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Acetaminophen / hydrocodone for Back Pain User Reviews (Page 4)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 5.8 out of 10 from a total of 393 reviews for the treatment of Back Pain. 48% of reviewers reported a positive experience, while 38% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Annoyed
  • Taken for 10 years or more
  • May 8, 2019

"Refilled my monthly pain meds & since then have had a pain increase as they have switched to Mallinckrodt brand of acetaminophen with hydrocodone, So much so it’s causing me to not be able to sleep through the night. Have found the best brands of acetaminophen with hydrocodone Qualitest, Watson & Par (not sure on Par spelling) to work the best for me personally. Have been on the same dosage for 11 years+. If it’s the exact same drug & same amount of medication why are my pain symptoms so much higher, along with other as I I’m seeing, if everything’s the same? And who’s checking these medicines , does FDA do spot quality tests to see if the active ingredients are the right strength?"

1 / 10
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56 Report
  • Broken...
  • Taken for less than 1 month
  • February 27, 2020

"My medicine was recalled back to Rhodes and Parma pharmaceuticals for testing I am having all the above complaints somethings changed heart racing, no relief, valve problems lethargic, zombie, headaches it’s like the chain on medicine that doesn’t work will relay updates later thank you"

2 / 10
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49 Report
  • Cindy
  • Taken for 2 to 5 years
  • August 12, 2019

"I noticed my pills were a different shape than normal but assumed they will be the same. NOT!!! Aurobindo brand of acetaminophen and hydrocodone DO NOT WORK!! I had been happy with SUN pharmaceuticals brand for about 3 years. I don't know why CVS started giving me Aurobindo brand but I will not be accepting them again. They are absolutely useless. I feel so taken advantage of, and am getting no pain relief for my back issues, fibromyalgia, Ankylosing Spondylitis, etc How can this happen?? I am so angry "

1 / 10
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  • Patsy
  • Taken for 10 years or more
  • December 6, 2019

"I picked up generic Norco refill today (acetaminophen / hydrocodone) rite aid switched to T 259 which is made by Cambra. Cambra started generic Norco early this year. I was taking Mallinckrodt which worked for me. T 259 Cambra acetaminophen with hydrocodone is not working for me. Anyone else taking this brand."

3 / 10
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  • Dudeman
  • Taken for 10 years or more
  • December 19, 2018

"Hello I have had 4 past back surgeries to include disc fusions. As a long time, 20 years on and off, very intelligent opioid user. I know what works for me and what does not. To say all generics are the same is totally incorrect.To make a long story short I have taken every generic norco known to man. A great pharmacist who actually cares about my chronic pain and generic struggle who works for Walgreens has recently began ordering the yellow Qualitest/Par brand for me. They are soooooo much better than any other brand on the market. As close to the old Watson brand as you can get since the crackdown. All pharmacies as well as the large ones can order just about any brand. Just keep moving up the chain when they tell you they can only get the white narcos and you will find a pharmacist that actually understands and cares about your pain control."

5 / 10
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Are you taking this medicine?

  • Texas...
  • Taken for 1 to 2 years
  • March 28, 2014

Norco (acetaminophen / hydrocodone) "Had a double Discectomy on L1 & L2 fourteen months ago that put me in a wheelchair for 3 months. This was due to nerve damage from the two Herniated Discs. After the wheelchair I used a walker for 9 months. Now fourteen months later I am starting to walk with the aid of cane and continuous Physical Therapy. I do still use the walker at the end of the day but am trying to transition to the cane full time. I hope to be able to walk again someday without the help of any aids. During all this time I was and still am in lots of pain but nothing like it was before surgery. The Norco 10/325 made/makes my pain bearable."

10 / 10
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93 Report
  • James
  • May 17, 2019

"Mallinckrodt brand of acetaminophen with hydrocodone (generic norco) does not work. All major Pharmacy’s are switching over to this brand. I have been taking this medication for the past several years and never had a problem until recently . I shared with my pharmacist the reactions to this manufacturer, and she noted it in my chart. Here I am a few months later picking up my RX. I couldn’t remember the Mallinckrodt brand name that caused the issues prior nor did I think I needed to tell the pharmacy ever single time seeing as they had I could not take and my reaction in my notes. After the first dose, again... sick as a dog. I called CVS to ask them the manufacturer I was unable to take, and sure enough, it was the one they gave me, MALLINKRODT!! They apologized and said they have no control over what they get and there’s nothing they could do for me. This is just flat out wrong and what am I suppose to do now? I don’t see how they are able to get away with this. I am reporting them to the FDA, in which I have a feeling is a part of this as well!"

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  • Anonymous
  • Taken for less than 1 month
  • February 15, 2018

Lortab (acetaminophen / hydrocodone) "I've been taking hydrocodone 10/325 with M367 imprint for chronic back pain for 5 years with good pain relief. Pharmacy switched vendors now pills have imprint G 037. I've been taking them as directed for 3 days with no pain relief."

1 / 10
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64 Report
  • Bjano
  • Taken for less than 1 month
  • August 30, 2020

"I've taken this drug generic for norco (acetaminophen/hydrocodone) for many years and I don't know what they have them, they are not the same drug. Throw them in the trash. I wanted to get them tested to see what was in them but they said because I was on medicare and could not. They signed a contract. They did not want to be liable. Be careful be aware. This is not what they say it is."

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  • RonMe...
  • Taken for 2 to 5 years
  • June 10, 2019

"I got the generic acetaminophen with hydrocodone with the imprint m367 (Mallinckrodt Pharmaceuticals). These have maybe equivalent of 1mg hydrocodone, if even that. Been taking other generic and name brands for years 10/325's to 10/600's etc. Immediately began suffering withdrawal once I went on to the Mallinckrodt brand. First thought was the pharmacy had obtained some fake 'pressed' pills. But in reading others comments what is happening is so obvious, the company/resident chemist, is not mixing in hydrocodone into these particular generic brand norco pills. Do not waste your money as they are as good as a sugar pill. The company should be sued and put out of business immediately. This is a flat out conspiracy. FDA needs to investigate, make sure if this happens to you please send in a complaint."

1 / 10
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52 Report
  • SueW
  • Taken for 10 years or more
  • May 9, 2018

Vicodin (acetaminophen / hydrocodone) "I had been on Vicodin off and on for the last twelve years until recently. My doctor will no longer prescribe this for me because of all the addiction news that is going on with the government. I have had 2 spinal fusions in the past 15 years and never abused the drug nor had any addiction problems. It is the only medicine that helped my pain. I have not found anything to replace it. I now take 4 Motrin at a time along with a herbal supplement called Kratom. This lessens the pain somewhat but am still in severe pain at times. I had no noticeable side effects from the Vicodin."

10 / 10
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60 Report
  • Gmato
  • Taken for 10 years or more
  • May 22, 2019

"Have had chronic pain since the 90's and for years I took Watson brand of acetaminophen with hydrocodone and was and still would be fine with it if I could find it. Also took Mallinckrodt brand and it was fine up until recently sometime in the last 4-6 months. They have changed the formula, the pill is smaller and it seems to have a sleeping agent instead of pain reliever. Never have these pills made me tired before in fact just the opposite by controlling pain I could go about my busy day with confidence and ease, now this company has ruined a perfectly good chronic pain reliever and I spend more time in tears due to pain. If anyone can suggest how I can find Watson I would be so thankful."

2 / 10
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52 Report
  • Rina
  • Taken for 10 years or more
  • March 28, 2019

"I have severe back issues, DDD (Degenerative Disc Disease), Arthritis and was in a car accident. I have taken Norco, 10/325 with Watson on it for over 10 years. I took 2 a day and was great, I could work all day, sleep great, I was able to be very productive in my life and career. This Brand is horrible, does not touch the pain, makes me itch, nauseated and bloating, I'm less functional and really irritated. I have pain the majority of everyday. Here where I live almost everywhere has this brand. I wish they had the Activist white watson. I found an old one and "WOW" I could function and that proved it is in fact the other Brand is like a placebo...I'd like to report this I will research how."

3 / 10
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53 Report
  • retired
  • March 2, 2019

"No longer getting pain relief. I'm 70 years old no problems controlling my pain UNTIL recent drug company changes. My Pain level is much higher with the same dosage. Have 2 degenerative discs in upper & lower back, fractured vertebrae mid-back inoperable due to Osteoporosis. I was taking 10-325 twice daily for 6 years that worked well with periodic spinal injections I was functional with minimal discomfort. Now my pain level is thru the roof on the same dosage. PCP had to add Nexium & Probiotic because I'm having stomach problems with this new formula Expected to be made comfortable in my dotage & was managing that VERY WELL ..Now I'm in excruciating pain again & have additional problems to boot. Seniors need the government to step in IMHO"

2 / 10
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53 Report
  • Chris...
  • September 6, 2019

"Wow, I am in shock, I searched for this a year ago and I couldn't find any reviews about bad medication (dud brands of acetaminophen with hydrocodone) and I felt alone. I do not feel alone anymore. I've taken pain medication for multiple health issues and injuries about 12 years. All of a sudden things changed, manufactures changed and the Norco whatever brand the pharmacy switched to and gave me didn't work and gave me horrible side effects. I specifically only liked taking Watson acetaminophen/hydrocodone because it was the only brand that helped with pain, lasted longer and barely any side effects and did not put me to sleep, then all of a sudden Walgreens changed to Tris brand. I laterally felt like I was dying or I was going to have a seizure."

2 / 10
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49 Report
  • Robert...
  • Taken for 5 to 10 years
  • November 12, 2022

"This drug should be outlawed, it’s worthless. It gives absolutely no real pain relief for back pain caused by whatever condition. I try to remember to check at my pharmacy BEFORE filling an Rx for this pain medication, and if this generic is what they are offering their customers, I immediately go to another pharmacy chain. It is actually useless and of no relief to me or anyone else I know has received it. I made the mistake this month and forgot to ask CVS. But they ALL will tell you “they are all the same”, but believe me they are not. Don’t buy it if it is what your pharmacy is offering or you will suffer a whole month with your condition before you can get your doctor to offer a refill on your Hydrocodone - Acetaminophen. Believe me you will regret purchasing this brand name."

1 / 10
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20 Report
  • Sam
  • Taken for 10 years or more
  • September 25, 2020

Lortab (acetaminophen / hydrocodone) "I've been taking lortab for over 30+yrs... It's not helping my pain at all now. I've had 7 back surgeries which helped but not for long. I need advice on what else I can take. I've got a pain management. I need some help"

2 / 10
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39 Report
  • Mcano
  • December 29, 2019

"I'm , on the horrible generic mallinckrodt brand of acetaminophen with hydrocodone it is absolute garbage, doesn't work for the pain gives me fuzzy head, sick feeling, I don't even think this any hydrocodone in it. In the trash it goes , and in pain I stay"

1 / 10
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45 Report
  • Ronnie
  • Taken for 2 to 5 years
  • January 12, 2020

"I am glad I found this I was starting to think it was all in my head. My rite aid recently switched my hydrocodone to the yellow generic camber ones, these give me an upset stomach and really bad insomnia. When I take them I feel like I'm hyped up and yet they don't work as well. I called the pharmacist and he told me rite aid has switched to this manufacturer for now. They act so weird about this medicine that I hate to transfer pharmacies for just that, but I feel that the pills are actually worthless it's like taking a couple Tylenol and getting this upset stomach."

3 / 10
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44 Report
  • TJJ
  • Taken for 2 to 5 years
  • October 7, 2018

"I agree with everyone!There is ABSOLUTELY no way they are putting the whole narcotic amount they are supposed to have in these useless M367 pills (Mallinckrodt Pharmaceuticals brand). Someone with some clout needs to turn this company in to the FDA. I have been on the Watson brand for 4 years,f or a myriad of health problems.T hese meds made me feel dizzy, sick to my stomach, and DO NOT HELP with the pain at all. The Watsons worked, M367 DO NOT.Maybe the Feds are in on it to make us suffer,or maybe the company is scheming narcotic off the books. All I know is these Mallinckrodt Pharmaceuticals M367 DON"T WORK!"

1 / 10
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53 Report
  • ChrisT
  • Taken for 10 years or more
  • March 1, 2019

Norco (acetaminophen / hydrocodone) "I have had Fibromyalgia and RA as well as depression anxiety, low vit D levels, migraines, and chronic fatigue syndrome. My doctor asked if I wanted 10/325 Norco or 5 mg Percocet. The Norco worked better and was less sedating and itchy. I know from the dentist I need 10-20mg Percocet. Norco keeps me awake, functioning ( out of bed, I’m disabled ) but let’s me get up and move around also less addictive. I also take Cymbalta, Topimax, xanax, lunesta, adderall, Norco, Soma, etc."

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50 Report
  • NORCO...
  • Taken for 10 years or more
  • September 18, 2013

Norco (acetaminophen / hydrocodone) "Two major lower back surgeries, was in major pain ! A Doctor told me about NORCO and I tried NORCO with great success for 10 years. I realize that is a long time to take this! I now have pain management special Doctor and have tried other products to stop the pain. I have always came back to the NORCO 10-325 because it did the job for me. NORCO 10-325 gave me my life back. My pain is under control with this product. "

9 / 10
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  • Anonymous
  • Taken for 10 years or more
  • June 23, 2019

"I have been using "Watson" generic name for Hydrocodone / Acetaminophen 10/325, also formally 10/500 Watson / a blue pill as opposed to white variety. Now my local pharmacy uses Mallinckrodt, which does not help my back at prescribed dosage, can anyone HELP?"

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  • KKran...
  • Taken for 1 to 2 years
  • August 13, 2018

Norco (acetaminophen / hydrocodone) "I’ve been taking Norco for about two years. It’s really the only thing that helps my pain. I usually get my script filled at CVS and, lately, I’ve noticed the generic they use is pretty worthless. Takes sometimes double the pills to get just a little pain relief. Recently switched to the M367 generic (Mallinckrodt Pharmaceuticals) at Walgreens and, wow, what a difference. One pill lasts me almost an entire work day whereas the other generic was requiring two to three just to get partial relief. Never really thought there was much difference in generics but I guess there is!"

8 / 10
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  • Loralea
  • September 9, 2018

"Every time I get my RX for my Hydrocodone10/325 at my pharmacy it was by the manufacturer Mallinckrodt and this stuff does NOT touch my pain. I have a serious back condition, a fracture, stenosis and arthritis. I had my doctor change my pharmacy to Walgreens and the first time I got my Rx. it was alright and it was not Mallinckrodt. O.K. the last 2 times it is again this Mallinckrodt, so I had changed my pharmacy for nothing. I swear, I will NEVER again accept a RX of hydrocodone by this manufacturer EVER again. It is absolute junk, honestly is there any active ingredients in it? Does the FDA ever check? It did nothing for my pain, no relief whatsoever, it was like I took sugar pills."

1 / 10
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50 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.