Medically reviewed by Drugs.com. Last updated on Jun 13, 2020.
(pol ee yoor EE a URE e thane)
- Poly Urea Urethane
Excipient information presented when available (limited, particularly for generics); consult specific product labeling.
Nuvail™: 16% (15 mL)
Brand Names: U.S.
- Protectant, Topical
Biocompatible, polymeric solution; forms uniform film that protects nail from abrasion, friction, and moisture
Use: Labeled Indications
Nail dystrophy: Management of signs and symptoms of nail dystrophy such as nail splitting and nail fragility for intact or damaged nails.
Use with deep, open, or profusely bleeding wounds
Nail dystrophy: Topical: Apply once daily before bedtime to affected nail(s)
Refer to adult dosing.
Apply evenly to affected nail plate, proximal and lateral folds, and distal tip; allow to dry completely. Clean affected nails with nail polish remover once weekly. Use of other topical products before application of poly-ureaurethane may prevent film formation and reduce effectiveness. To avoid staining, avoid contact with finished surfaces (eg, furniture, counter tops).
Store at 15°C to 30°C (59°F to 86°F); avoid excessive heat and humidity. Flammable liquid; keep away from heat and flame; use in well-ventilated area.
There are no known significant interactions.
Frequency not defined: Dermatologic: Skin irritation, stinging of the skin
Concerns related to adverse effects:
• Skin irritation: May sting upon application; discontinue use if redness or other signs of irritation occur.
• Isocyanate sensitization: Patients sensitized to isocyanate should not use poly-ureaurethane.
• Flammable: Formulation is flammable; do not expose to high temperatures or near open flame. Use in a well-ventilated area.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.