Medically reviewed by Drugs.com. Last updated on Jul 27, 2019.
(pol ee yoor EE a URE e thane)
- Poly Urea Urethane
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Nuvail™: 16% (15 mL)
Brand Names: U.S.
- Protectant, Topical
Biocompatible, polymeric solution; forms uniform film that protects nail from abrasion, friction, and moisture
Use: Labeled Indications
Nail dystrophy: Management of signs and symptoms of nail dystrophy such as nail splitting and nail fragility for intact or damaged nails.
Use with deep, open, or profusely bleeding wounds
Nail dystrophy: Topical: Apply once daily before bedtime to affected nail(s)
Refer to adult dosing.
Apply evenly to affected nail plate, proximal and lateral folds, and distal tip; allow to dry completely. Clean affected nails with nail polish remover once weekly. Use of other topical products before application of poly-ureaurethane may prevent film formation and reduce effectiveness. To avoid staining, avoid contact with finished surfaces (eg, furniture, counter tops).
Store at 15°C to 30°C (59°F to 86°F); avoid excessive heat and humidity. Flammable liquid; keep away from heat and flame; use in well-ventilated area.
There are no known significant interactions.
Frequency not defined: Dermatologic: Skin irritation, stinging of the skin
Concerns related to adverse effects:
• Skin irritation: May sting upon application; discontinue use if redness or other signs of irritation occur.
• Isocyanate sensitization: Patients sensitized to isocyanate should not use poly-ureaurethane.
• Flammable: Formulation is flammable; do not expose to high temperatures or near open flame. Use in a well-ventilated area.
• Discuss specific use of drug and side effects with patient as it relates to treatment. (HCAHPS: During this hospital stay, were you given any medicine that you had not taken before? Before giving you any new medicine, how often did hospital staff tell you what the medicine was for? How often did hospital staff describe possible side effects in a way you could understand?)
• Patient may experience stinging. Have patient report immediately to prescriber severe skin irritation.
• Educate patient about signs of a significant reaction (eg, wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat). Note: This is not a comprehensive list of all side effects. Patient should consult prescriber for additional questions.
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