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Poly-Ureaurethane

Medically reviewed by Drugs.com. Last updated on Jun 13, 2020.

Pronunciation

(pol ee yoor EE a URE e thane)

Index Terms

  • Poly Urea Urethane
  • Polyureaurethane

Dosage Forms

Excipient information presented when available (limited, particularly for generics); consult specific product labeling.

Solution, topical:

Nuvail™: 16% (15 mL)

Brand Names: U.S.

  • Nuvail™

Pharmacologic Category

  • Protectant, Topical

Pharmacology

Biocompatible, polymeric solution; forms uniform film that protects nail from abrasion, friction, and moisture

Use: Labeled Indications

Nail dystrophy: Management of signs and symptoms of nail dystrophy such as nail splitting and nail fragility for intact or damaged nails.

Contraindications

Use with deep, open, or profusely bleeding wounds

Dosing: Adult

Nail dystrophy: Topical: Apply once daily before bedtime to affected nail(s)

Dosing: Geriatric

Refer to adult dosing.

Administration

Apply evenly to affected nail plate, proximal and lateral folds, and distal tip; allow to dry completely. Clean affected nails with nail polish remover once weekly. Use of other topical products before application of poly-ureaurethane may prevent film formation and reduce effectiveness. To avoid staining, avoid contact with finished surfaces (eg, furniture, counter tops).

Storage

Store at 15°C to 30°C (59°F to 86°F); avoid excessive heat and humidity. Flammable liquid; keep away from heat and flame; use in well-ventilated area.

Drug Interactions

There are no known significant interactions.

Adverse Reactions

Frequency not defined: Dermatologic: Skin irritation, stinging of the skin

Warnings/Precautions

Concerns related to adverse effects:

• Skin irritation: May sting upon application; discontinue use if redness or other signs of irritation occur.

Special populations:

• Isocyanate sensitization: Patients sensitized to isocyanate should not use poly-ureaurethane.

Other warnings/precautions:

• Flammable: Formulation is flammable; do not expose to high temperatures or near open flame. Use in a well-ventilated area.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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