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U-Seal (Canada)

This page contains information on U-Seal for veterinary use.
The information provided typically includes the following:
  • U-Seal Indications
  • Warnings and cautions for U-Seal
  • Direction and dosage information for U-Seal


This treatment applies to the following species:
Company: Jurox

Veterinary device


U-Seal is an off-white smooth sterile paste containing 65% Bismuth Subnitrate, in a mineral oil vehicle.

U-Seal Indications

U-Seal is a non antibiotic product indicated for closing the teat canal by forming a physical barrier in cows at drying off. This aids in preventing bacteria from entering the teat canal during the dry period which results in a reduced incidence of mastitis.


Administer one syringe into each quarter of the udder immediately after the last milking at drying off. It is recommended that U-Seal be used as part of a herd approach to dry cow management and mastitis control.


As U-Seal possesses no antimicrobial activity, it is essential the teat be thoroughly cleaned, disinfected, and allowed to dry before infusion, and care be taken to avoid contamination of the syringe nozzle.

After the last milking at drying off clean and disinfect the teats with alcohol swabs provided and infuse the entire contents of a syringe of U-Seal into each quarter by inserting the nozzle into the teat and applying gentle continuous pressure to the plunger until the paste is expressed. Do not massage the teat or udder after infusion of the product. It is advisable to use an appropriate teat disinfectant following the infusion.


1. Do not place individual syringes in water.

2. Dry cows off abruptly rather than gradually.

3. Clean teat ends as thoroughly as possible with alcohol swabs and leave air dry.

4. Clean the two teats furthest away and then the two closest.

5. Ensure the teats are clean and dry before infusion.

6. Infuse the teats in the opposite order to cleansing: i.e. the closest two teats first then, the two furthest away.

7. Gently close off the base of the teat streak canal before administering U-Seal.

8. Carefully insert the U-Seal nozzle into the teat streak canal but not to its full length. U-Seal should be infused in the teat streak canal only.

9. Do not massage the quarter after infusion with U-Seal.

10. After infusion, dip teats in teat dip or spray with teat spray and leave cows standing in yard for at least 30 minutes to allow the teat canal to close.

11. Check cows regularly for signs of mastitis during the first week after drying off.

At calving, the seal may be stripped-out by hand or may be ingested by the calf. Ingestion of U-Seal by the calf is safe and produces no adverse effects.


Do not use in lactating cows. If lactating cows are accidentally infused, the seal can easily be stripped out manually. Not intended for treating cows with suspected or confirmed intramammary infection at drying off.


For use in dry cows only. Zero day milk and meat withdrawal when used alone. If U-Seal is administered following an antibiotic infusion, the withdrawal periods for meat and milk for the antibiotic should be observed.


Store between 15 and 30°C. In very cold temperatures U-Seal may become difficult to administer and should be warmed to room temperature. Do not immerse individual syringes in water to warm.

Manufactured By

Jurox Pty Limited, 85 Gardiner Street, Rutherford, NSW 2320, Australia

Imported And Distributed By

Central Sales Limited, 1 - 14 Regan Road, Brampton, ON L7A 1B9, Canada

For technical questions or to report an adverse event call Central Sales Ltd. at 905-840-0800 or e-mail:

U-Seal is a trademark of Jurox Pty Limited

Revised: September 2019

470645 V01



144 syringes of 4g

470635 V01

CPN: 2065002.0

Distributed by CENTRAL SALES LTD.
Telephone:   905-840-0800
Order Desk:   800-387-2522
Local Fax:   905-840-1309
Toll-Free Fax:   888-437-9999
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