Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- doxepin
- Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Interactions between your drugs
doxepin ethinyl estradiol
Applies to: doxepin, Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
Drug and food interactions
norethindrone food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Grapefruit juice may increase the blood levels of certain medications such as norethindrone. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norethindrone. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
doxepin food
Applies to: doxepin
Ask your doctor before using doxepin together with ethanol, this can alter the effects of doxepin and cause increased side effects. Call the doctor if you experience uneven heartbeats, extreme drowsiness, confusion, agitation, vomiting, blurred vision, sweating, muscle stiffness, feeling light-headed, and seizures. You should be warned not to exceed recommended dosages, to avoid alcohol, and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
ethinyl estradiol food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
norethindrone food
Applies to: Loestrin 24 Fe (ethinyl estradiol / norethindrone)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Learn more
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.