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Allanzyme Side Effects

Generic name: papain/urea topical

Note: This document contains side effect information about papain/urea topical. Some dosage forms listed on this page may not apply to the brand name Allanzyme.

Applies to papain/urea topical: topical foam, topical ointment, topical spray.


Skin irritation is rarely caused by the exudate resulting from the enzymatic digestion. More frequent dressing changes may alleviate this discomfort until the exudate decreases.[Ref]

Local side effects have rarely included a transient burning sensation and skin irritation.[Ref]


1. "Product Information. Accuzyme (papain-urea topical)." Healthpoint (2004):

2. "Product Information. Ethezyme (papain-urea topical)." Ethex Corporation (2005):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.