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CAS registry number (Chemical Abstracts Service)


Chemical Formula


Molecular Weight


Therapeutic Categories

Agent for antivaricose therapy

Vasoprotective agent

Chemical Name

Saponin isolated from Aesculus hippocastanum

Foreign Names

Generic Names

  • Aescine (OS: DCF)
  • Sodium aescinate (IS)

Brand Names

  • Aescin
    Chen Ho, Taiwan; Teva, Slovakia; Teva Pharmaceuticals, Poland
  • Aescin-Teva
    Teva, Czech Republic
  • Aescuven
    Cesra, Estonia
  • Algestin (Escin and Diethylamine Salicylate)
    Nobelfarma, Georgia
  • Beta-Aescin
    New Chemical, Taiwan
  • Edeven C.M. (Escin and Diethylamine Salicylate)
    IBI, Italy
  • Ensoqone
    Ta Fong, Taiwan
  • Esceven
    Herbapol Poznan, Poland
  • Esceven (Escin and Heparin)
    Herbapol Poznan, Poland
  • Escin
    Standard, Taiwan; Yuan Chou, Taiwan
  • Escina
    Omega, Argentina
  • Escina Forte Omega (Escin and Hesperidin)
    Omega, Argentina
  • Escina Omega (Escin and Hesperidin)
    Omega, Argentina
  • Essaven (Escin and Polyenephosphatidyl Choline)
    Sanofi-Aventis, Italy
  • Esusin
    Ming Ta, Taiwan
  • Feparil (Escin and Diethylamine Salicylate)
    Rottapharm, Spain
  • Flebostasin R
    Inverni della Beffa, Italy
  • Flebostasin Retard
    Daiichi Sankyo, Spain
  • Flogencyl
    Pharma Développement, France
  • Liotontrauma (Escin and Diethylamine Salicylate)
    Sanofi-Aventis, Italy
  • Opino (Escin and Buphenine)
    Menarini, Greece
  • Prepagel (Escin and Diethylamine Salicylate)
    Recordati, Turkey
  • Recto-Reparil (Escin and Tetracaine)
    Madaus, Malta; Rottapharm, Italy
  • Recto-Reparil 4.5% + 0.5% (Escin and Tetracaine)
    Madaus, Malta
  • Repacin
    Royal, Taiwan
  • Repaderm (Escin and Diethylamine Salicylate)
    Jpi, Lebanon
  • Reparil
    Madaus, Austria; Madaus, Bulgaria; Madaus, Czech Republic; Madaus, Hong Kong; Madaus, Lebanon; Madaus, Malaysia; Madaus, Poland; Madaus, Slovakia; Madaus, Thailand; Meda, Belgium; Nycomed Pharma, Brazil; Rottapharm/Madaus, Germany; Rottapharm-Madaus, Romania
  • Reparil (Escin and Diethylamine Salicylate)
    Madaus, Hungary; Meda, Belgium; Nycomed, South Africa; Rottapharm, Italy
  • Réparil (Escin and Diethylamine Salicylate)
    Rottapharm, France
  • Reparil N (Escin and Diethylamine Salicylate)
    Grünenthal, Colombia; Madaus, Bulgaria; Madaus, Czech Republic; Madaus, Hong Kong; Madaus, Lebanon; Madaus, Poland; Madaus, Singapore; Madaus, Slovakia; Madaus, Thailand; Madaus GmbH, China; MEDA Pharma, Switzerland; Rottapharm, Taiwan; Rottapharm/Madaus, Germany; Shire, Lithuania
  • Reparilexin
    Rottapharm, Italy
  • Reparil-Gel N (Escin and Diethylamine Salicylate)
    Madaus, Hong Kong
  • Reparil-N (Escin and Diethylamine Salicylate)
    Abdi Ibrahim, Turkey; Madaus, Georgia; Madaus, Malaysia; Madaus, Philippines
  • Rubogel Genfar (Escin and Diethylamine Salicylate)
    Genfar, Colombia; Genfar, Ecuador; Genfar, Peru; Genfar S.A., Dominican Republic; Genfar S.A., El Salvador
  • Somatoline (Escin and Levothyroxine)
    Manetti Roberts, Italy
  • Troxeven Forte (Escin and Troxerutin)
    Craveri, Argentina
  • Tubarine (Escin and Troxerutin)
    Spedrog-Caillon, Argentina
  • Varixina
    Sherfarma, Peru
  • Veinofytol
    Tilman, Belgium
  • Velosil
    Winston, Taiwan
  • Venastat
    Boehringer Ingelheim, Hungary
  • Venitan
    Lek d.d., Russian Federation; Sandoz, Slovakia
  • Venitan forte (Escin and Heparin)
    Lek, Bosnia & Herzegowina; Lek, Slovenia; Lek d.d., Russian Federation
  • Venitan N
    Lek d.d., Russian Federation
  • Venoparil (Escin and Diethylamine Salicylate)
    Neo-Farmacêutica, Portugal
  • Venoplant
    VSM, Belgium
  • Venosin retard
    Klinge Pharma, Austria
  • Venostasin
    Klinge Pharma, Austria
  • Venotop
    Dr. Willmar Schwabe, Portugal
  • Yellon (Escin and Heparin)
    Slovakofarma, Lithuania
  • Aescin Sodium - Changlian Laifu
    Changlian Laifu Biochemical Pharmaceutical, China
  • Edevexin
    IBI, Italy
  • Mai Tong Na
    Luye Pharma, China
  • Ou Kai
    Luye Pharma, China
  • Ou Lai (Escin and Diethylamine Salicylate)
    Luye Pharma, China
  • Reparil
    Nycomed Pharma, Brazil
  • Reparil (Escin and Diethylamine Salicylate)
    Nycomed Pharma, Brazil
  • Reparil-N (Escin and Diethylamine Salicylate)
    Madaus, Oman


DCFDénomination Commune Française
ISInofficial Synonym
OSOfficial Synonym

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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