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Sterile Penicillin G Procaine

This page contains information on Sterile Penicillin G Procaine for veterinary use.
The information provided typically includes the following:
  • Sterile Penicillin G Procaine Indications
  • Warnings and cautions for Sterile Penicillin G Procaine
  • Direction and dosage information for Sterile Penicillin G Procaine

Sterile Penicillin G Procaine

This treatment applies to the following species:
Manufacturer: Aspen

Active Ingredient(s): Each mL contains:

Penicillin G procaine

300,000 units

Sodium citrate

10 mg


5 mg


6 mg

Sodium carboxymethylcellulose

1 mg


1.3 mg


0.2 mg

Sodium formaldehyde sulfoxylate

0.2 mg

Procaine hydrochloride

20 mg

Water for injection


Sterile Penicillin G Procaine Indications

For the treatment of cattle and sheep for bacterial pneumonia (shipping fever) caused by Pasteurella multocida; swine for erysipelas caused by Erysipelothrix rhusiopathiae (insidiosa); and horses for strangles caused by Streptococcus equi.

Dosage and Administration

STERILE PENICILLIN G PROCAINE Suspension should be injected deep within the fleshy muscles of the hip, rump, round or thigh. Do not inject subcutaneously, into a blood vessel or near a major nerve. The site of each injection should be changed. Use a 16 or 18 gauge needle, one and one-half (1 1/2) inches long. The needle and syringe should be washed thoroughly before use and sterilized in boiling water for 15 to 20 minutes before use. The injection site should be washed with soap and water and painted with a disinfectant, such as 70% alcohol.

Warm the product to room temperature and shake well. Wipe the rubber stopper in the vial with 70% alcohol. Withdraw the suspension from the vial and inject deep into the muscle. Do not inject more than 10 mL into one site.

The dosage for cattle, sheep, swine and horses is 3,000 units per lb of body weight or 1 mL for each 100 lbs of body weight, once a day.

Continue the treatment for at least one (1) day after the symptoms disappear (usually 2 or 3 days).

Precaution(s): STERILE PENICILLIN G PROCAINE Suspension should be stored in a refrigerator at 36°-46°F (2°-8°C). Protect from freezing.

Caution(s): Exceeding the highest recommended daily dosage of 3,000 units per pound of body weight, administering at recommended levels for more than 4 consecutive days, and/or exceeding 10 mL intramuscularly per injection site may result in antibiotic residues beyond the withdrawal time.

Sensitivity reactions to penicillin or procaine such as hives or respiratory distress, sometimes fatal, have been known to occur in some animals. If signs of sensitivity do occur, stop using the medication and call a veterinarian. If respiratory distress is severe, the immediate injection of epinephrine may be helpful.

As with any antibiotic preparation, prolonged use may result in the overgrowth of nonsusceptible organisms, including fungi. If this condition is suspected, stop using the medication and consult a veterinarian.

Warning(s): Not for use in horses intended for food.

Milk that has been taken from animals during treatment and for 48 hours (4 milkings) after the last treatment with this drug must not be used for food.

Discontinue the use of this drug before treated animals are slaughtered for food 4 days in cattle, 8 days in sheep and 6 days in swine, and 7 days in non-ruminating calves.

Milk withholding time for the product is based on human safety standards. The milk plant may advise additional testing to ensure compliance with industry requirements. It is strongly recommended that the processor be consulted to avoid possible penalties.

Restricted Drug (under California law).

Presentation: 100 mL, 250 mL and 500 mL vials.

NAC No.: 14750750

Telephone:   816-415-4324
Fax:   816-415-4314
Every effort has been made to ensure the accuracy of the Sterile Penicillin G Procaine information published above. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert.

Copyright © 2018 North American Compendiums. Updated: 2018-01-04