Generic Name: hydralazine (hye-DRAL-a-zeen)
Brand Name: Generic only. No brands available.
Hydralazine tablets are used for:
Treating high blood pressure. It may be used alone or in combination with other medicines. It may also be used for other conditions as determined by your doctor.
Hydralazine tablets are a vasodilator. It works by relaxing and dilating (opening) the blood vessels in the body, allowing blood to flow through the vessels more easily and at a lower pressure.
Do NOT use hydralazine tablets if:
- you are allergic to nitrates or to any ingredient in hydralazine tablets
- you have problems with the blood vessels of your heart (coronary artery disease) or certain heart valve problems (mitral valvular rheumatic heart disease)
Contact your doctor or health care provider right away if any of these apply to you.
Before using hydralazine tablets:
Some medical conditions may interact with hydralazine tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have blood problems (eg, porphyria), blood vessel problems, heart problems, low blood pressure, low levels of vitamin B6 in your blood, kidney problems, or lupus
- if you have a history of stroke
Some MEDICINES MAY INTERACT with hydralazine tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Medicines that may affect your blood vessels, medicines that treat high blood pressure (eg, diazoxide), or other vasodilators (eg, isosorbide, nitroglycerin) they may increase the risk of hydralazine tablets's side effects. Check with your doctor or pharmacist if you have questions about which medicines may affect your blood vessels.
- Monoamine oxidase (MAO) inhibitors (eg, phenelzine) because the risk of serious side effects may be increased
- Beta-blockers (eg, propranolol) because their risk of side effects may be increased by hydralazine tablets
- Epinephrine because its effectiveness may be decreased by hydralazine tablets
This may not be a complete list of all interactions that may occur. Ask your health care provider if hydralazine tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use hydralazine tablets:
Use hydralazine tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take hydralazine tablets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Take hydralazine tablets on a regular schedule to get the most benefit from it. Taking hydralazine tablets at the same time each day will help you remember to take it.
- Continue to use hydralazine tablets even if you feel well. Do not miss any doses.
- If you miss a dose of hydralazine tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use hydralazine tablets.
Important safety information:
- Hydralazine tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use hydralazine tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Hydralazine tablets may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Tell your doctor or dentist that you take hydralazine tablets before you receive any medical or dental care, emergency care, or surgery.
- Lab tests, including complete blood counts and antinuclear antibody titers, may be performed while you use hydralazine tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Hydralazine tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant while taking hydralazine tablets, contact your doctor. You will need to discuss the benefits and risks of using hydralazine tablets while pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you are using hydralazine tablets, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of hydralazine tablets:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; headache; loss of appetite; nausea; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; decreased or difficult urination; depression; fainting; fast or irregular heartbeat; fever, chills, or sore throat; joint pain; mental or mood changes; numbness of an arm or leg; numbness or tingling of the skin; persistent fatigue or weakness; severe or persistent headache or dizziness; unusual bruising or bleeding; vision changes; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include chest pain; fast or irregular heartbeat; flushing; severe headache; shock.Proper storage of hydralazine tablets:
Store hydralazine tablets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep hydralazine tablets out of the reach of children and away from pets.
- If you have any questions about hydralazine tablets, please talk with your doctor, pharmacist, or other health care provider.
- Hydralazine tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take hydralazine tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about hydralazine tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to hydralazine tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using hydralazine tablets.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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