Tibolone

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

G03CX01,G03DC05

CAS registry number (Chemical Abstracts Service)

0005630-53-5

Chemical Formula

C21-H28-O2

Molecular Weight

312

Therapeutic Categories

Hormone replacement therapy (HRT)

Synthetic steroid with partial estrogenic, progestagenic and androgenic activity

Chemical Name

19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-7-metyl-, (7α,17α)-

Foreign Names

• Tibolonum (Latin)
• Tibolon (German)
• Tibolone (French)
• Tibolona (Spanish)

Generic Names

• Tibolone (OS: USAN, DCF, BAN, JAN)
• Org OD 14 (IS)
• Tibolone (PH: BP 2018, Ph. Eur. 9)
• Tibolonum (PH: Ph. Eur. 9)

Brand Names

• Amena
  BioFemme, Philippines
• Analobit
  Hispanoameric, Mexico
• Boltin
  Merck Sharp & Dohme, Spain
• Bontil
  Probiomed, Mexico
• Climabel 2.5mg
  Chemo Iberica S.A., Vietnam
• Climafen
  ABL, Ecuador; Laboratorios Andromaco, Chile
• Climatix
  Investi, Argentina
• Clindella
  Nova Química Farmacêutica, Brazil
• Clitax
  Tecnimede, Portugal
• Discretal
  Beta, Argentina
• Evatibol
  Eticos, Paraguay
• Femsel
  Elmor, Venezuela
• Fomene
  Leti, Venezuela
• Goldar
  Pentafarma, Portugal
• Heria
  Mithra, Belgium
• Heria 2.5mg
  Mithra, Luxembourg
• Klimastress
  Craveri, Argentina
• Ladybon
  Zentiva, Czech Republic; Zentiva, Lithuania; Zentiva, Poland; Zentiva, Russian Federation; Zentiva, Slovakia
• Ladybon 2.5 mg
  Q Pharma, Hungary
• Libron
  Myungmoon, South Korea
• Lirex
  Laboratorios Silesia, Chile; Silesia, Paraguay
• Livial
  BB Farma, France; Beximco, Bangladesh; Farmagon, Norway; Laboratorio Saval, Chile; M.S.D., Portugal; Mediwin, France; Merck, Brazil; Merck KgaA, Greece; Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, United Kingdom; Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Indonesia; Merck Sharp & Dohme, Malta; Merck Sharp & Dohme, Mexico; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, New Zealand; Merck Sharp & Dohme, Philippines; Merck Sharp & Dohme, Romania; Merck Sharp & Dohme BV, Iceland; MSD, Costa Rica; MSD, Denmark; MSD, Dominican Republic; MSD, Finland; MSD, France; MSD, Guatemala; MSD, Honduras; MSD, Ireland; MSD, Nicaragua; MSD, Norway; MSD, Panama; MSD, Peru; MSD, Sweden; MSD, El Salvador; MSD, Thailand; MSD Belgium, Belgium; MSD Merck Sharp & Dohme, Turkey; N V Organon, Cyprus; Organon, Bulgaria; Organon, Bahrain; Organon, Czech Republic; Organon, Egypt; Organon, India; Organon, Kuwait; Organon, Lebanon; Organon, Lithuania; Organon, Latvia; Organon, Netherlands; Organon, Oman; Organon, Pakistan; Organon, Poland; Organon, Slovakia; Organon, Venezuela; Organon Ireland, Serbia; Organon Italia, Italy; Schering-Plough, Ecuador; Schering-Plough, Taiwan
• Livial (Merck Sharp & Dohme
  China MSD, China
• Livial
  Merck Sharp & Dohme Pharma Singapore, Singapore
• Livial 2.5mg
  MSD, Switzerland; MSD Belgium, Luxembourg; MSD Pharma, Hungary; Organon, Israel
• Livial-3
  Merck, Brazil
• Liviel
  Organon, Austria
• Liviella
  MSD Merck Sharp & Dohme, Germany
• Livifem
  Merck, South Africa
• Livolon
  Biolab Sanus Farmacêutica, Brazil
• Lobion-Hrt
  Platinum, Pakistan
• Marysa 2.5mg
  Gedeon Richter Schweiz, Switzerland
• Menorest
  Medispec, Malaysia; Renata, Bangladesh
• Menotrix
  Medicamenta Ecuatoriana, Ecuador
• Menox
  Roddome, Ecuador
• Paraclim
  Elea, Argentina; Urufarma, Uruguay
• Paraclim 1.25
  Elea, Argentina
• Qi Luo Shu
  Yo Hua Pharm, China
• Reduclim
  Farmoquimica FQM, Brazil
• Renorma
  Square, Bangladesh
• Sintemel
  Asofarma de Mexico, Mexico
• Tibaclim [+ Calcium Carbonate, + Colecalciferol]
  Rimsa, Mexico
• Tibelia
  Campus Pharma, Finland; Campus Pharma, Sweden
• Tibial
  Neo Química, Brazil
• Tibicare
  Procare Health, Spain
• Tibocina
  Sandoz, Denmark; Sandoz, Italy; Sandoz, Sweden; Sandoz España, Spain
• Tiboclim
  Panalab, Argentina
• Tiboclin
  EMS, Brazil
• Tibofem
  MSD Argentina, Argentina
• Tibolinia
  Sandoz, Belgium; Sandoz, Netherlands
• Tibolon
  N.V. Organon, Netherlands
• Tibolon Aristo
  Aristo Pharma, Germany
• Tibolon Mithra
  Mithra, Netherlands
• Tibolon Mylan
  Mylan, Netherlands; Mylan, Sweden
• Tibolon Orifarm
  Orifarm Generics, Denmark; Orifarm Generics, Iceland; Orifarm Generics, Sweden
• Tibolon Sandoz 2.5mg
  Sandoz, Switzerland
• Tibolona
  Amsa, Mexico; Genamerica, Ecuador
• Tibolona Aristo
  Aristo, Spain
• Tibolona EMS
  EMS, Brazil
• Tibolona Gen. Germed
  Genéric.Germed, Brazil
• Tibolona Gen. Legrand
  Genéric.Legrand, Brazil
• Tibolona Neo Quimica
  Neo Química, Brazil
• Tibolona Nova Quimica
  Nova Química Farmacêutica, Brazil
• Tibolona Servimedic
  Servimedic, Uruguay
• Tibolona Zentiva
  Sanofi-Aventis, Portugal
• Tibolone
  Aristo, United Kingdom; Concordia, United Kingdom; Generic Partners UK, United Kingdom
• Tibolone - Zizhu
  Zizhu, China
• Tibolone Adwia
  Adwia, Egypt
• Tibolone Teva
  Teva, Lithuania
• Tibolone-Mithra 2.5mg
  Mithra, Luxembourg
• Tibolon-Mepha 2.5mg
  Mepha Pharma, Switzerland
• Tibolux
  Hospimedikka, Ecuador
• Tibomax
  Sherfarma, Peru
• Tibona
  ABL Pharma, Peru; Celsius, Uruguay
• Tibone
  Techno Drugs, Bangladesh
• Tibonella
  Laboratorios Chalver, Ecuador
• Tibonor
  Eskayef, Bangladesh
• Tilia
  Aristo, Spain
• Tilogran
  Legrand/Tarja, Brazil
• Tiloria 2.5mg
  Aristo Pharma, Austria
• Tinox
  Abbott, Colombia; Gynopharm, Chile; Gynopharm, Peru; Recalcine, Paraguay; Vivax, Venezuela
• Tivion
  ACI, Bangladesh
• Tobe
  Chile S.A., Paraguay; Laboratorio Chile, Chile
• Tocline
  Rontag, Argentina
• Ubilon
  Incepta, Bangladesh
• Xyvion
  Merck Sharp & Dohme, Australia

Glossary

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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