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Methylsulfonylmethane (MSM)

Medically reviewed by Last updated on Sep 28, 2020.

What are other common names?

  • Crystalline DMSO
  • Dimethyl Sulfone MSM
  • Dimethylsulfone
  • Diméthylsulfone
  • DMSO2
  • Methyl Sulfone
  • Methyl Sulfonyl Methane
  • Methyl Sulphonyl Methane
  • Methylsulfonylmethane
  • Metilsulfonilmentano
  • MSM
  • Méthyle Sulfonyle Méthane
  • Méthyle Sulphonyle Méthane
  • Méthylsulfonylméthane
  • Sulfone de Diméthyle MSM
  • Sulfone de Méthyle
  • Sulfonyl Sulfur

What is this product used for?

Methylsulfonylmethane is also called MSM. It is used by some people to help with pain, especially from arthritis. Others use it to help with an upset stomach or decrease muscle damage caused by exercise. Some people believe it helps to boost the immune system, fight infections, or help with allergies. It may also be used by some people to help fight skin conditions or hemorrhoids.

What are the precautions when taking this product?

  • Always check with your doctor before you use a natural product. Some products may not mix well with drugs or other natural products.

  • Do not use this if you are pregnant or plan to become pregnant soon. Use birth control you can trust while taking this product.

  • Do not use this product if you are breastfeeding.

What should I watch for?

  • Upset stomach

  • Bloating or indigestion

  • Constipation

  • Tiredness

  • Problems sleeping

  • Problems concentrating

  • Itching or worsening of allergy stymptoms

When do I need to call the doctor?

  • Signs of a very bad reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat. Go to the ER right away.

  • Very bad throwing up

  • Very bad loose stools

  • Very bad headache

Last Reviewed Date


Consumer information use

This information is not specific medical advice and does not replace information you receive from your healthcare provider. Only your healthcare provider has the knowledge and training to provide advice that is right for you. You should not rely on this information in deciding whether or not to use, or accept your healthcare provider’s advice regarding use of, any natural products or similar treatments, therapies, or life-style choices. This information does not endorse any natural products or similar treatments, therapies, or life-style choices as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information. It does NOT include all information about natural products, possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to you. You must talk with your healthcare provider for complete information about your health and treatment options.


Copyright © 2018 Wolters Kluwer Clinical Drug Information, Inc. and its affiliates and/or licensors. All rights reserved.

Further information

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