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Sustain III Bolus

This page contains information on Sustain III Bolus for veterinary use.
The information provided typically includes the following:

Sustain III Bolus Indications
Warnings and cautions for Sustain III Bolus
Direction and dosage information for Sustain III Bolus

Sustain III Bolus

This treatment applies to the following species:

Company: Durvet

(sulfamethazine)

SUSTAINED RELEASE CALF BOLUS (72 HOURS)

Antibacterial

NOT FOR USE IN HUMANS

KEEP OUT OF REACH OF CHILDREN

Restricted Drug (California) - Use Only As Directed

NADA 120-615, Approved by FDA

EACH BOLUS CONTAINS:

Sulfamethazine (formulated in a sustained release base)

495 grains (32.1 grams)

Sustain III^® Boluses (Sulfamethazine Sustained Release Boluses) are intended for oral administration to beef cattle and non-lactating dairy cattle (See RESIDUE WARNING Statement). Sustain III^® Boluses are indicated for the treatment of the following diseases when caused by one or more of the following pathogenic organisms sensitive to sulfamethazine:

Bacterial Pneumonia and Bovine Respiratory Disease Complex (Shipping Fever Complex) (Pasteurella spp.), Colibacillosis (Bacterial Scours) (E. coli), Necrotic pododermatitis (Foot rot), Calf Diphtheria (Fusobacterium necrophorum), Acute Metritis (Streptococcus spp.).

Sustain III Bolus Caution

This drug, like all sulfonamides, may cause toxic reactions and irreparable injury unless administered with adequate and continuous supervision; follow recommended dosages carefully.

Fluid intake must be adequate at all times throughout the three-day therapy provided by the sustained release bolus.

RESIDUE WARNING: Treated animals intended for human consumption should not be slaughtered for food for at least 12 days after the last dose. Exceeding two (2) consecutive doses may cause violative tissue residues to remain beyond the withdrawal time. Do not use in female dairy cattle 20 months of age or older. Use of sulfamethazine in this class of cattle may cause milk residues. Do not use in calves under one (1) month of age or calves being fed an all-milk diet. Use in these classes of calves may cause violative residues to remain beyond the withdrawal time.

Dosage and Administration

Sustain III^® Boluses (Sulfamethazine Sustained Release Boluses) are designed to be administered orally to beef cattle and non-lactating dairy cattle. (See RESIDUE WARNING Statement). Sustain III^® Boluses should be give according to the following dosage schedule.

No. of Boluses	Animal Body Weight
1	200 lbs
1.5	300 lb
2	400 lbs
2.5	500 lbs
3	600 lbs
3.5	700 lbs
4	800 lbs
4.5	900 lbs
5	1,000 lbs

This bolus may be divided for a better approximation of the correct dose; however, care should be taken not to crush the bolus. Care should also be taken to ensure the entire dose has been swallowed by the animal. Observe animals following administration to ensure boluses are not regurgitated. Lubricate Sustain III^® before dosing animals.

Sustain III^® Boluses are designed to provide a therapeutic sulfamethazine level in approximately 6 hours and persist in providing this level for 72 hours (3 days). After 72 hours, all animals should be re-examined for persistence of observable disease signs.

If signs are present consult a veterinarian. It is strongly recommended that a second dose be given to provide for an additional 72 hours of therapy, particularly in those more severe cases. The above dose schedule should be used at each 72-hour interval.

Fluid intake must be adequate at all times throughout the three-day therapy provided by the sustained release bolus.

Store at 20°C - 25°C (68°F - 77°F), with excursions permitted to 15°C - 30°C (59°F - 86°F).

SUSTAIN III^® is Registered Trademark of Bimeda, Inc.

Manufactured for: DURVET, INC. Blue Springs, Missouri 64014

www.durvet.com

MADE IN USA

NET CONTENTS:	NDC	Product No.
50 BOLUSES	30798-109-69	1SUS010	8SUS013 Rev. 10/15
100 BOLUSES	30798-109-70	1SUS008	8SUS008 Rev. 10/15

CPN: 1084159.4

DURVET, INC.
100 S.E. MAGELLAN DRIVE, BLUE SPRINGS, MO, 64014

Telephone:		816-229-9101
Toll-Free:		800-821-5570
Fax:		816-224-3080
Website:		www.durvet.com
Email:		info@durvet.com

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