Skip to Content

Tyzine Pediatric Nasal Side Effects

Generic Name: tetrahydrozoline nasal

Note: This page contains side effects data for the generic drug tetrahydrozoline nasal. It is possible that some of the dosage forms included below may not apply to the brand name Tyzine Pediatric Nasal.

For the Consumer

Applies to tetrahydrozoline nasal: nasal solution

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning; dry mouth, nose, or throat; increase in nasal discharge; sneezing; stinging.

Seek medical attention right away if any of these SEVERE side effects occur while taking tetrahydrozoline nasal (the active ingredient contained in Tyzine Pediatric Nasal)

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive sweating; pale skin color; pounding in the chest; severe drowsiness.

For Healthcare Professionals

Applies to tetrahydrozoline nasal: nasal solution, nasal spray


Rhinitis medicamentosa (RM) is attributed to chronic swelling of the nasal mucosa resulting in redness, swelling, and rhinitis. RM has been reported after too frequent, prolonged, or excessive doses. Treatment consists of gradual or abrupt withdrawal of therapy and substituting an orally administered decongestant in the interim (if indicated and appropriate).[Ref]

Respiratory side effects have included rhinitis medicamentosa (rebound nasal congestion), transient burning, stinging, or dryness of the mucosa, and sneezing.[Ref]

Nervous system

Nervous system side effects have included headache, weakness, drowsiness, tremors, light-headedness, insomnia, and sweating. Overdosage has resulted in drowsiness in adults.[Ref]


Cardiovascular side effects have included palpitations. Overdosage has resulted in hypertension, bradycardia, rebound hypotension, and a shock-like syndrome.[Ref]


Local side effects have included transient burning, stinging, or dryness of the mucosa, and sneezing.[Ref]


1. "Product Information. Tyzine (tetrahydrozoline)." Kenwood Laboratories, Fairfield, NJ.

It is possible that some side effects of Tyzine Pediatric Nasal may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

More about Tyzine Pediatric Nasal (tetrahydrozoline nasal)

Consumer resources

Other brands: Tyzine

Professional resources

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.