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Fibrinolysin

ATC (Anatomical Therapeutic Chemical Classification)

B01AD05,B06AA02

CAS registry number (Chemical Abstracts Service)

0009001-90-5

Therapeutic Categories

Anticoagulant agent: Fibrinolytic enzyme

Debriding agent

Chemical Name

A proteolytic enzyme which converts fibrin into soluble products. Derived either from human plasma or from cattle (bovine fibrinolysin). The Structure consists of two polypeptide chains connected by two disulfide bonds. The heavy (A) chain (Mol wt about 65,000) originates from the amino-terminal portion of plasminogen and contains the binding sites. The light (B) chain (Mol wt about 25,000) originates from the carboxy-terminus and contains the active site

Foreign Names

  • Fibrinolysinum (Latin)
  • Fibrinolysin (German)
  • Fibrinolysine (French)
  • Fibrinolysina (Spanish)

Generic Names

  • Actase (IS)
  • Fibrinase (IS)
  • Plasmin (IS)
  • Serum tryptase (IS)
  • Thrombolysin (IS)
  • Fibrinase (IS)
  • Plasmin vom Rind (IS)
  • Plasmin, bovine (IS)
  • Plasmine bovine (IS)

Brand Names

  • Clorelase
    Pfizer, Uruguay
  • Elase [+ Deoxyribonuclease I]
    Pfizer, Kuwait; Pfizer, Malaysia
  • Fibrolan [+ Deoxyribonuclease I]
    Pfizer, Poland
  • Gino-Fibrase [+ Chloramphenicol, + Deoxyribonuclease I]
    Pfizer, Brazil
  • Saibai
    Saisheng Pharmaceutical, China
  • Fibrinase Com Cloranfenicol [+ Deoxyribonuclease I bovine, + Chloramphenicol]
    Supera RX, Brazil

Glossary

TermDefinition
ISInofficial Synonym

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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