Regranex Side Effects
Generic name: becaplermin topical
Medically reviewed by Drugs.com. Last updated on Jan 10, 2025.
Note: This document provides detailed information about Regranex Side Effects associated with becaplermin topical. Some dosage forms listed on this page may not apply specifically to the brand name Regranex.
Applies to becaplermin topical: topical gel/jelly.
Serious side effects of Regranex
Along with its needed effects, becaplermin topical (the active ingredient contained in Regranex) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking becaplermin topical:
Less common side effects
- rash or redness of the skin near the skin ulcer
Incidence not known
- burning sensation at the application site
- unusually warm skin
For healthcare professionals
Applies to becaplermin topical: topical gel.
Oncologic adverse events
- Common (1% to 10%): Cancer
- Postmarketing reports: Increased death rate from systemic malignancies[Ref]
Eight of 291 patients (2.7%) on this drug versus 2 of 200 placebo patients (1%) in 20 month clinical trial follow up studies developed cancer; types of cancer varied and all were remote from the treatment site.
Three retrospective postmarketing studies showed an increased death rate from systemic malignancies in patients who had used 3 or more tubes of becaplermin.[Ref]
Dermatologic
- Common (1% to 10%): Erythematous rash[Ref]
Local
References
1. (2001) "Product Information. Regranex (becaplermin topical)." Smith & Nephew, Inc.
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Further information
Regranex side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.