Generic Name: minocycline (MIN-oh-SYE-kleen)
Brand Name: Minocin

Minocin is used for:

Treating certain infections. It may also be used with other medicines to treat severe acne. It may also be used for other conditions as determined by your doctor.

Minocin is a tetracycline antibiotic. It works by slowing the growth of certain bacteria and allowing the body's immune system to kill them.

Do NOT use Minocin if:

  • you are allergic to any ingredient in Minocin or to other tetracyclines (eg, doxycycline)
  • you are taking acitretin, isotretinoin, or a penicillin

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: Flashback: FDA Drug Approvals 2013

Before using Minocin:

Some medical conditions may interact with Minocin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have kidney or liver problems, an autoimmune disorder (eg, lupus), or the blood disease porphyria

Some MEDICINES MAY INTERACT with Minocin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Acitretin, anticoagulants (eg, warfarin), digoxin, ergot alkaloids (eg, ergotamine), isotretinoin, or theophyllines because the risk of their side effects may be increased by Minocin
  • Oral contraceptives (birth control pills) or penicillins because their effectiveness may be decreased by Minocin
  • Medicines that may harm the liver (eg, acetaminophen, methotrexate, ketoconazole, isoniazid, certain medicines for HIV infection) because the risk of liver side effects may be increased. Ask your doctor if you are unsure if any of your medicines may harm the liver

This may not be a complete list of all interactions that may occur. Ask your health care provider if Minocin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Minocin:

Use Minocin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • An extra patient leaflet is available with Minocin. Talk to your pharmacist if you have questions about this information.
  • Take Minocin by mouth with or without food.
  • Swallow Minocin whole. Do not break, crush, or chew before swallowing.
  • Drink plenty of fluids with Minocin to wash it down. This will also help to decrease the risk of throat irritation from Minocin.
  • Do not eat or drink calcium-rich foods (eg, milk or other dairy products, calcium-enriched juices) or take an antacid that has aluminum, calcium, or magnesium in it; bismuth subsalicylate; colestipol; iron; urinary alkalinizers (eg, sodium bicarbonate); or multivitamins with minerals within 2 hours before or 2 hours after you take Minocin.
  • To clear up your infection completely, take Minocin for the full course of treatment. Keep taking it even if you feel better in a few days.
  • Minocin works best if it is taken at the same time each day.
  • If you miss a dose of Minocin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Minocin.

Important safety information:

  • Minocin may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use Minocin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do NOT take more than the recommended dose or take for longer than prescribed without checking with your doctor.
  • Minocin may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Minocin. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Long-term or repeated use of Minocin may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Minocin only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Mild diarrhea is common with antibiotic use. However, a more serious form of diarrhea (pseudomembranous colitis) may rarely occur. This may develop while you use the antibiotic or within several months after you stop using it. Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Tell your doctor or dentist that you take Minocin before you receive any medical or dental care, emergency care, or surgery.
  • Do not receive a live vaccine (eg, measles, mumps) while you are taking Minocin. Talk with your doctor before you receive any vaccine.
  • Be sure to use Minocin for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Hormonal birth control (eg, birth control pills) may not work as well while you are using Minocin. To prevent pregnancy, use an extra form of birth control (eg, condoms).
  • Minocin may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Minocin.
  • Lab tests may be performed while you use Minocin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Minocin should not be used in CHILDREN younger than 8 years old. Using Minocin in CHILDREN younger than 8 years old or in women during the last half of pregnancy may cause a permanent change in the tooth coloring of the child.
  • PREGNANCY and BREAST-FEEDING: Minocin has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Minocin while you are pregnant. Minocin is found in breast milk. Do not breast-feed while taking Minocin.

Possible side effects of Minocin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; drowsiness; indigestion; light-headedness; loss of appetite; nausea; sore mouth, throat, or tongue; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; blurred vision; change in the amount of urine produced; dark urine; fever, chills, or persistent cough or sore throat; hearing problems; joint pain or swelling; moderate or severe skin reaction to the sun; muscle pain or weakness; pale stools; rectal or genital irritation; red, swollen, blistered, or peeling skin; ringing in the ears; seizures; severe or persistent diarrhea; severe or persistent headache; shortness of breath; stomach pain or cramps; swollen glands; symptoms of pancreatitis (eg, severe stomach or back pain with or without nausea or vomiting); trouble swallowing; unusual bruising or bleeding; unusual tiredness or weakness; vaginal irritation or discharge; watery diarrhea; white patches in the mouth; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Minocin:

Store Minocin at room temperature, between 68 and 77 degrees F (20 and 25 degrees C), in a tightly closed, light-resistant container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Minocin out of the reach of children and away from pets.

General information:

  • If you have any questions about Minocin, please talk with your doctor, pharmacist, or other health care provider.
  • Minocin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Minocin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Minocin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Minocin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using Minocin.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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