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Minocycline Pregnancy and Breastfeeding Warnings

Minocycline is also known as: Dynacin, Minocin, Myrac, Solodyn, Ximino

Minocycline Pregnancy Warnings

Minocycline has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of embryo and fetotoxicity, including toxic effects on skeletal formation. There are no controlled data in human pregnancy. Minocycline crosses the placenta and may cause fetal harm. Congenital anomalies including limb reduction have been reported rarely during postmarketing experience. When used during tooth development (second half of pregnancy) tetracyclines may cause permanent yellow-gray-brown discoloration of the teeth and enamel hypoplasia. Minocycline is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk. Pregnant patients or patients who become pregnant during minocycline therapy should be advised of the potential hazards to the fetus.

Minocycline Breastfeeding Warnings

Minocycline is excreted into human milk. Theoretical risks of dental staining and inhibition of bone growth exist but are unlikely. Tetracycline, a related drug, is considered compatible with breast-feeding by the American Academy of Pediatrics. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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