Skip to Content


Maria Sharapova, former world number one tennis player, failed a drug test for Meldonium on January 26, 2016. Meldonium (also known as Mildronate) is manufactured in Latvia and used in the treatment of certain heart conditions. It works by dilating blood vessels and increasing blood flow, which in turn improves exercise capacity, physical and mental endurance, and also brain function.

Meldonium was on the World Anti-Doping Agency’s (WADA) list of drugs being monitored until September 2015, when it was added to the list of banned substances, effective January 1, 2016.

Maria Sharapova had been taking Meldonium since 2006. Her family doctor had prescribed it for her irregular EKGs, magnesium deficiency, and a family history of diabetes. Sharapova claims she was unaware Meldonium had been added to the WADA list of banned substances until receipt of a letter from the International Tennis Federation informing her of a failed drug test during the 2016 Australian Open.



CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Treatment of cardiac disorders

Inhibitor of carnitine synthesis

Chemical Names

3-(2,2,2-Trimetyldiazaniumyl)propanoate (WHO)

3-(2,2,2-Trimetylhydrazinium)propionat (IUPAC)

Foreign Names

  • Meldonium (Latin)
  • Meldonium (German)
  • Meldonium (French)
  • Meldonio (Spanish)

Generic Names

  • Mildronate (IS)
  • Meldonium Dihydrate (PH: BP 2018, Ph. Eur. 9)

Brand Names


IUPACInternational Union of Pure and Applied Chemistry
ISInofficial Synonym
PHPharmacopoeia Name
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.