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Coagulation Factor VIII, Human

Scheme

Ph. Eur.

ATC (Anatomical Therapeutic Chemical Classification)

B02BD02

CAS registry number (Chemical Abstracts Service)

0009001-27-8

Therapeutic Categories

Hemostatic agent

Blood coagulation factor substitute

Chemical Name

Human coagulation factor VIII is a preparation of plasma protein fraction that contains the glycoprotein coagulation factor VIII (plasma and serum glycoprotein involved in blood coagulation) together with varying amounts of Willebrand factor, depending on the method of preparation

Foreign Names

  • Factor VIII coagulationis sanguinis humanus (Latin)
  • Blutgerinnungsfaktor VIII vom Menschen (German)
  • Facteur VIII de coagulation sanguine humain (French)
  • Factor VIII de coagulacion sanguinea humana (Spanish)

Generic Names

  • AHF A (IS)
  • AHG (IS)
  • Antihemophilic factor A (IS)
  • Antihemophilic globulin (IS)
  • Antihemophilic globulin A (IS)
  • Factor VIII, human (IS)
  • Dried Factor VIII Fraction (PH: BP 2018)
  • Factor VIII coagulationis humanus (PH: Ph. Eur. 9)
  • Human coagulation factor VIII (PH: Ph. Eur. 9)

Brand Names

  • 8Y
    Bio Products Laboratory, Vietnam; Ikapharmindo, Indonesia
  • Aafact
    Graha, Indonesia; Sanquin, Netherlands
  • Actif-VIII
    Aventis Pasteur, Pakistan
  • Advate
    Baxter, Estonia; Baxter, Tunisia; Green Cross, South Korea
  • Afstyla
    CSL Behring, Estonia
  • Agemfil A
    National Medical Research Center of Hematology, Russian Federation
  • Aleviate
    CSL Behring, Hong Kong
  • Alphanate
    Alpha Ther. Italia, Italy; Grifols, Bangladesh; Grifols, Hong Kong; Grifols, Philippines; Grifols, Thailand; Grifols, Taiwan
  • Alphanate [+ Von Willebrand Factor, Human]
    Grifols, Netherlands; Grifols, United States; Grifols Chile, Chile; Grifols UK, United Kingdom
  • Amofil
    Sanquin, Finland
  • Beriate
    Biotoscana, Colombia; CSL Behring, Spain; CSL Behring, Italy; CSL Behring, Macedonia; Farma-Tek, Turkey; PharmaSwiss, Croatia (Hrvatska); PharmaSwiss, Serbia; ZLB Behring, Georgia
  • Beriate 100 I.E/ml
    CSL Behring, Austria; CSL Behring, Hungary
  • Beriate 1000
    CSL Behring, Germany; CSL Behring, Poland; CSL Behring, Romania
  • Beriate 1000 IE
    CSL Behring, Bulgaria; CSL Behring, Switzerland
  • Beriate 200 I.E/ml
    CSL Behring, Austria; CSL Behring, Hungary
  • Beriate 2000
    CSL Behring, Germany; CSL Behring, Poland; CSL Behring, Romania
  • Beriate 2000 IE
    CSL Behring, Bulgaria
  • Beriate 250
    CSL Behring, Germany; CSL Behring, Poland; CSL Behring, Romania
  • Beriate 250 IE
    CSL Behring, Bulgaria; CSL Behring, Switzerland
  • Beriate 500
    CSL Behring, Germany; CSL Behring, Poland; CSL Behring, Romania
  • Beriate 500 IE
    CSL Behring, Bulgaria; CSL Behring, Switzerland
  • Beriate P
    CSL Behring, Taiwan
  • Beriplast P [+ Aprotinin, + Calcium Chloride, + Fibrinogen, Human, + Thrombin]
    CSL Behring, Hong Kong
  • Beriplex P/N [+ Coagulation Factor II, Human, + Coagulation Factor IX, Human, + Coagulation Factor X, Human]
    CSL Behring, Argentina
  • Biostate
    CSL Behring, Hong Kong
  • Biostate [+ Von Willebrand Factor, Human]
    CSL Behring, Australia
  • Conco-Eight-HT
    Japan Blood Products Organization, Japan
  • Confact F
    Chemo-Sero-Therapeutic Research Institut Kaketsuken, Japan
  • Cross Eight MC
    Japan Blood Products Organization, Japan
  • Dried Factor VIII Fraction
    Bio Products Laboratory, Malta; BPL, Oman
  • Dried Factor VIII Fraction, type 8Y [+ Von Willebrand Factor, Human]
    Bio Products Laboratory, United Kingdom; Bio Products Laboratory, Macedonia
  • Eco Factor VIII
    PAL, Paraguay
  • Emoclot
    Biofactor, Argentina; Jasika, Croatia (Hrvatska); Kedrion, Bosnia & Herzegowina; Kedrion, Bulgaria; Kedrion, Georgia; Kedrion, Italy; Kedrion, Macedonia; Kedrion, Malta; Kedrion, Romania; Kedrion, Serbia; Kedrion, Tunisia; KEDRION S.p.A., Poland; Kedrion SpA, Thailand; Onko-Koçsel, Turkey
  • Factane
    CAF-DCF, Belgium
  • Factor VIII Antihemofilico Unc
    Hemoderivados, Argentina
  • Factor VIII Farmatec
    Farmatec, Uruguay
  • Factor VIII Humano 25 UI/ml
    Quimbiotec, Venezuela
  • Factor VIII SDH 1000 [+ Glycine]
    Biotest, Kuwait
  • Factor VIII SDH 250 [+ Glycine]
    Biotest, Kuwait
  • Factor VIII SDH 500 [+ Glycine]
    Biotest, Kuwait
  • Faktor VIII
    Vitalis, Turkey
  • Faktor VIII SDH Intersero
    Intersero, Germany
  • Fanhdi
    Biognost, Croatia (Hrvatska); Dem Ilac, Turkey; Demo, Greece; Grifols, Spain; Grifols, Portugal; Grifols, Romania; Grifols, Slovakia; Grifols Arg., Argentina; Grifols Chile, Chile; Grifols Italia, Italy; Grifols UK, United Kingdom; Instituto Grifols, Serbia
  • Fanhdi [+ Histidine]
    Grifols, Paraguay
  • Fanhdi [+ Von Willebrand Factor, Human]
    Grifols, Czech Republic
  • Fanhdi 1000 I.E. [+ Von Willebrand Factor, Human]
    Grifols, Germany
  • Fanhdi 1000UI
    Grifols, Bulgaria; Grifols, Paraguay
  • Fanhdi 100iu/ml
    Instituto Grifols, Israel
  • Fanhdi 1500 I.E. [+ Von Willebrand Factor, Human]
    Grifols, Germany
  • Fanhdi 250 I.E. [+ Von Willebrand Factor, Human]
    Grifols, Germany
  • Fanhdi 250 UI
    Grifols, Bulgaria
  • Fanhdi 25iu/ml
    Instituto Grifols, Israel
  • Fanhdi 500 I.E. [+ Von Willebrand Factor, Human]
    Grifols, Germany
  • Fanhdi 500 UI
    Grifols, Bulgaria
  • Fanhdi 50iu/ml
    Instituto Grifols, Israel
  • Feiba
    Baxter Oncology, Macedonia; Eczacibasi Baxter, Turkey
  • Fibrogammin P
    CSL Behring, Brazil
  • Gamunex 10%
    Talecris, Oman
  • Green VIII
    Laboratorios Biosano, Chile
  • Green VIII Factor
    Green Cross, Egypt
  • Greengene
    Laboratorios Biosano, Chile
  • Greenmono
    Green Cross, South Korea
  • Haemate [+ Von Willebrand Factor, Human]
    CSL Behring, Denmark; CSL Behring, Finland; CSL Behring, Norway; CSL Behring, Sweden
  • Haemate 1200 NE/500 NE [+ Von Willebrand Factor, Human]
    CSL Behring, Hungary
  • Haemate P
    Biotoscana, Colombia; CSL Behring, Italy; CSL Behring, Taiwan
  • Haemate P [+ Von Willebrand Factor, Human]
    CSL Behring, Argentina; CSL Behring, Austria; CSL Behring, Belgium; CSL Behring, Brazil; CSL Behring, Cyprus; CSL Behring, Czech Republic; CSL Behring, Spain; CSL Behring, Greece; CSL Behring, Netherlands; CSL Behring, Poland; CSL Behring, Portugal; CSL Behring, Romania; CSL Behring, Slovenia; CSL Behring UK, United Kingdom; PharmaSwiss, Croatia (Hrvatska); ZLB Behring, Georgia
  • Haemate P 1000 [+ Von Willebrand Factor, Human]
    Biotest, Switzerland; CSL Behring, Germany; CSL Behring, Israel; CSL Behring, Serbia; CSL Behring, Tunisia
  • Haemate P 1200/500 [+ Von Willebrand Factor, Human]
    CSL, Luxembourg
  • Haemate P 2400/1000 [+ Von Willebrand Factor, Human]
    CSL, Luxembourg
  • Haemate P 250 [+ Von Willebrand Factor, Human]
    CSL Behring, Switzerland; CSL Behring, Germany; CSL Behring, Israel; CSL Behring, Serbia; CSL Behring, Tunisia
  • Haemate P 500 [+ Von Willebrand Factor, Human]
    Biotest, Switzerland; CSL Behring, Germany; CSL Behring, Israel; CSL Behring, Serbia; CSL Behring, Tunisia
  • Haemate P 600/250 [+ Von Willebrand Factor, Human]
    CSL, Luxembourg
  • Haemate-P
    CSL Behring, Turkey
  • Haemoctin
    Biotest, Egypt; Biotest, Spain; Biotest, Poland; Biotest Italia, Italy; Kimia Farma, Indonesia; Vianex, Greece; Biotest UK, United Kingdom
  • Haemoctin 1000 IE
    Biotest, Bulgaria; Biotest, Switzerland
  • Haemoctin 1000 NE
    Biotest, Hungary
  • Haemoctin 250 IE
    Biotest, Bulgaria; Biotest, Switzerland
  • Haemoctin 500 IE
    Biotest, Bulgaria; Biotest, Switzerland
  • Haemoctin SDH
    Biotest, Bosnia & Herzegowina; Biotest, Czech Republic; Biotest, Hong Kong; Biotest, Malta; Biotest, Romania; Biotest, Thailand; Biotest, Taiwan; Biotest Pharma GmbH, Serbia
  • Haemoctin SDH 100 I.E./ml
    Biotest Austria, Austria
  • Haemoctin SDH 1000
    Biotest, Germany; Biotest, Israel
  • Haemoctin SDH 250
    Biotest, Germany; Biotest, Israel; Biotest, Oman; Biotest, Tunisia; Biotest Pharma GmH, Vietnam
  • Haemoctin SDH 50 I.E./ml
    Biotest Austria, Austria
  • Haemoctin SDH 500
    Biotest, Germany; Biotest, Israel; Biotest, Oman; Biotest, Tunisia; Biotest Pharma GmH, Vietnam
  • Haemoctin-SDH
    Kansuk, Turkey
  • Helixate Nexgen
    Bayer, Estonia
  • Hemofil
    Baxter, Brazil
  • Hemofil M
    Eczacibasi Baxter, Turkey; FU, Uruguay; Tuteur, Argentina; Baxter, Lithuania; Baxter, Thailand; Baxter, Taiwan
  • Hemoraas
    Delta, Colombia; Shanghai Raas, Georgia
  • High Purity Factor VIII CSL Limited
    CSL Behring, Taiwan
  • High Purity Factor VIII Scottish
    Scottish, Taiwan
  • Humaclot 1000 NE
    Human BioPlazma, Hungary
  • Humaclot 500 NE
    Human BioPlazma, Hungary
  • Humate-P [+ Von Willebrand Factor, Human]
    CSL Behring, Canada; CSL Behring, United States
  • Iblias
    Bayer, Lithuania
  • Immunate
    Agmar, Croatia (Hrvatska); Baxalta, Slovakia; Baxter, Lithuania; Baxter Arg., Argentina; Baxter-RM, Italy; Eczacibasi Baxter, Turkey; Shire Sweden, Sweden
  • Immunate [+ Von Willebrand Factor, Human]
    Baxalta, Finland; Baxalta Deutschland, Germany; Baxalta Innovations, Estonia; Baxalta Innovations, Lithuania; Baxalta Innovations, Netherlands; Baxalta Innovations, Romania; Baxter, Bosnia & Herzegowina; Baxter, Georgia; Baxter, Malta; Baxter, Thailand; Baxter, Tunisia; Baxter AG, Serbia; FU, Uruguay
  • Immunate 1000 I.E. FVIII/750 I.E. VWF [+ Von Willebrand Factor, human]
    Baxter, Bulgaria; Baxter Healthcare, Austria
  • Immunate 1000IU
    Baxter, Israel
  • Immunate 250 I.E. FVIII/190 I.E. VWF [+ Von Willebrand Factor, Human]
    Baxter, Bulgaria
  • Immunate 250IU
    Baxter, Israel
  • Immunate 500 I.E. FVIII/375 I.E. VWF [+ Von Willebrand Factor, human]
    Baxter, Bulgaria; Baxter Healthcare, Austria
  • Immunate 500IU
    Baxter, Israel
  • Immunate Baxter
    Baxter, Cyprus
  • Immunate Baxter [+ Von Willebrand Factor, Human]
    Baxter, Poland
  • Immunate S/D
    Baxter, Brazil; Baxter, Macedonia
  • Immunate S/D 1000 NE FVIII/750 NE VWF [+ Von Willebrand Factor, Human]
    Baxter, Hungary
  • Immunate S/D 1000IE
    Shire, Switzerland
  • Immunate S/D 250IE
    Shire, Switzerland
  • Immunate S/D 500 NE FVIII/375 NE VWF [+ Von Willebrand Factor, Human]
    Baxalta Innovations, Hungary
  • Immunate S/D 500IE
    Shire, Switzerland
  • Immunate Stim Plus [+ Von Willebrand Factor, Human]
    Shire, Czech Republic
  • Innovate
    Biomed Lublin, Poland
  • Intratect 50mg/ml
    Biotest, Oman
  • Kiovig 100mg/ml
    Baxter, Oman
  • Koate Dvi
    Talecris, Egypt
  • Koate HP
    Bayer, Pakistan; Popular, Pakistan
  • Koate-DVI
    Bayer, Lithuania; Bayer Pharmaceuticals, Kuwait; Biem, Turkey; Gador, Uruguay; Grifols, Hong Kong; Grifols, Macedonia; Instituto Grifols, Serbia; Talecris, Taiwan; Tuteur, Argentina
  • Koate-DVI 1000
    Grifols Therapeutic, Israel
  • Koate-DVI 250
    Grifols Therapeutic, Israel
  • Koate-DVI 500
    Grifols Therapeutic, Israel
  • Kogenate
    Bayer, Oman; Bayer de México, Mexico
  • Kogenate Bayer
    Bayer HealthCare, Macedonia
  • Kogenate FS
    Bayer, China; Bayer, Tunisia; Bayer, Uruguay; BHC-Bayer, Colombia; Bayer BSP, Argentina
  • Kovaltry
    Bayer, Lithuania
  • Monarc M
    Teva-Tuteur, Paraguay
  • Monoclate-P
    Zydus Cadila, India
  • NovoEight
    Novo Nordisk, Argentina
  • NovoEight 1000 NE
    Novo Nordisk, Hungary
  • NovoEight 1500 NE
    Novo Nordisk, Hungary
  • NovoEight 2000 NE
    Novo Nordisk, Hungary
  • NovoEight 3000 NE
    Novo Nordisk, Hungary
  • NovoEight 500 NE
    Novo Nordisk, Hungary
  • NovoSeven RT
    Novo Nordisk, Colombia
  • NovoThirteen
    Novo Nordisk, Israel
  • NovoThirteen 2500 NE
    Novo Nordisk, Hungary
  • Nuwiq
    Varifarma, Argentina
  • Octafil [+ Von Willebrand Factor, Human]
    Octapharma, Finland
  • Octanate
    Berk, Turkey; Jana, Croatia (Hrvatska); Laboratorio Bago, Chile; Landson, Indonesia; Octapharma, Bosnia & Herzegowina; Octapharma, Belgium; Octapharma, Bulgaria; Octapharma, Bulgaria; Octapharma, Czech Republic; Octapharma, Denmark; Octapharma, Estonia; Octapharma, Spain; Octapharma, France; Octapharma, United Kingdom; Octapharma, Georgia; Octapharma, Italy; Octapharma, Lithuania; Octapharma, Latvia; Octapharma, Macedonia; Octapharma, Malta; Octapharma, Mexico; Octapharma, Netherlands; Octapharma, Norway; Octapharma, Oman; Octapharma, Poland; Octapharma, Romania; Octapharma, Sweden; Octapharma, Tunisia; Octapharma, Tunisia; Octapharma - Produtos Farmacêuticos Lda., Portugal; Octapharma Pharmazeutika, Bulgaria; Varifarma, Argentina
  • Octanate [+ Von Willebrand Factor, Human]
    Clausen, Uruguay
  • Octanate 1000
    Octapharma, Germany; Octapharma, Israel; Octapharma, Serbia
  • Octanate 1000 IE
    Octapharma, Switzerland
  • Octanate 1000 NE
    Octapharma, Hungary
  • Octanate 100IU/ml
    Octapharma Pharmazeutika, Austria
  • Octanate 100UI/ml
    Octapharma, Luxembourg
  • Octanate 200IU/ml
    Octapharma Pharmazeutika, Austria
  • Octanate 200UI/ml
    Octapharma, Luxembourg
  • Octanate 250
    Octapharma, Germany; Octapharma, Serbia
  • Octanate 250 IE
    Octapharma, Switzerland
  • Octanate 250 NE
    Octapharma, Hungary
  • Octanate 500
    Octapharma, Germany; Octapharma, Israel; Octapharma, Serbia
  • Octanate 500 IE
    Octapharma, Switzerland
  • Octanate 500 NE
    Octapharma, Hungary
  • Octanate 500UI/ml
    Octapharma, Luxembourg
  • Octanate 50IU/ml
    Octapharma Pharmazeutika, Austria
  • Octanate 50UI/ml
    Octapharma, Luxembourg
  • Octanate LV
    Octapharma, Bosnia & Herzegowina; Octapharma, Denmark; Octapharma, United Kingdom
  • Octonativ-M
    Pharmacia & Upjohn, Kuwait
  • Optivate
    Bio Products Laboratory, Cyprus; Bio Products Laboratory, Lithuania; Bio Products Laboratory, Poland; GP Pharm, Argentina; Landsteiner, Mexico
  • Optivate [+ Von Willebrand Factor, Human]
    Bio Products, Germany; Bio Products Laboratory, United Kingdom; Bio Products Laboratory, Georgia; Bio Products Laboratory, Malta; Bio Products Laboratory, Romania
  • Optivate 100 I.U./ml
    Bio Products, Oman
  • Optivate 1000 IU [+ Von Willebrand Factor, Human]
    Bio Products Laboratory, Israel
  • Optivate 500 IU [+ Von Willebrand Factor, Human]
    Bio Products Laboratory, Israel
  • Pentaglobin 50 mg/ml
    Biotest, Oman
  • Prothromplex [+ Coagulation Factor IX, Human, + Coagulation Factor II, + Coagulation Factor X, Human, + Protein C, Human]
    Baxalta Innovations, Netherlands
  • ReFacto AF 1000 IU
    Pfizer, Turkey
  • ReFacto AF 2000 IU
    Pfizer, Turkey
  • ReFacto AF 250 IU
    Pfizer, Turkey
  • ReFacto AF 500 IU
    Pfizer, Turkey
  • Talate [+ Von Willebrand Factor, Human]
    Baxter-RM, Italy
  • Tisseel [+ Aprotinin, + Calcium Chloride, + Fibrinogen, Human, + Thrombin]
    Baxter, Hungary; Dalim, South Korea
  • Vihuma
    Octapharma, Lithuania
  • Voncento [+ Von Willebrand Factor, Human]
    CSL Behring, Germany; CSL Behring, Estonia; CSL Behring, France; CSL Behring, Lithuania; CSL Behring, Netherlands; CSL Behring, Poland; CSL Behring, Sweden; CSL Behring GmbH, Greece; CSL Behring UK, United Kingdom
  • Voncento 1000 I.E./2400 I.E. [+ Von Willebrand Factor, Human]
    CSL Behring, Switzerland
  • Voncento 500 I.E./1200 I.E. [+ Von Willebrand Factor, Human]
    CSL Behring, Switzerland
  • Wilate [+ Von Willebrand Factor, Human]
    Clausen, Uruguay; Jana, Croatia (Hrvatska); Laboratorio Bago, Chile; Octapharma, Bosnia & Herzegowina; Octapharma, Belgium; Octapharma, Brazil; Octapharma, Canada; Octapharma, Czech Republic; Octapharma, Estonia; Octapharma, Spain; Octapharma, Finland; Octapharma, United Kingdom; Octapharma, Lithuania; Octapharma, Macedonia; Octapharma, Netherlands; Octapharma, Norway; Octapharma, Romania; Octapharma, Sweden; Octapharma, Slovenia; Octapharma, Tunisia; Octapharma Pharmazeutika, Bulgaria; Varifarma, Argentina
  • Wilate 1000 [+ Von Willebrand Factor, Human]
    Octapharma, Germany; Octapharma, Israel; Octapharma, Luxembourg; Octapharma, Serbia; Octapharma - Produtos Farmacêuticos Lda., Portugal
  • Wilate 1000 I.E. VWF und 1000 I.E. FVII [+ Von Willebrand Factor, Human]
    Octapharma Pharmazeutika, Austria
  • Wilate 1000 IE [+ Von Willebrand Factor, Human]
    Octapharma, Switzerland
  • Wilate 1000 NE VWF/1000 NE FVIII [+ Von Willebrand Factor, Human]
    Octapharma, Hungary
  • Wilate 450 [+ Von Willebrand Factor, human]
    Octapharma, Serbia
  • Wilate 450 I.E. FVIII und 400 I.E. VWF [+ Von Willebrand Factor, Human]
    Octapharma Pharmazeutika, Austria
  • Wilate 500 [+ Von Willebrand Factor, Human]
    Octapharma, Germany; Octapharma, Luxembourg; Octapharma, Serbia; Octapharma - Produtos Farmacêuticos Lda., Portugal
  • Wilate 500 I.E. VWF und 500 I.E. FVII [+ Von Willebrand Factor, Human]
    Octapharma Pharmazeutika, Austria
  • Wilate 500 IE [+ Von Willebrand Factor, Human]
    Octapharma, Switzerland
  • Wilate 900 [+ Von Willebrand Factor, human]
    Octapharma, Serbia
  • Wilate 900 I.E. FVIII und 800 I.E. VWF [+ Von Willebrand Factor, Human]
    Octapharma Pharmazeutika, Austria
  • Wilnativ [+ Von Willebrand Factor, Human]
    Octapharma, Denmark
  • Wilstart [+ Von Willebrand Factor, Human]
    LFB, France
  • Xyntha
    Pfizer, Argentina; Pfizer, Peru
  • Zmogaus VIII koaguliacijos faktorius NKC
    Nacionalinis kraujo centras, Lithuania

Glossary

TermDefinition
ISInofficial Synonym
PHPharmacopoeia Name
Ph. Eur.European Pharmacopoeia

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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