Regranex Side Effects
Generic name: becaplermin topical
Medically reviewed by Drugs.com. Last updated on Jun 29, 2021.
Note: This document contains side effect information about becaplermin topical. Some of the dosage forms listed on this page may not apply to the brand name Regranex.
For the Consumer
Applies to becaplermin topical: topical gel/jelly
Side effects requiring immediate medical attention
Along with its needed effects, becaplermin topical (the active ingredient contained in Regranex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking becaplermin topical:
- Rash or redness of the skin near the skin ulcer
Incidence not known
- Burning sensation at the application site
- unusually warm skin
For Healthcare Professionals
Applies to becaplermin topical: topical gel
Eight of 291 patients (2.7%) on this drug versus 2 of 200 placebo patients (1%) in 20 month clinical trial follow up studies developed cancer; types of cancer varied and all were remote from the treatment site.
Three retrospective postmarketing studies showed an increased death rate from systemic malignancies in patients who had used 3 or more tubes of becaplermin.[Ref]
Common (1% to 10%): Cancer
Postmarketing reports: Increased death rate from systemic malignancies[Ref]
Common (1% to 10%): Erythematous rash[Ref]
More about Regranex (becaplermin topical)
- During Pregnancy
- Dosage Information
- Pricing & Coupons
- En Español
- Drug class: miscellaneous topical agents
1. "Product Information. Regranex (becaplermin topical)." Smith & Nephew, Inc., Fort Worth, TX.
Some side effects may not be reported. You may report them to the FDA.