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How does Vistogard work?

Medically reviewed by Drugs.com Last updated on Apr 12, 2019.

Official Answer

by Drugs.com

Vistogard (uridine triacetate) works by slowing down cell damage caused by certain cancer medicines (fluorouracil or capecitabine). It is a metabolite of fluorouracil, FUTP, which blocks DNA replication and repair. Uridine, from uridine triacetate, competitively inhibits cell damage and cell death caused by fluorouracil.

It is the emergency treatment of adult and pediatric patients following an overdose of the chemotherapy agents 5-fluorouracil (5-FU) or capecitabine. 

It is not known if Vistogard is safe and effective if started more than 4 days (96 hours) after the end of a dose of fluorouracil or capecitabine.

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