to moderately severe pain

Usual Pediatric Dose for Pain

Recommended dosing for children 2 to 18 years of age:

12 to 15 kg (27 to 34 lbs.)--about 2 to 3 years old:
Recommended dose: 3.75 mL orally every 4 to 6 hours
Maximum dose: 22.5 mL daily (in 6 divided doses)

16 to 22 kg (36 to 50 lbs.)--about 4 to 6 years old:
Recommended dose: 5 mL orally every 4 to 6 hours
Maximum dose: 30 mL daily (in 6 divided doses)

23 to 31 kg (51 to 69 lbs.)--about 7 to 9 years old:
Recommended dose: 7.5 mL orally every 4 to 6 hours
Maximum dose: 45 mL daily (in 6 divided doses)

32 to 45 kg (70 to 100 lbs.)--about 10 to 13 years old:
Recommended dose: 10 mL orally every 4 to 6 hours
Maximum dose: 60 mL daily (in 6 divided doses)

48 kg and up (101 lbs and up)--18 years to adult:
Recommended dose: 15 mL orally every 4 to 6 hours
Maximum dose: 90 mL daily (in 6 divided doses)

Renal Dose Adjustments

Dosage adjustments in patients with renal dysfunction should be done cautiously.

Liver Dose Adjustments

Dosage adjustments in patients with liver dysfunction should be done cautiously.

Dose Adjustments

Acetaminophen-hydrocodone should be used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, Addison's disease, prostatic hypertrophy or urethral stricture.

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

Dosage adjustments in dialysis patients should be done cautiously.

Other Comments

Some dosage units may contain up to 325 mg of acetaminophen per unit.

Usual acetaminophen maximum dosage is 4 g per day.

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