Generic Name: naloxone (nal-OX-one)
Brand Name: Narcan

Narcan is used for:

Completely or partially reversing the effects of narcotics. It may also be used to diagnose overdose of narcotics. It may also be used for other conditions as determined by your doctor.

Narcan is a narcotic antagonist. It works by blocking opiate receptor sites, which reverses or prevents toxic effects of narcotic (opioid) analgesics.

Do NOT use Narcan if:

  • you are allergic to any ingredient in Narcan

Contact your doctor or health care provider right away if any of these apply to you.

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Before using Narcan:

Some medical conditions may interact with Narcan. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart disease or a history of substance abuse

Some MEDICINES MAY INTERACT with Narcan. However, no specific interactions are known at this time.

Ask your health care provider if Narcan may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Narcan:

Use Narcan as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Narcan is usually given as an injection at your doctor's office, hospital, or clinic.
  • Do not use Narcan if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss a dose of Narcan, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Narcan.

Important safety information:

  • Narcan may cause dizziness, drowsiness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Narcan with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • If you experience a return of symptoms (such as drowsiness or difficulty breathing), contact your doctor immediately.
  • Narcan should be used with extreme caution in NEWBORNS of women who may have had dependency on narcotics; opioid withdrawal may occur.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Narcan while you are pregnant. It is not known if Narcan is found in breast milk. If you are or will be breast-feeding while you use Narcan, check with your doctor. Discuss any possible risks to your baby.

If you are addicted to narcotics and are given Narcan, you may experience WITHDRAWAL symptoms, including abnormal skin sensations; anxiety; diarrhea; fever; goose bumps; nausea; pain; rapid heartbeat; rigid muscles; runny nose; seeing, hearing, or feeling things that are not there; shivering or tremors; sneezing; sweating; trouble sleeping; and vomiting.

Possible side effects of Narcan:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Change in mood; increased sweating; nausea; nervousness; restlessness; trembling; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dizziness; fainting; fast or irregular pulse; flushing; headache; heart rhythm changes; seizures; sudden chest pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Narcan:

Narcan is usually handled and stored by a health care provider. If you are using Narcan at home, store Narcan as directed by your pharmacist or health care provider. Keep Narcan out of the reach of children and away from pets.

General information:

  • If you have any questions about Narcan, please talk with your doctor, pharmacist, or other health care provider.
  • Narcan is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Narcan or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Narcan. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Narcan. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Narcan.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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