Ketotifen (International)

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

R06AX17,S01GX08

CAS registry number (Chemical Abstracts Service)

0034580-13-7

Chemical Formula

C19-H19-N-O-S

Molecular Weight

309

Therapeutic Categories

Antiallergic agent

Histamine H₁-receptor antagonist (H₁-antihistaminic)

Chemical Name

10H-Benzo[4,5]cyclohepta[1,2-b]tiophen-10-one, 4,9-dihydro-4-(1-metyl-4-piperidinylidene)-

Foreign Names

• Ketotifenum (Latin)
• Ketotifen (German)
• Kétotifène (French)
• Ketotifeno (Spanish)

Generic Names

• Ketotifen (OS: BAN)
• Ketotifene (OS: DCIT)
• Kétotifène (OS: DCF)
• Ketotifen Fumarate (OS: USAN, JAN, BANM)
• HC 20 511 nfu (IS)
• HC 20-511 (IS)
• Ketotifenhydrogenfumarat (IS)
• Ketotifen Fumarate (PH: BP 2018, JP XVII)
• Ketotifen hydrogen fumarate (PH: Ph. Eur. 9)
• Ketotifeni hydrogenofumaras (PH: Ph. Eur. 9)

Brand Names

• Airyfen
  Panacea, India
• Aktofen
  Alliance, Pakistan
• Albalon
  Allergan, India
• Allerban
  Apex, Egypt
• Antifen
  Pharmix, Pakistan
• Aria
  Highnoon, Pakistan
• Asdown
  Shun Sheng, Taiwan
• Asfen
  Remington, Pakistan
• Asmafen
  Xepa-Soul Pattinson, Malaysia
• Asmaral K
  Serral, Mexico
• Asmarax
  Mediceena, Pakistan
• Asmindin
  Ciiphar, Taiwan
• Asmofen
  Medicaids, Pakistan
• Asperfin
  Davis, Pakistan
• Astaf 5 ml 1 mg
  Sandoz, Turkey
• Asthacure
  Medicraft, Pakistan
• Asthafen
  Torrent, India
• Asthanil
  Siza, Pakistan
• Asthonex
  Medera, Pakistan
• Asthotifen
  Zafa, Pakistan
• Asumalife
  Yung Shin, Taiwan
• Athmin
  Center, Taiwan
• Biotifen
  Bioresearch, Mexico
• Bronclear
  Neomedix, Pakistan
• Bronquiasmol
  Eticos, Paraguay
• Cleroptic
  Cooper, Malta
• Cosolve
  Vargas, Venezuela
• Daesma
  Raka Poshi, Pakistan
• Detofen
  Deva, Turkey
• Dhatifen
  DHA, Malaysia; DHA, Singapore
• Fumast
  Rasyonel, Turkey
• Galitifen
  Galenika AD, Serbia
• Histofen
  Riyadh Pharma, Oman
• Katifen
  General Drugs House, Thailand; Yu Sheng, Taiwan
• Kedrop
  ASG Medical, Peru
• Keften
  Helicon, Pakistan
• Kenaler
  Ophtha, Peru
• Kenerlin
  Sinton, Taiwan
• Ketane
  Athena, Uruguay
• Keten
  Siam Bheasach, Thailand
• Ketin
  Opalia, Tunisia
• Ketofen
  Health Chemical, Taiwan; Hor Chen, Taiwan; Newai Chem, Taiwan
• Ketoftil
  Farmigea, Lebanon
• Ketoftil 0.05%
  Farmigea, Malta
• Ketonal
  Pharma Investi, Uruguay; Roemmers, Ecuador
• Ketonil 1mg
  Ram Pharmaceutical, Oman
• Ketonil 1mg/5ml
  Ram Pharmaceutical, Oman
• Ketoti
  Pharco, Egypt; Yung Chi, Taiwan
• Ketotif
  Kopran, India
• Ketotifen
  BCPP, Georgia; Experimental Plant GNCLS, Georgia; Lekhim, Georgia; Pharma Investi, Uruguay; Rue Belmedpreparaty, Georgia
• Ketotifen Actavis
  Actavis, Lithuania
• Ketotifen Bipharma
  Bipharma, Netherlands
• Ketotifen Laropharm
  Laropharm, Romania
• Ketotifen Magistra
  Magistra, Romania
• Ketotifen Sopharma
  Sopharma, Latvia
• Ketotifen Stulln UD
  Pharma Stulln, Serbia
• Ketotifen WZF Polfa
  Warszawskie Zaklady Farmaceutyczne Polfa, Lithuania
• Ketotifeno
  Best, Mexico; Bioresearch, Mexico; Kener, Mexico; Recipe, Colombia; Serral, Mexico
• Ketotifeno Catedral
  Catedral, Paraguay
• Ketotifeno Ecar
  Ecar, Colombia; Ecar, Ecuador
• Ketotifeno Fmndtria
  Farmindustria, Peru
• Ketotifeno Genfar
  Genfar, Ecuador; Genfar, Peru; Genfar S.A., Costa Rica; Genfar S.A., Dominican Republic; Genfar S.A., Honduras; Genfar S.A., Nicaragua; Genfar S.A., El Salvador
• Ketotifeno ion
  Ion, Uruguay
• Ketotifeno MK
  MK, Colombia; MK, Ecuador
• Ketotisin
  Chemopharma, Chile; Dollder, Venezuela
• Ketovis
  Pharma Stulln, Spain
• Ketozad
  Dosaco, Pakistan
• Ketozen
  Shinlon, Taiwan
• Kotin
  Schazoo, Pakistan
• Leket
  Laema Chemi Pharma, Pakistan
• Licoften 1mg
  Remedica, Oman
• Mactifen
  Macter, Pakistan
• Maktofen
  Makson, Pakistan
• Mamicon
  Patron, Taiwan
• Mastifen
  East West, India
• Mastifen-C [+ Cetirizine]
  East West, India
• Mastifen-S [+ Salbutamol]
  East West, India
• Mastosytex 0.025%
  Sigmatec, Egypt
• Miradil
  Lafedar, Argentina
• Mitofen
  Münir Sahin, Turkey
• Ocutif
  Asiatic Lab, Bangladesh
• Oftaler
  Nicolich, Chile; Saval, Ecuador
• Oftaler Colirio
  Saval, Paraguay
• Oftaler Forte
  Saval, Peru
• Orchazid 0.025%
  Orchidia, Egypt
• Osaten
  Offenbach, Mexico
• Prophallerge
  Rameda, Egypt
• Rednott 0.025%
  Pharaonia, Egypt
• Sanketo
  Novartis, Bangladesh
• Soother
  CCPC, Taiwan
• Tefanyl
  Saiph, Tunisia; Simed, Tunisia
• Tong Fen
  Baotou, China
• Totifen
  Patron, Taiwan; Renata, Bangladesh
• Tranlen
  Lotus Pharmaceuticals, Taiwan
• Tritofen
  FDC, India
• Uniteno
  Roster, Peru
• Venti-Bron
  Imfar, Paraguay
• Zabak
  Laboratoires Thea, Poland
• Zadifen
  Unimed & Unihealth, Bangladesh
• Zaditen
  Al Pharm, South Africa; Alcon, Peru; Laboratoires Thea, Slovenia; Novartis, Egypt; Novartis, Mexico; Novartis, Poland; Novartis, Taiwan; Thea, Turkey
• Zaditen 0.025%
  Novartis, Egypt
• Zaditen 0.50 mg/ml
  THEA, Hungary
• Zaditen-SRO
  Novartis, Turkey
• Zalerg
  Thea, Tunisia
• Zasiten Ofta
  Thea, Mexico
• Zasten
  Alfasigma España, Spain
• Zatizen
  Shou Chan, Taiwan
• Zedotefen
  Adwic, Egypt
• Zetiffen
  Zydus Cadila, India
• Zetofen
  T.O. Chemicals, Thailand
• Zylofen
  Memphis Co., Egypt
• Adco-Zetofen
  Al Pharm, South Africa
• Aerofen
  Silva Pharmaceuticals, Bangladesh
• Alarid
  Square, Bangladesh
• Alaway
  Bausch & Lomb, United States
• Alercorn
  Hanmi, South Korea
• Allergo-Vision 0,25mg/ml
  OmniVision, Germany
• Allerket
  Pulitzer, Italy
• Altriabak
  Laboratoires Théa, Belgium; Laboratoires Théa, Netherlands
• Altriabak-0.25mg/ml
  Laboratoires Thea, Luxembourg
• Amitone [pediatric]
  Unison, Hong Kong
• Antilerg
  Max Visión, Argentina
• Asmafen
  Xepa-Soul Pattinson, Hong Kong
• Asmafort
  Julphar, Kuwait; Julphar, Oman
• Asmafort 1mg
  Julphar, Oman
• Asmanon Xarope
  Cazi Quimica Farmaceutica Industria e Comercio, Brazil
• Asmofen
  Teuto Brasileiro, Brazil
• Asthan
  Pei Li, Taiwan
• Astifen
  Christo, Hong Kong; Taiwan Veterans, Taiwan
• Astofen
  Washington, Taiwan
• Asumalife
  YSP Industries, Thailand
• Axcel Ketotifen
  Kotra Pharma, Hong Kong
• Azimef
  YSP, Philippines
• Bei Ka Ming
  Kexing Biotech, China
• Benanza 0.05%
  Koa Isei, Japan
• Bentifen
  Laboratoires Théa, Sweden; Novartis Farma, Italy; Thea, Spain
• Blasket
  Blaskov, Colombia
• Broket
  Orion, Bangladesh
• Chetofen
  Boniscontro & Gazzone, Italy
• Chetotifene Mylan Generics
  Mylan, Italy
• Chin Ni Chuan
  Jen Sheng, Taiwan
• Citol Aler
  Oftalmica, Paraguay
• Cleroptic
  Cooper, Greece
• Cleroptic 0.025%
  Cooper, Greece
• Cofen
  Chen Ho, Taiwan
• Deantran
  Root, Taiwan
• Defen
  Purzer, Taiwan
• Denerel
  Medochemie, Lithuania; Medochemie, Slovakia; Medochemie, Taiwan; Medochemie Singapore, Singapore
• Dhatifen
  DHA, Hong Kong
• Dilabron
  Elifarma, Paraguay
• Dovidin
  Anfarm, Greece
• Dovidin 0.025%
  Anfarm, Greece
• Edifen
  Daewoo, South Korea
• Eytofen
  Kobec, Pakistan
• Farmoftal
  HLB Pharma Group Chile, Chile
• Fenat
  Drug International, Bangladesh
• Frenaler
  Pharma Investi, Paraguay
• Fumarato de Cetotifeno
  Biosintética, Brazil; EMS, Brazil; Genéric.Germed, Brazil; Genéric.Legrand, Brazil; Medley, Brazil; Neo Química, Brazil; Prati, Donaduzzi, Brazil; Teuto Brasileiro, Brazil; União Química, Brazil
• Fumarton 0.05%
  Nitten Pharmaceutical, Japan
• Fusachol 0.05%
  Medisa Shinyaku, Japan
• Galitifen
  Galenika, Bosnia & Herzegowina
• Gloditen
  Global Pharma, Oman
• Gloditen 1mg/5ml
  Global Pharma, Oman
• Histofen
  Medical & Cosmetic, Kuwait
• Hyalcrom NF
  arcos, Uruguay; Bausch & Lomb, Argentina
• Intifen
  Interbat, Indonesia
• Kasmal
  Silanes, Mexico
• K-Drops
  Exelixis, Greece
• Kedrop
  Grin, Mexico
• Kefen
  Hua Shin, Taiwan
• Keraffler
  Loeffler, Mexico
• Ketasma
  Sun, India; Sun, Lithuania
• Ketibron
  Weidar, Taiwan
• Ketifen
  Acme, Bangladesh; Hwang's, Taiwan
• Ketimin
  Yuan Chou, Taiwan
• Ketodil
  Techno Drugs, Bangladesh
• Ketof
  Hexal, Czech Republic; Hexal, Germany; Hexal, Romania; IBN, Myanmar; Ibn Sina, Bangladesh
• Ketofex
  Dermapharm, Germany
• Ketoftal
  MK, Colombia
• Ketoftil
  Farmigea, Italy; Farmigea, Lebanon
• Ketomar
  Incepta, Bangladesh
• Ketomed
  Ramos, Nicaragua
• Ketomin
  Everest, Taiwan
• Ketoptic
  Oftalmi, Venezuela
• Ketosan
  Hasan-Dermapharma, Vietnam
• Ketosan-Cap
  Hasan-Dermapharma, Vietnam
• Ketosma
  Kojar, Taiwan
• Ketot
  Schazoo, Pakistan
• Ketotif
  Delta, Bangladesh
• Ketotifen
  Astar, Taiwan; Aztec, Georgia; Chin Teng Pharmaceutical Industrial, Taiwan; GMP, Georgia; Help, Greece; Nichi-Iko Pharmaceutical, Japan; Pfoshen, Taiwan; Polpharma, Georgia; Sawai Seiyaku, Japan; Siu Guan, Taiwan; Sopharma, Georgia; Takeda Teva Pharma, Japan; Tatsumi Kagaku, Japan; Yoshindo, Japan
• Ketotifen 0.02%
  Nichi-Iko Pharmaceutical, Japan; Takeda Teva Pharma, Japan; Tatsumi Kagaku, Japan
• Ketotifen 0.05%
  Choseido Pharmaceutical, Japan; Mylan Seiyaku, Japan; Nichi-Iko Pharmaceutical, Japan; Nisshin Pharmaceutical, Japan; Sawai Seiyaku, Japan; Takeda Teva Pharma, Japan; Toa Yakuhin, Japan
• Ketotifen 0.1%
  Nichi-Iko Pharmaceutical, Japan; Sawai Seiyaku, Japan; Takeda Teva Pharma, Japan; Tatsumi Kagaku, Japan
• Ketotifen Actavis
  Balkanpharma-Trojan, Bulgaria
• Ketotifen AL
  Aliud, Czech Republic
• Ketotifen Apotex
  Apotex Nederland, Netherlands
• Ketotifen Fumarate
  Akorn Animal Health, United States; Alcon, United States; Apotex, United States; Sannova, Japan
• Ketotifen Fumarate - Novartis
  Beijing Novartis Pharma Co., Ltd., China
• Ketotifen Fumarate-Beida Pharm
  Beida, China
• Ketotifen Fumarate-Fudan Fuhua Pharm
  Fudan Fuhua, China
• Ketotifen Hasco
  Hasco-Lek, Poland
• Ketotifen LPH
  Labormed Pharma, Romania
• Ketotifen PF 0.05%
  Nippon Tenganyaku Kenkyujo, Japan
• Ketotifen Ratiopharm
  Ratiopharm, Lithuania
• Ketotifen Sopharma 0.2mg/ml
  Sopharma, Bulgaria
• Ketotifen Sopharma 1mg
  Sopharma, Bulgaria
• Ketotifen Stada
  Stada, Lithuania
• Ketotifen STADA
  Stada Arzneimittel, Germany
• Ketotifen SteriMax
  SteriMax, Canada
• Ketotifen Stulln
  Pharma Stulln, Germany; Pharma Stulln, Netherlands
• Ketotifen Stulln 250 μg/ml
  Pharma Stulln, Austria
• Ketotifen Teva
  Teva Nederland, Netherlands; Teva Pharma Belgium, Belgium
• Ketotifen WZF
  Polfa Warszawa, Poland
• Ketotifen WZF Polfa
  WZF Polfa, Slovakia
• Kétotifène Thea
  Laboratoires Théa, France
• Ketotifeno Dutriec
  Dutriec, Paraguay
• Ketotifeno Farmalider
  Farmalider, Spain
• Ketoxdelt
  Delta, Colombia
• Klevistamin
  Kleva, Lithuania
• Kofen
  Opsonin, Bangladesh
• Licoften
  Remedica, Bahrain; Remedica, Cyprus
• Lidina
  Edol, Georgia; Edol, Portugal
• Magotiphen
  Tsuruhara Seiyaku Pharmaceutical, Japan
• Magotiphen 0.05%
  Tsuruhara Seiyaku Pharmaceutical, Japan
• Magotiphen 0.1%
  Tsuruhara Seiyaku Pharmaceutical, Japan
• Meni
  Pharmex, Greece
• Meni 0.025%
  Pharmex, Greece
• Meni-Drops
  Pharmex, Cyprus
• Minia
  Novo Healthcare, Bangladesh
• Monokéto
  Horus, France
• Montof
  Aversi, Georgia
• Nomotec-S
  Tecnofarma, Mexico
• Noxtor
  Rafarm, Greece
• Octifen
  União Química, Brazil
• Okeye
  Mabo, Spain
• Profilar 1mg/5ml
  United Pharmaceutical, Oman
• Profilas
  Kalbe, Indonesia
• Profiten
  Perrigo, Israel
• Prosma
  ACI, Bangladesh
• Respimex
  Pfizer, Argentina; Pharmacia Arg., Paraguay
• Rui Na Ti
  Shandong Lv Yin Pharmaceutical Co., Ltd, China
• Santiten
  Shyh Dar, Taiwan
• Scanditen
  Tempo Scan Pacific, Indonesia
• Sekiton 0.02%
  Kyorin Rimedio, Japan
• Sekiton 0.05%
  Kyorin Rimedio, Japan
• Sekiton 0.055%
  Kyorin Rimedio, Japan
• Sosefen
  So.Se. Pharm, Italy; Special Product's Line, Georgia
• Stafen
  Aristopharma, Bangladesh
• Supdel
  Towa Yakuhin, Japan
• Supdel 0.02%
  Towa Yakuhin, Japan
• Supdel 0.05%
  Towa Yakuhin, Japan
• Supdel 0.1%
  Towa Yakuhin, Japan
• Syntifen
  Synmosa, Taiwan
• Tenerel
  Medochemie, Cyprus
• Tofen
  Beximco, Bangladesh
• Toma
  Navana, Bangladesh
• Tosma
  Sanbe, Indonesia
• Toti
  Eskayef, Bangladesh
• Uprem
  Zwitter Pharmaceuticals, Cyprus
• Urpem
  Zwitter Pharmaceuticals, Greece
• Ventirene
  Celsius, Paraguay; Celsius, Uruguay
• Ventisol
  Teva, Mexico
• Wasserket
  MK, Colombia
• Xu Hong [+ Theophylline]
  Di Ao Pharmaceutical Group, China
• Zabak
  Lab. Thea, Romania
• Zabak 0.25mg/ml
  Théa Pharma, Switzerland
• Zadec
  Novartis Healthcare, Philippines
• Zadec SRO
  Novartis Healthcare, Philippines
• Zaditen
  Alcon, Colombia; Alcon, Hong Kong; Alcon, Thailand; Alfasigma France, France; Alfasigma S.p.A, Netherlands; Defiante, Italy; Defiante, Italy; Eureco-Pharma, Netherlands; Excelvision, Israel; Gramón Bagó, Uruguay; Lab. Thea, Romania; Laboratoires Thea, Cyprus; Laboratoires Thea, Iceland; Laboratoires Thea, Poland; Laboratoires Thea, Slovakia; Laboratoires Théa, Netherlands; Laboratoires Théa, Sweden; Medcor Pharmaceuticals, Netherlands; Novartis, Chile; Novartis, Ecuador; Novartis, Greece; Novartis, Indonesia; Novartis, Lebanon; Novartis, Lithuania; Novartis, New Zealand; Novartis, Paraguay; Novartis, Venezuela; Novartis AH, South Africa; Novartis Pharmaceuticals, Australia; Novartis Pharmaceuticals, Kuwait; SANDOZ, Philippines; Sigma, Portugal; Sigma-Tau, Poland; Sigma-tau Pharma Belgium, Belgium; Sun Pharma, Japan; Teva Canada, Canada; Thea, Spain; Thea, Malta; Thea, Norway; Théa, Portugal; Thea Nordic, Denmark; Thea Pharmaceuticals, United Kingdom; Novartis Singapore, Singapore
• Zaditen 0.02%
  Sun Pharma, Japan
• Zaditen 0.025%
  Laboratoires Thea, Austria
• Zaditen 0.05%
  Sun Pharma, Japan
• Zaditen 0.1%
  Sun Pharma, Japan
• Zaditen 0.25 mg/ml
  Novartis, Oman; Sigma-tau, Luxembourg; THEA, Hungary
• Zaditen 0.25%
  Novartis, Paraguay
• Zaditen 0.2mg/ml
  Novartis, Oman
• Zaditen 1mg
  Novartis, Oman
• Zaditen für Kinder [pediatric]
  Sigma-Tau Industrie Farmaceutiche Riunite, Austria
• Zaditen LP
  Alfasigma France, France
• Zaditen Ofta
  Novartis, Mexico
• Zaditen Ophtha
  Novartis Pharma, Switzerland
• Zaditen ophtha 0,25mg/ml
  Laboratoires Thea, Austria; Thea Pharma, Germany
• Zaditen Retard
  Sigma-tau Pharma Belgium, Belgium
• Zaditen SDU
  Alcon, Thailand; Laboratories Thea, Czech Republic
• Zaditen SRO
  Novartis Singapore, Singapore; SANDOZ, Philippines
• Zaditen SRO 2 mg
  Sigma-Tau Industrie Farmaceutiche Riunite, Austria
• Zaditor
  Laboratoires Thea, Canada; Laboratoires Thea, Greece
• Zalerg
  Laboratoires Théa, France; Thea, Spain
• Zalergonium
  Laboratoires Théa, France
• Zentrol
  Indufar, Paraguay
• Zikilion 0.02%
  Nichi-Iko Pharmaceutical, Japan

Glossary

Further information on drug naming conventions: International Nonproprietary Names.

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