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Medically reviewed by Last updated on Feb 5, 2021.

What are other common names?

  • Androstenolone
  • Dehydroepiandrosterone Sulfate
  • DHEA
  • DHEA-S
  • GL701
  • Prasterone

What is this product used for?

Dehydroepiandrosterone is a hormone and is also called DHEA. It is used by some people to help with low mood. Some older women may use DHEA applied inside the vagina to decrease pain during sex. Others may use is to improve skin problems related to aging.

What are the precautions when taking this product?

  • Always check with your doctor before you use a natural product. Some products may not mix well with drugs or other natural products.

  • This product may interfere with some lab tests. Be sure to talk with your doctor about this and all drugs you are taking.

  • Do not use this product if you are pregnant or plan to become pregnant soon. Use birth control you can trust while taking this product.

  • Do not use this product if you are breastfeeding.

  • Do not use this product if you have health problems that are sensitive to hormones. These are problems like breast cancer, prostate cancer, or endometriosis.

  • Take extra care if you are taking drugs that affect your hormones. These are drugs like estrogen, progesterone, testosterone, anastrozole (Arimidex), exemestane (Aromasin), fluvestrant (Faslodex), letrozole (Femara), or tamoxifen (Nolvadex).

  • Take extra care if you are taking drugs to thin your blood. These are drugs like warfarin (Coumadin), heparin, or enoxaparin (Lovenox).

  • Take extra care if you are taking drugs to dissolve blood clots. These are drugs like alteplase (Activase), reteplase (Retevase), or streptokinase (Streptase).

  • Take extra care if you are taking drugs to help with swelling or inflammation that can also increase your risk of bleeding. These are drugs like nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, ibuprofen (Advil), or naproxen (Naprosyn or Aleve).

  • Take extra care if you are scheduled to receive the vaccine for tuberculosis. This product can make the vaccine less effective.

  • Take extra care and check with your doctor if you have:

    • Kidney problems

    • Liver problems

    • Problems with your uterus or ovaries

    • High blood pressure

    • Cholesterol problems

    • Diabetes

    • Cancer, especially breast or prostate cancer

    • Low mood or other mood disorders

    • Mental health problems

  • Keep hard candies, glucose tablets, liquid glucose, or juice on hand for low blood sugar.

What should I watch for?

  • Upset stomach

  • Acne

  • Hair growth or hair loss

  • High blood pressure

  • Mood changes like feeling irritable or aggressive

  • Problems sleeping

  • Enlarged breasts in men or women

  • For men: Testes problems

  • For women:

    • Change in menstrual cycle

    • Voice gets deeper

    • Hair growth on face

When do I need to call the doctor?

  • Signs of a very bad reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat. Go to the ER right away.

  • Signs of high blood pressure. These include very bad headache, nervousness, problems breathing, or nosebleeds.

  • Signs of low blood sugar. These include hunger, dizziness, shaking, a fast heartbeat, confusion, or sweating.

  • Very bad throwing up

  • Very bad loose stools

  • Signs of liver problems like upset stomach or throwing up, belly pain, feeling tired, dark urine, yellow skin or eyes, not hungry

Last Reviewed Date


Consumer information use

This information is not specific medical advice and does not replace information you receive from your healthcare provider. Only your healthcare provider has the knowledge and training to provide advice that is right for you. You should not rely on this information in deciding whether or not to use, or accept your healthcare provider’s advice regarding use of, any natural products or similar treatments, therapies, or life-style choices. This information does not endorse any natural products or similar treatments, therapies, or life-style choices as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information. It does NOT include all information about natural products, possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to you. You must talk with your healthcare provider for complete information about your health and treatment options.


Further information

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