Ibandronate

Pronunciation

Generic Name: ibandronate (EYE-ban-DROE-nate)
Brand Name: Boniva

Ibandronate is used for:

Treating osteoporosis (weak bones) in women who are past menopause. It may also be used for other conditions as determined by your doctor.

Ibandronate is a bisphosphonate. It works by slowing bone loss and allowing new bone to be formed.

Do NOT use ibandronate if:

  • you are allergic to any ingredient in ibandronate
  • you have severe kidney problems or low levels of calcium in your blood

Contact your doctor or health care provider right away if any of these apply to you.

Slideshow: 2014 Update: First Time Brand-to-Generic Switches

Before using ibandronate:

Some medical conditions may interact with ibandronate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have cancer, anemia, asthma, blood clotting problems, kidney problems, or an infection
  • if you have low blood calcium levels, low blood vitamin D levels, nutrient absorption problems (eg, malabsorption syndrome), calcium metabolism problems, or you are unable to take calcium or vitamin D supplements
  • if you have poor dental hygiene or other dental problems, or if you will be having a dental procedure (eg, tooth extraction)
  • if you smoke or drink alcohol
  • if you have had or will be having chemotherapy or radiation treatment

Some MEDICINES MAY INTERACT with ibandronate. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Corticosteroids (eg, prednisone) because the risk of jawbone problems may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if ibandronate may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use ibandronate:

Use ibandronate as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Ibandronate comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get ibandronate refilled.
  • Ibandronate is usually given as an injection at your doctor's office, hospital, or clinic. Contact your health care provider if you have any questions.
  • Do not use ibandronate if it contains particles, is cloudy or discolored, or if the prefilled syringe is cracked or damaged.
  • Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
  • If you miss your scheduled dose of ibandronate, contact your doctor to reschedule it as soon as possible. Do not receive your injection more often than once every 3 months.

Ask your health care provider any questions you may have about how to use ibandronate.

Important safety information:

  • Ibandronate may cause dizziness. This effect may be worse if you use it with alcohol or certain medicines. Use ibandronate with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Follow the diet and exercise program given to you by your health care provider. Talk to your doctor about whether you should take a calcium and vitamin D supplement while you use ibandronate.
  • Talk to your doctor about the use of weight-bearing exercises to help prevent weak bones.
  • Certain fractures of the thigh bone (femur) have been reported in patients using bisphosphonates. It is not known if bisphosphonates contributed to the fractures. Contact your doctor right away if you experience hip, thigh, or groin pain. Discuss any questions or concerns with your doctor.
  • Ibandronate may cause jawbone problems in some patients. Your risk may be greater the longer you take ibandronate or if you have cancer, poor dental hygiene, or certain other conditions (eg, anemia, blood clotting problems, infection, dental problems). Your risk may also be greater if you have certain dental procedures or you are using certain medicines or therapies (eg, chemotherapy, corticosteroids, radiation). Talk to your doctor about having a dental exam before starting ibandronate. Ask your doctor any questions you may have about dental treatment while you use ibandronate.
  • Proper dental care is important while you are using ibandronate. Brush and floss your teeth and visit the dentist regularly.
  • Certain dental procedures should be avoided if possible while you are using ibandronate. Tell your doctor or dentist that you use ibandronate before you receive any medical or dental care, emergency care, or surgery.
  • Worsening of asthma has been reported in patients taking medicines like this one. Discuss any questions or concerns with your doctor.
  • Ibandronate may interfere with certain lab or diagnostic tests that use a bone-imaging agent. Be sure your doctor and lab personnel know that you are using ibandronate.
  • Lab tests, including bone density, kidney function, and blood calcium levels, may be performed while you use ibandronate. These tests may be used to monitor your condition or check for side effects. Your doctor may also want to evaluate you periodically while you use ibandronate to assess the need to continue its treatment. Be sure to keep all doctor and lab appointments.
  • Ibandronate should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using ibandronate while you are pregnant. It is not known if ibandronate is found in breast milk. If you are or will be breast-feeding while you use ibandronate, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of ibandronate:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; heartburn; mild arm, back, leg, muscle, or joint pain; mild flu-like symptoms (eg, mild fever, chills, tiredness, weakness, joint or muscle aches); nausea; pain, swelling, or redness at the injection site; stomach pain or upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; fainting; fast heartbeat; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; unusual sweating; wheezing); change in the amount of urine produced; eye pain; mouth sores; painful or difficult urination; severe bone, joint, or muscle pain (especially in the hip, groin, or thigh); severe or persistent dizziness or headache; severe or persistent heartburn or stomach pain; swelling or pain in your jaw; symptoms of low blood calcium (eg, spasms, twitches, or cramps in your muscles; numbness or tingling in your fingers, toes, or around your mouth); vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms of overdose may include mental or mood changes; muscle weakness, spasms, twitching, or cramps; numbness or tingling in the fingers, toes, or around the mouth; seizures; sluggishness; vomiting.

Proper storage of ibandronate:

Ibandronate is usually handled and stored by a health care provider. If you are using ibandronate at home, store ibandronate as directed by your pharmacist or health care provider. Keep ibandronate out of the reach of children and away from pets.

General information:

  • If you have any questions about ibandronate, please talk with your doctor, pharmacist, or other health care provider.
  • Ibandronate is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take ibandronate or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ibandronate. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ibandronate. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using ibandronate.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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