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Leader Lice Solution

Generic name: piperonyl butoxide and pyrethrins topicalpye-PER-oh-nil-bue-TOX-ide-and-pye-REE-thrins-TOP-i-kal ]
Brand names: A-200 Lice Treatment, Good Sense Lice Killing Shampoo, Step 1, Pronto Lice Kill System, R and C Lice Treatment Kit, ... show all 17 brands

Medically reviewed by Drugs.com on Aug 3, 2023. Written by Cerner Multum.

What is Leader Lice Solution?

Piperonyl butoxide is a chemical that stops the breakdown of pyrethrins, an insecticide chemical.

Leader Lice Solution (for the skin) is a combination medicine used to treat lice.

Leader Lice Solution may also be used for purposes not listed in this medication guide.

Leader Lice Solution side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using piperonyl butoxide and pyrethrins and call your doctor at once if you have severe stinging, burning, itching, swelling, or irritation where the medication is applied.

Common side effects of Leader Lice Solution may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before taking this medicine

You should not use Leader Lice Solution if you are allergic to it, or if you have an allergy to chrysanthemums or ragweed.

FDA pregnancy category C. It is not known whether Leader Lice Solution will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I use Leader Lice Solution?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Lice infestations are highly contagious. All household members may need to be treated for lice. Lice can be spread from person to person by sharing a hairbrush, a comb, hats, or headbands. It can also be spread through head-to-head contact.

Apply the shampoo to dry hair. Shake well before use. Apply to all areas of the scalp, including behind the ears and neck. Treat hair from the roots to the ends and leave the shampoo in the hair for no longer than 10 minutes, then rinse thoroughly with warm water. The shampoo should be used again in 7 to 10 days to kill any newly hatched lice.

Keep your eyes tightly closed while using this medicine in your hair. You may use a washcloth or towel to protect your eyes while applying the medication to your head. Do not apply to your eyebrows or eyelashes. Call your doctor if these areas become infected with lice.

You will need to remove any eggs (nits) from the hair shafts with a special comb. Some lice products come provided with a nit comb. If you do not have such a comb, ask your pharmacist where you can get one. Nits may not be removed effectively with a regular fine-tooth comb.

Use this medication for the full prescribed length of time. Your symptoms may improve before the lice infestation is completely cleared. Call your doctor if your condition does not improve, or if your symptoms get worse while using this medication.

To prevent reinfection with lice, wash all clothing, hats, bed linens, stuffed toys, hair brushes, and combs in hot water with a strong cleanser to remove any mites or eggs. You may need to use a special lice control spray to treat furniture, mattresses, sports helmets, headphones, and other non-washable items. Ask your doctor or pharmacist about disinfecting your home.

Store the medicine at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Leader Lice Solution?

Avoid using other medications or skin products on the areas you treat with Leader Lice Solution, unless your doctor tells you to.

Avoid getting this medication in your eyes, nose, mouth, or vagina. If this does happen, rinse with water. Do not use Leader Lice Solution on sunburned, windburned, dry, chapped, irritated, or broken skin.

Avoid close contact with others until the infection has been cured. Also avoid sharing hair combs, hair accessories, hats, clothing, bed linens, pillows, and other items of personal use.

What other drugs will affect Leader Lice Solution?

It is not likely that other drugs you take orally or inject will have an effect on topically applied piperonyl butoxide and pyrethrins. But many drugs can interact with each other. Tell each of your health care providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

More about Leader Lice Solution (piperonyl butoxide / pyrethrins topical)

Patient resources

Other brands

Licide, RID, A-200 Lice Treatment, Good Sense Lice Killing Shampoo, Step 1, ... +6 more

Professional resources

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.