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Afoxolaner

In some countries, this medicine may only be approved for veterinary use.

Scheme

Rec.INN

CAS registry number (Chemical Abstracts Service)

1093861-60-9

Chemical Formula

C26-H17-Cl-F9-N3-O3

Molecular Weight

626

Therapeutic Category

Ectoparasiticide for topical use and insecticide

Chemical Name

4-{5-[3-chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4,5-dihydro-1,2-oxazol-3-yl}-N-{2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}naphthalene-1-carboxamide (WHO)

Foreign Names

  • Afoxolanerum (Latin)
  • Afoxolaner (German)
  • Afoxolaner (French)
  • Afoxolaner (Spanish)

Generic Names

  • Afoxolaner (OS: USAN)
  • UNII-02L07H6D0U (IS)

Brand Names

  • NexGard [veterinary use]
    Boehrvet BI-Vetmedica, Germany; Faunapharma, Finland; Merial, Estonia; Merial, United Kingdom; Merial, Iceland; Merial, Norway; Merial, Poland; Merial, United States
  • NEXGARD [veterinary use]
    Merial Norden, Sweden
  • NexGard 11 für Hunde [veterinary use]
    Biokema, Switzerland
  • NexGard 11 mg für Hunde 2-4 kg [veterinary use]
    Merial, Austria
  • Nexgard 11.3 mg voor honden [veterinary use]
    Merial, Netherlands
  • NexGard 11.3mg for Dogs 2-4kg [veterinary use]
    Merial Australia, Australia
  • NexGard 11mg pour chiens de 2-4kg [veterinary use]
    Merial, France
  • NexGard 136 für Hunde [veterinary use]
    Biokema, Switzerland
  • NexGard 136 mg für Hunde > 25-50 kg [veterinary use]
    Merial, Austria
  • Nexgard 136 mg voor honden [veterinary use]
    Merial, Netherlands
  • NexGard 136mg for Dogs 25.1-50kg [veterinary use]
    Merial Australia, Australia
  • NexGard 136mg pour chiens > 25-50kg [veterinary use]
    Merial, France
  • NexGard 28 für Hunde [veterinary use]
    Biokema, Switzerland
  • NexGard 28 mg für Hunde >4-10 kg [veterinary use]
    Merial, Austria
  • Nexgard 28.3 mg voor honden [veterinary use]
    Merial, Netherlands
  • NexGard 28.3mg for Dogs 4.1-10kg [veterinary use]
    Merial Australia, Australia
  • NexGard 28mg pour chiens > 4-10kg [veterinary use]
    Merial, France
  • NexGard 68 für Hunde [veterinary use]
    Biokema, Switzerland
  • NexGard 68 mg für Hunde >10-25 kg [veterinary use]
    Merial, Austria
  • Nexgard 68 mg voor honden [veterinary use]
    Merial, Netherlands
  • NexGard 68mg for Dogs 10.1-25kg [veterinary use]
    Merial Australia, Australia
  • NexGard 68mg pour chiens > 10-25kg [veterinary use]
    Merial, France
  • NexGard Chiens [veterinary use]
    Merial, Belgium
  • NEXGARD SPECTRA [+ Milbemycin] [veterinary use]
    Merial Norden, Sweden
  • Nexgard Spectra [+ Milbemycin] [veterinary use]
    Boehrvet BI-Vetmedica, Germany; Faunapharma, Finland; Merial, Estonia; Merial, United Kingdom; Merial, Iceland; Merial, Poland
  • NexGard Spectra 11 für Hunde von 2 - 3.5kg [+ Milbemycin Oxime] [veterinary use]
    Biokema, Switzerland
  • NexGard Spectra 150 mg/30 mg pour chiens > 30 - 60kg [+ Milbemycin Oxime] [veterinary use]
    Merial, France
  • Nexgard Spectra 150 mg/30 mg voor honden [+ Milbemycin] [veterinary use]
    Merial, Netherlands
  • Nexgard Spectra 150mg/30mg für Hunde [+ Milbemycin] For dogs [veterinary use]
    Merial, Austria
  • NexGard Spectra 180 für Hunde von >30 - 60kg [+ Milbemycin Oxime] [veterinary use]
    Biokema, Switzerland
  • NexGard Spectra 19 mg/4 mg pour chiens > 3.5 - 7.5kg [+ Milbemycin Oxime] [veterinary use]
    Merial, France
  • Nexgard Spectra 19 mg/4 mg voor honden [+ Milbemycin] [veterinary use]
    Merial, Netherlands
  • NexGard Spectra 19mg/4mg für Hunde [+ Milbemycin Oxime] [veterinary use]
    Merial, Austria
  • NexGard Spectra 22 für Hunde von >3.5kg - 7.5kg [+ Milbemycin Oxime] [veterinary use]
    Biokema, Switzerland
  • NexGard Spectra 38 mg/8 mg pour chiens > 7.5 - 15kg [+ Milbemycin Oxime] [veterinary use]
    Merial, France
  • Nexgard Spectra 38 mg/8 mg voor honden [+ Milbemycin] [veterinary use]
    Merial, Netherlands
  • Nexgard Spectra 38mg/8mg für Hunde [+ Milbemycin] For dogs [veterinary use]
    Merial, Austria
  • NexGard Spectra 45 für Hunde von >7.5kg - 15kg [+ Milbemycin Oxime] [veterinary use]
    Biokema, Switzerland
  • NexGard Spectra 75 mg/15 mg pour chiens > 15 - 30kg [+ Milbemycin Oxime] [veterinary use]
    Merial, France
  • Nexgard Spectra 75 mg/15 mg voor honden [+ Milbemycin] [veterinary use]
    Merial, Netherlands
  • NexGard Spectra 75mg/15mg für Hunde [+ Milbemycin] For dogs [veterinary use]
    Merial, Austria
  • NexGard Spectra 9 mg/2 mg pour chiens 2-3.5kg [+ Milbemycin Oxime] [veterinary use]
    Merial, France
  • Nexgard Spectra 9 mg/2 mg voor honden [+ Milbemycin] [veterinary use]
    Merial, Netherlands
  • NexGard Spectra 90 für Hunde von >15kg - 30kg [+ Milbemycin Oxime] [veterinary use]
    Biokema, Switzerland
  • NexGard Spectra 9mg/2mg für Hunde [+ Milbemycin] For dogs [veterinary use]
    Merial, Austria
  • NexGard Spectra for Dogs [+ Milbemycin Oxime] [veterinary use]
    Merial Australia, Australia

Glossary

TermDefinition
ISInofficial Synonym
OSOfficial Synonym
Rec.INNRecommended International Nonproprietary Name (World Health Organization)
USANUnited States Adopted Name
WHOWorld Health Organization

Further information on drug naming conventions: International Nonproprietary Names.

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Further information

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